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FRAXIN

Product Name
FRAXIN
CAS No.
524-30-1
Chemical Name
FRAXIN
Synonyms
FRAXIN;Paviin;Fraxoside;FRAXIN(P);Fraxin-RM;FRAXIN WITH HPLC;FRAXIN USP/EP/BP;Fraxin (Fraxoside;Fraxetol8-glucoside;FRAXETIN-8-GLUCOSIDE
CBNumber
CB8445599
Molecular Formula
C16H18O10
Formula Weight
370.31
MOL File
524-30-1.mol
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FRAXIN Property

Melting point:
205-208°C
Boiling point:
420.23°C (rough estimate)
Density 
1.4066 (rough estimate)
refractive index 
1.5376 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO : 250 mg/mL (675.11 mM; Need ultrasonic)
form 
Solid
pka
6.99±0.20(Predicted)
color 
White
InChI
InChI=1/C16H18O10/c1-23-7-4-6-2-3-9(18)25-14(6)15(11(7)20)26-16-13(22)12(21)10(19)8(5-17)24-16/h2-4,8,10,12-13,16-17,19-22H,5H2,1H3/t8-,10-,12+,13-,16+/s3
InChIKey
CRSFLLTWRCYNNX-JAAAIXMONA-N
SMILES
C12OC(=O)C=CC=1C=C(OC)C(O)=C2O[C@H]1[C@H](O)[C@H]([C@H](O)[C@@H](CO)O1)O |&1:15,16,18,19,21,r|
LogP
-1.930 (est)
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Safety

WGK Germany 
3
RTECS 
DJ3091000
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHL89545
Product name
Fraxin
Purity
phyproof? Reference Substance
Packaging
10MG
Price
$277
Updated
2025/07/31
Sigma-Aldrich
Product number
80533
Product name
Fraxin
Purity
analytical standard
Packaging
10mg
Price
$388
Updated
2022/05/15
Cayman Chemical
Product number
28217
Product name
Fraxin
Packaging
5mg
Price
$110
Updated
2024/03/01
Cayman Chemical
Product number
28217
Product name
Fraxin
Packaging
50mg
Price
$648
Updated
2024/03/01
Cayman Chemical
Product number
28217
Product name
Fraxin
Packaging
10mg
Price
$195
Updated
2024/03/01
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FRAXIN Chemical Properties,Usage,Production

Chemical Properties

Slightly soluble in cold water, soluble in hot water and hot ethanol, practically insoluble in ether. Derived from the dried bark of the ash tree of the family Mulleinaceae, the pointed leaf ash or the persistent column ash

Uses

food and beverages

Definition

ChEBI: Fraxin is a beta-D-glucoside that is fraxetin attached to a beta-D-glucopyranosyl group at position 8 via a glycosidic linkage. It is a natural product isolated from the leaves of Fraxinus excelsior and exhibits potent hepatoprotective effects in vitro and in vivo. It has a role as a plant metabolite, an anti-inflammatory agent and a hepatoprotective agent. It is a beta-D-glucoside, a hydroxycoumarin and an aromatic ether. It is functionally related to a fraxetin.

in vivo

Fraxin (50 mg/kg, p.o.) significantly blocks the CCl4-induced elevation of ALT and AST. Fraxin (10 and 50 mg/kg, p.o.) significantly reduces the GSSG levels (1.7±0.3 and 1.5±0.2 nM/g liver, respectively) compared with the GSSG levels of the CCl4-treated group[1].

FRAXIN Preparation Products And Raw materials

Raw materials

Preparation Products

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FRAXIN Suppliers

China 227 France 2 Germany 2 India 1 Switzerland 1 United Kingdom 6 United States 19 Global 258
Extrasynthese
Tel
--
Fax
--
Email
info@extrasynthese.com
Country
France
ProdList
1333
Advantage
64
Carl Roth offre
Tel
--
Fax
--
Email
r.eckert@rothsochiel.fr
Country
France
ProdList
2361
Advantage
58
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View Lastest Price from FRAXIN manufacturers

Shanghai Standard Technology Co., Ltd.
Product
Fraxin 524-30-1
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2019-09-17
Career Henan Chemical Co
Product
FRAXIN 524-30-1
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
25kg
Release date
2019-07-12

524-30-1, FRAXINRelated Search:

2-Methoxyhydroquinone 2,3-DIMETHOXYTOLUENE METHYL BETA-D-GLUCOPYRANOSIDE FRAXIN 2-(Allyloxy)phenol 2-(3-METHYLPHENOXY)ETHANOL 2-(2-HYDROXYETHOXY)PHENOL 3-Phenoxy-1,2-propanediol 3,4-Dimethoxyphenol 2-ETHOXY-4-METHYLPHENOL 6-Hydroxycoumarin 2-Ethoxyphenol 2-METHOXYPHENYL ACETATE Guaifenesin 3-Butoxyphenol Isofraxidin METHYL BETA-D-GLUCOPYRANOSIDE HEMIHYDRATE 1,2,4-Benzenetriol

  • Fraxetol8-glucoside
  • 7,8-Dihydroxy-6-methoxycoumarin 8-β-D-glucopyranoside
  • Fraxetin 8-β-D-glucopyranoside
  • 8-(β-D-Glucopyranosyloxy)-7-hydroxy-6-methoxycoumarin monohydrate
  • 7,8-DIHYDROXY-6-METHOXYCOUMARIN-BETA-D-GLUCOPYRANOSIDE
  • FRAXETIN-8-GLUCOSIDE
  • FRAXETIN-8-O-GLUCOSIDE
  • FRAXIN
  • 8-(beta-D-glucopyranosyloxy)-7-hydroxy-6-methoxy-2H-1-benzopyran-2-one
  • FRAXIN WITH HPLC
  • 7,8-DIHYDROXY-6-METHOXYCOUMARIN-beta-D-GLUCOPYRANOSIDE hplc
  • 7,8-Dihydroxy-6-methoxycoumarin 8-β-D-glucopyranoside, 8-(β-D-Glucopyranosyloxy)-7-hydroxy-6-methoxycoumarin
  • 6-Methoxy-7-hydroxy-8-(β-D-glucopyranosyloxy)-2H-1-benzopyran-2-one
  • 8-(β-D-Glucopyranosyloxy)-7-hydroxy-6-methoxy-2H-1-benzopyran-2-one
  • 7-Hydroxy-6-methoxy-2-oxo-2H-chromen-8-yl beta-D-glucopyranoside
  • 7-Hydroxy-6-methoxy-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-2-one
  • Fraxoside
  • Paviin
  • FRAXIN(P)
  • Fraxin, 98%, from Fraxinus chinensis Roxb.
  • Fraxin (Fraxoside
  • 2H-1-Benzopyran-2-one, 8-(β-D-glucopyranosyloxy)-7-hydroxy-6-methoxy-
  • FRAXIN USP/EP/BP
  • 7-hydroxy-6-methoxy-8-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-2-one
  • 7-Hydroxy-6-methoxy-8-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2H-chromen-2-one
  • Fraxin-RM
  • Fraxin, 10 mM in DMSO
  • 8-(-D-glucopyranosyloxy)-7-hydroxy-6-methoxy-2H-1-benzopyran-2-one
  • 524-30-1
  • C16H18O10
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
  • Coumarins