Valganciclovir

Product Name: Valganciclovir
CAS No.: 175865-60-8
Chemical Name: Valganciclovir
Synonyms: Valgancyclovir;Valganciclov;valganciclovir;Valganciclovir-d8;Valganciclovir-d8 (Mixture of Diastereomers);Valganciclovir & Valganciclovir Hydrochloride;Valganciclovir-d5 HCl (Mixture of diastetroMers);L-Valine, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl ester;(2S)-2-((2-AMino-6-oxo-1H-purin-9(6H)-yl)Methoxy)-3-hydroxypropyl 2-aMino-3-Methylbutanoate;2-amino-3-methylbutanoic acid [2-[(2-amino-6-oxo-3H-purin-9-yl)methoxy]-3-hydroxypropyl] ester
CBNumber: CB0855239
Molecular Formula: C14H22N6O5
Formula Weight: 354.36
MOL File: 175865-60-8.mol

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Valganciclovir Property

Density: 1.59±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
pka: 9.32±0.20(Predicted)
BCS Class: 3
InChI: InChI=1S/C14H22N6O5/c1-7(2)9(15)13(23)24-4-8(3-21)25-6-20-5-17-10-11(20)18-14(16)19-12(10)22/h5,7-9,21H,3-4,6,15H2,1-2H3,(H3,16,18,19,22)/t8?,9-/m0/s1
InChIKey: WPVFJKSGQUFQAP-GKAPJAKFSA-N
SMILES: C(OCC(OCN1C2=C(N=C1)C(=O)NC(N)=N2)CO)(=O)[C@H](C(C)C)N
CAS DataBase Reference: 175865-60-8(CAS DataBase Reference)

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Safety

Hazardous Substances Data: 175865-60-8(Hazardous Substances Data)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Matrix Scientific

Product number: 097028
Product name: (2S)-2-((2-Amino-6-oxo-1H-purin-9(6H)-yl)methoxy)-3-hydroxypropyl 2-amino-3-methylbutanoate
Purity: 95+%
Packaging: 250mg
Price: $364
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 33627
Product name: Valganciclovir
Purity: 98%purewithdatedHPLCUVchromatogram
Packaging: 1mg
Price: $685
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0004848
Product name: VALGANCICLOVIR
Purity: 95.00%
Packaging: 0.25G
Price: $764
Updated: 2021/12/16

Matrix Scientific

Product number: 097028
Product name: (2S)-2-((2-Amino-6-oxo-1H-purin-9(6H)-yl)methoxy)-3-hydroxypropyl 2-amino-3-methylbutanoate
Purity: 95+%
Packaging: 1g
Price: $807
Updated: 2021/12/16

AK Scientific

Product number: Y0321
Product name: Valganciclovir
Packaging: 1g
Price: $1139
Updated: 2021/12/16

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Valganciclovir Chemical Properties,Usage,Production

Uses

Antiviral.

Uses

Valganciclovir-d8, is the labeled analogue of Valganciclovir (V092000), a pro-drug of Ganciclovir, used in treatment of retro-virus.

Definition

ChEBI: The L-valinyl ester of ganciclovir, into which it is rapidly converted by intestinal and hepatic esterases. It is a synthetic analogue of 2'-deoxyguanosine.

Indications

Valganciclovir (Valcyte) is the L-valyl ester prodrug of ganciclovir.

brand name

Valcyte (Roche).

Clinical Use

Oral valganciclovir is comparable to intravenous ganciclovir for the treatment and suppression of CMV retinitis in AIDS patients.

Drug interactions

Potentially hazardous interactions with other drugs
Antibacterials: increased risk of convulsions with imipenem-cilastatin.
Antivirals: possibly increased didanosine concentration; profound myelosuppression with zidovudine - avoid if possible.
Mycophenolate: possibly increased concentrations of both mycophenolic acid and ganciclovir.
Increased risk of myelosuppression with other myelosuppressive drugs.

Metabolism

Valganciclovir is well absorbed from the gastrointestinal tract and rapidly and extensively metabolised in the intestinal wall and liver to ganciclovir. Valganciclovir is eliminated in the urine as unchanged ganciclovir, mainly by glomerular filtration and also active tubular secretion.

Valganciclovir Preparation Products And Raw materials

Raw materials

Preparation Products

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Valganciclovir Suppliers

China 90 Europe 2 Germany 1 India 17 Italy 1 United Kingdom 1 United States 15 Global 127

Parth Antibiotics Pvt Ltd.

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Triveni Interchem Pvt.Ltd.

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Rakshit Drugs Private Limited

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Pharmaffiliates Analytics and Synthetics P. Ltd

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ProdList: 6739
Advantage: 58

A.J Chemicals

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Country: India
ProdList: 6100
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Medilink Pharmachem

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Email: exports@medilinkpharma.com
Country: India
ProdList: 424
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View Lastest Price from Valganciclovir manufacturers

HangZhou RunYan Pharma Technology Co.,LTD.

Product: Valganciclovir 175865-60-8
Price: US $0.00-0.00/g
Min. Order: 10g
Purity: 99% HPLC
Supply Ability: 10000
Release date: 2024-09-11

Sinoway Industrial co., ltd.

Product: Valganciclovir 175865-60-8
Price: US $0.00/Kg/Bag
Min. Order: 2Kg/Bag
Purity: 99% up, High Density
Supply Ability: 20 tons
Release date: 2021-07-14

Henan Aochuang Chemical Co.,Ltd.

Product: Valganciclovir 175865-60-8
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-29

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Valganciclovir-d8

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Valgancyclovir

Valganciclovir-d5 HCl (Mixture of diastetroMers)

Valganciclovir-d8 (Mixture of Diastereomers)

2-amino-3-methylbutanoic acid [2-[(2-amino-6-oxo-3H-purin-9-yl)methoxy]-3-hydroxypropyl] ester

Valganciclov

L-Valine, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl ester

ValganciclovirQ: What is Valganciclovir Q: What is the CAS Number of Valganciclovir Q: What is the storage condition of Valganciclovir Q: What are the applications of Valganciclovir

175865-60-8

175680-60-8

C14H22N6O5

API