Testosterone enanthate

Indications and Usage Drug Metabolism Clinical Research Adverse reactions

Product Name: Testosterone enanthate
CAS No.: 315-37-7
Chemical Name: Testosterone enanthate
Synonyms: Enanthate;TESTOSTERONE ENANTATE;Testosterone Enanthat;Testosterone Ethanate;Testostroval;Testosterone oenanthate;17-[(1-Oxoheptyl)oxy]androst-4-en-3-one;Testosterone Enanthate (Test e ,TE)-1 gram(2);Factory hot selling Testosterone Enanthate cas315-37-7 CAS NO.315-37-7;Everone
CBNumber: CB8448727
Molecular Formula: C26H40O3
Formula Weight: 400.59
MOL File: 315-37-7.mol

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Testosterone enanthate Property

Melting point:: 34-39°C
alpha: 77 º
Boiling point:: 463.22°C (rough estimate)
Density: 1.0562 (rough estimate)
refractive index: 1.4700 (estimate)
storage temp.: 2-8°C
solubility: Practically insoluble in water, very soluble in anhydrous ethanol, freely soluble in fatty oils.
InChI: InChI=1/C26H40O3/c1-4-5-6-7-8-24(28)29-23-12-11-21-20-10-9-18-17-19(27)13-15-25(18,2)22(20)14-16-26(21,23)3/h17,20-23H,4-16H2,1-3H3/t20-,21-,22-,23-,25-,26-/s3
InChIKey: VOCBWIIFXDYGNZ-IXKNJLPQSA-N
SMILES: [C@@]12([H])CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]1(C)[C@H](CC[C@@]21[H])OC(=O)CCCCCC |&1:0,10,12,16,18,21,r|
CAS DataBase Reference: 315-37-7(CAS DataBase Reference)
NIST Chemistry Reference: Testosterone enanthate(315-37-7)

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Safety

Hazard Codes: T
Risk Statements: 45-63
Safety Statements: 53-22-36/37/39-45
WGK Germany: 3
RTECS: XA3080000
HS Code: 2937290000
Toxicity: man,TDLo,intramuscular,7519mg/kg/5W- (7519mg/kg),LUNGS, THORAX, OR RESPIRATION: DYSPNEA,New England Journal of Medicine. Vol. 308, Pg. 508, 1983.

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H350May cause cancer

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: T3006
Product name: Testosterone enanthate
Purity: analytical standard
Packaging: 1g
Price: $111
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1648004
Product name: Testosterone enanthate
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 200mg
Price: $532
Updated: 2024/03/01

Cayman Chemical

Product number: 22546
Product name: Testosterone Enanthate
Purity: ≥98%
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 22546
Product name: Testosterone Enanthate
Purity: ≥98%
Packaging: 5mg
Price: $93
Updated: 2024/03/01

Sigma-Aldrich

Product number: Y0001317
Product name: Testosterone enantate for system suitability
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: y0001317
Price: $150
Updated: 2024/03/01

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Testosterone enanthate Chemical Properties,Usage,Production

Indications and Usage

Testosterone enanthate is a type of androgen drug, and it is a synthetic compound of testosterone proprionate and testosterone enantate. Its effects are the same as those of testosterone acetate, which include promoting the development of male sex organs and secondary sex characteristics and resisting estrogen. It also has protein assimilating effects, which allow it to help muscle growth and weight gain. Testosterone enanthate can inhibit the pituitary gland and promote sex hormone secretion, thus decreasing the endogenous testosterone secreted by Leydig cells, which achieves the purpose of stopping spermatogenesis.
Testosterone enanthate can be used as a long-term male birth control drug. It is clinically used to treat male hypogonadism and gonadal insufficiency, sex organ hypogenesis, infertility, eunuchism, and cryptorchidism. It can also be used to treat female dysfunctional uterine bleeding, menopausal syndrome, breast cancer and uterine cancer. It can also treat cirrhosis, aplastic anemia, osteoporosis and other consumptive diseases.

Drug Metabolism

After injection, it creates a blood concentration higher than the physiological level, and then blood concentration decreases rapidly.

Clinical Research

In a trial that injected monkeys with testosterone enanthate every week, the monkeys’ sperm cells began experiencing apoptosis in a week, with apoptosis rates peaking in the fifth week. A clinical trial with 308 participants also showed that testosterone enanthate’s birth-control effects are much more effective on Asian men than on Caucasian men, as over 95% of Asian men achieved azoospermia, while only 40-70% of Caucasian men did.
A trial of over 100 volunteers showed that weekly muscle injections of 250mg led to most men developing azoospermia or severe ogliospermia in 10 weeks, and that sperm count could recover after ceasing injection for a certain period of time. If the injection intervals are extended to over 10-12 days, even increasing dosage will not have desired effects. Testosterone enanthate only needs to be injected once a week, which is an advantage over testosterone acetate.

Adverse reactions

Large dosages or extended use can cause water and sodium retention and edema. Young women may exhibit virilism, with characteristics including deepened voice, hair growth, acne, clitoral hypertrophy, etc. Not to be used by patients with prostatic cancer or pregnant patients. Should be used with caution by patients with prostate hypertrophy and liver and kidney dysfunction. When treating breast cancer, drug usage should be stopped immediately if hypercalcemia is detected.

