N-METHOXY-N-METHYL(TRIPHENYL-PHOSPHORANYLIDENE)ACETAMIDE

Product Name: N-METHOXY-N-METHYL(TRIPHENYL-PHOSPHORANYLIDENE)ACETAMIDE
CAS No.: 129986-67-0
Chemical Name: N-METHOXY-N-METHYL(TRIPHENYL-PHOSPHORANYLIDENE)ACETAMIDE
Synonyms: RMA-354;N-METHOXY-N-METHYL(TRIPHENYL-PHOSPHORANYLIDENE)ACETAMIDE;N-METHOXY-N-METHYL-2-(TRIPHENYLPHOSPHORANYLIDENE)ACETAMIDE;(N-methoxymethylaminocarbonylmethylene)triphenylphosphoran;N-Methoxy-N-methyl(triphenylphosphoranylidene)acetamide 98%;N-methoxy-N-methyl-2-(triphenyl-l5-phosphanylidene)acetamide;[N-METHOXYMETHYLAMINOCARBONYLMETHYLENE]-TRIPHENYLPHOSPHORANE;N-methoxy-N-methyl-2-(triphenyl-l5-phosphaneylidene)acetamide;Acetamide, N-methoxy-N-methyl-2-(triphenylphosphoranylidene)-;N-Methoxy-N-methyl-2-(triphenylphosphoranylidene)acetamide, 98 %
CBNumber: CB8445261
Molecular Formula: C22H22NO2P
Formula Weight: 363.39
MOL File: 129986-67-0.mol

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N-METHOXY-N-METHYL(TRIPHENYL-PHOSPHORANYLIDENE)ACETAMIDE Property

Melting point:: 183 °C
Boiling point:: 495.6±28.0 °C(Predicted)
Density: 1.18±0.1 g/cm3(Predicted)
storage temp.: -20°C Freezer, Under inert atmosphere
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Solid
color: Off White to Pale Yellow
BRN: 4198472
InChI: 1S/C22H22NO2P/c1-23(25-2)22(24)18-26(19-12-6-3-7-13-19,20-14-8-4-9-15-20)21-16-10-5-11-17-21/h3-18H,1-2H3
InChIKey: DGBLSOOPDBHHRX-UHFFFAOYSA-N
SMILES: CON(C)C(=O)C=P(c1ccccc1)(c2ccccc2)c3ccccc3

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
F: 9
HS Code: 29241900
Storage Class: 11 - Combustible Solids
Hazard Classifications: Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 376876
Product name: N-Methoxy-N-methyl(triphenylphosphoranylidene)acetamide
Purity: 98%
Packaging: 5g
Price: $135
Updated: 2025/07/31

Sigma-Aldrich

Product number: 376876
Product name: N-Methoxy-N-methyl(triphenylphosphoranylidene)acetamide
Purity: 98%
Packaging: 25g
Price: $631
Updated: 2025/07/31

TRC

Product number: M337775
Product name: N-Methoxy-N-methyl-2-(triphenylphosphoranylidene)acetamide
Packaging: 100mg
Price: $55
Updated: 2021/12/16

TRC

Product number: M337775
Product name: N-Methoxy-N-methyl-2-(triphenylphosphoranylidene)acetamide
Packaging: 500mg
Price: $100
Updated: 2021/12/16

Matrix Scientific

Product number: 089543
Product name: N-Methoxy-N-methyl-2-(triphenylphosphoranylidene)-acetamide
Packaging: 5g
Price: $103
Updated: 2021/12/16

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N-METHOXY-N-METHYL(TRIPHENYL-PHOSPHORANYLIDENE)ACETAMIDE Chemical Properties,Usage,Production

Chemical Properties

White to off-white powder

Uses

Reactant for:

Synthesis of electron-deficient alkenes via stereoselective olefination of N-sulfonyl imines
Phosphine-catalyzed asymmetric addition reactions
Cysteine-catalyzed enantioselective intramolecular Rauhut-Currier reaction
Wittig olefination
Synthesis of aigialomycin D, a Protein Kinase inhibitor and a potential anticancer agent

reaction suitability

reaction type: C-C Bond Formation

N-METHOXY-N-METHYL(TRIPHENYL-PHOSPHORANYLIDENE)ACETAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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N-METHOXY-N-METHYL(TRIPHENYL-PHOSPHORANYLIDENE)ACETAMIDE Suppliers

Belgium 1 China 39 France 2 Germany 1 Japan 1 Switzerland 1 United Kingdom 3 United States 6 Global 54

J & K SCIENTIFIC LTD.

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Energy Chemical

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Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

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Sigma-Aldrich

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Shanghai YuanYe Biotechnology Co., Ltd.

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129986-67-0, N-METHOXY-N-METHYL(TRIPHENYL-PHOSPHORANYLIDENE)ACETAMIDERelated Search:

(FORMYLMETHYLENE)TRIPHENYLPHOSPHORANE N-METHOXY-N-METHYL(TRIPHENYL-PHOSPHORANYLIDENE)ACETAMIDE

N-METHOXY-N-METHYL(TRIPHENYL-PHOSPHORANYLIDENE)ACETAMIDE

N-METHOXY-N-METHYL-2-(TRIPHENYLPHOSPHORANYLIDENE)ACETAMIDE

[N-METHOXYMETHYLAMINOCARBONYLMETHYLENE]-TRIPHENYLPHOSPHORANE

N-Methoxy-N-methyl-2-(triphenylphosphoranylidene)acetamide, 98 %

(N-methoxymethylaminocarbonylmethylene)triphenylphosphoran

N-Methoxy-N-methyl(triphenylphosphoranylidene)acetamide 98%

N-methoxy-N-methyl-2-(triphenyl-l5-phosphanylidene)acetamide

Acetamide, N-methoxy-N-methyl-2-(triphenylphosphoranylidene)-

N-methoxy-N-methyl-2-(triphenyl-l5-phosphaneylidene)acetamide

N-methoxy-N-methyl-2-(triphenyl-lambda5-phosphaneylidene)acetamide

<i>N</i>-Methoxy-<i>N</i>-methyl(triphenylphosphoranylidene)acetamide

RMA-354

129986-67-0

C6H53PCHCONOCH3CH3

C22H22NO2P

C-C Bond Formation

Olefination

Synthetic Reagents

Wittig Reagents