Description

Testosterone enanthate (Item No. 22546) is an analytical reference standard categorized as an anabolic androgenic steroid. It is an ester of the naturally occurring androgen, testosterone (Item Nos. 15645 | ISO60154) with a longer half-life. Formulations containing testosterone enanthate have been tested for use in hypogonadism and as a potential male contraceptive. Formulations containing it have been associated with higher levels of total cholesterol, low density lipoproteins, and triglycerides and lower levels of high density lipoproteins. Anabolic steroids, including testosterone enanthate, have been used to enhance physical performance in racehorses and athletes, and methods to detect steroids, their derivatives, and their metabolites have been developed. This product is intended for research and forensic applications.

Chemical Properties

White or yellowish-white, crystalline powder.

Originator

Delatestryl,Squibb,US,1954

Uses

Testosterone Enanthate is a derivative of testosterone (T155000), the principal hormone of the testes, produced by the interstitial cells.

Definition

ChEBI: Testosterone enanthate is a heptanoate ester and a sterol ester. It has a role as an androgen. It is functionally related to a testosterone.

Manufacturing Process

A mixture of testosterone, pyridine and oenanthic acid anhydride is heated for 1 1/2 hours to 125°C. The cooled reaction mixture is decomposed with water while stirring and cooling. After prolonged standing at a temperature below room temperature, the whole is extracted with ether and the ethereal solution is washed consecutively with dilute sulfuric acid, water, 5% sodium hydroxide solution, and again with water. The crude ester remaining on evaporation of the dried ether solution, after recrystallization from pentane, melts at 36° to 37.5°C.

Therapeutic Function

Androgen

Testosterone enanthate Preparation Products And Raw materials

Raw materials

Preparation Products

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Testosterone enanthate Suppliers

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View Lastest Price from Testosterone enanthate manufacturers

CONTIDE BIOTECH CO.,LTD

Product: Testosterone Enanthate 315-37-7
Price: US $0.00/G
Min. Order: 1G
Purity: 99%
Supply Ability: 20
Release date: 2024-04-11

hebei hongtan Biotechnology Co., Ltd

Product: testosterone enanthate 315-37-7
Price: US $30.00-10.00/kg
Min. Order: 1kg
Purity: 99.99%
Supply Ability: 200ton
Release date: 2024-03-14

hebei hongtan Biotechnology Co., Ltd

Product: Testosterone Enanthate 315-37-7
Price: US $30.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 2000kg
Release date: 2024-05-15

315-37-7, Testosterone enanthateRelated Search:

Testosterone cypionate Testosterone decanoate Testosterone undecanoate 17-Methyltestosterone Testosterone propionate Testosterone Testosterone acetate Testosterone phenylpropionate Testosterone isocaproate δ-5-Testosterone 3,17-dienantate Testosterone decanoate for system suitability testosterone ketolaurate Heptanoic acid 1-Testosterone enanthate heptanoate TESTOSTERONE PALMITATE-D31 4-HYDROXYTESTOSTERONE DECANOATE Testosterone enanthate

17-[(1-Oxoheptyl)oxy]androst-4-en-3-one

17-Hydroxyandrost-4-en-3-one, 17-heptanoate

3-Oxoandrost-4-en-17-yl heptanoate

99% Testosterone Enanthate powder

Factory hot selling Testosterone Enanthate cas315-37-7 CAS NO.315-37-7

99% Testosterone Enanthate powder CAS NO.315-37-7

Andro L.A. 200

Androst-4-en-3-one, 17-[(1-oxoheptyl)oxy]-, (17beta)-

Androst-4-en-3-one, 17beta-hydroxy-, heptanoate

Androtardyl

Atlatest

component of Androgyn l.a.

component of Deladumone

component of Ditate

component of Mal-O-Fem L.A

Delatest

Depo-Testro Med

Everone

Exten test

Heptanoic acid, ester with testosterone

heptanoicacid,esterwithtestosterone

Malogen L.A.

Malogen L.A.200

malogenl.a.200

NSC-17591

Orquisteron-E

reposotmd

Reposo-TMD

Testanthate

Testate

testenate

TESTOSTERONEENANTHATE,USP

[(8R,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl] heptanoate

17b-Enanthoxyandrost-4-en-3-one

17b-Hydroxyandrost-4-en-3-one enanthate

4-Androsten-3-one 17b-enanthate

Androst-4-en-3-one, 17-[(1-oxoheptyl)oxy]-, (17b)- (9CI)

Primoteston-Depot

Testosterone, heptanoate (6CI, 8CI)

Testosterone Enanthate Injection

4-Androsten-17β-ol-3-one 17-enanthate

Testosterone 17β-heptanoate

Testosterone Enanthate CIII (200 mg)

Testosterone Enanthate (CIII), BP, EP

Testosterone Heptanoate-d5

Testosterone-d3 Heptanoate

17β-Hydroxy-4-androsten-3-one 17-enanthate, 4-Androsten-17β-ol-3-one 17-enanthate, Testosterone 17β-heptanoate

17β-(Heptanoyloxy)androst-4-en-3-one

3-Oxoandrost-4-en-17β-ol heptanoate

Enanthic acid testosterone

Atlates

enanthic acid [(8R,9S,10R,13S,14S,17S)-3-keto-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl] ester

(8R,9S,10R,13S,14S,17S)-10,13-diMethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl heptanoate

Androst-4-en-3-one,17-[(1-oxoheptyl)oxy]-, (17b)-

Testosterone Enanthat

Testosterone enanthate Testosterone heptanoate

Testosterone enantate for system suitability

Testosterone enantate for peak identification