TETRAHYDRO-3-FURANMETHANOL
Uses- Product Name
- TETRAHYDRO-3-FURANMETHANOL
- CAS No.
- 15833-61-1
- Chemical Name
- TETRAHYDRO-3-FURANMETHANOL
- Synonyms
- (TETRAHYDROFURAN-3-YL)METHANOL;3-tetrahydrofuranmethanol;3-Hydroxymethyl-THF;RARECHEM AL BD 0888;(3-Oxolanyl)Methanol;Tetrahydro-3-furanmethano;TETRAHYDRO-3-FURANMETHANOL;3-FuranMethanol,tetrahydro-;Tetrahydro-3-furanylmethanol;Tetrahydrofuran-3-ylmetha...
- CBNumber
- CB8457107
- Molecular Formula
- C5H10O2
- Formula Weight
- 102.13
- MOL File
- 15833-61-1.mol
TETRAHYDRO-3-FURANMETHANOL Property
- Boiling point:
- 76-77 °C4 mm Hg(lit.)
- Density
- 1.061 g/mL at 25 °C(lit.)
- refractive index
- n20/D 1.456(lit.)
- Flash point:
- 208 °F
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- form
- liquid
- pka
- 14.81±0.10(Predicted)
- color
- Colourless
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 340588
- Product name
- Tetrahydro-3-furanmethanol
- Purity
- contains 250 ppm BHT as inhibitor, 99%
- Packaging
- 1g
- Price
- $47.1
- Updated
- 2023/01/07
- Product number
- 340588
- Product name
- Tetrahydro-3-furanmethanol
- Purity
- contains 250 ppm BHT as inhibitor, 99%
- Packaging
- 5g
- Price
- $194
- Updated
- 2023/01/07
- Product number
- T2800
- Product name
- (Tetrahydrofuran-3-yl)methanol
- Purity
- min. 98.0 %
- Packaging
- 5G
- Price
- $96
- Updated
- 2025/07/31
- Product number
- T2800
- Product name
- (Tetrahydrofuran-3-yl)methanol
- Purity
- min. 98.0 %
- Packaging
- 25G
- Price
- $287
- Updated
- 2025/07/31
- Product number
- 340588
- Product name
- Tetrahydro-3-furanmethanol
- Purity
- contains 250 ppm BHT as inhibitor, 99%
- Packaging
- 25g
- Price
- $281
- Updated
- 2023/01/07
TETRAHYDRO-3-FURANMETHANOL Chemical Properties,Usage,Production
Uses
3-Tetrahydrofuranmethanol is an alcoholic organic compound that can be used as a pharmaceutical intermediate.
Chemical Properties
Colorless viscous liquid
General Description
Tetrahydro-3-furanmethanol was the main product formed during hydrolysis of 1,3-dioxolane compounds.
Synthesis
6482-32-2
124391-75-9
1) To a 500 mL four-necked reaction flask was added 152 g of diethyl malonate (0.95 mol) and 27.6 g of an isopropanol solution of 20% sodium isopropoxide (sodium isopropoxide content was 20%), and the reaction temperature was maintained at 25°C to 28°C. 46.5 g of 2-bromoethanol (0.372 mol) was started to be added dropwise, and then the temperature was raised to 50°C and the reaction was kept at a constant temperature for 1.5 h. After the reaction was completed, the solvent was removed by a rotary evaporator at less than 75°C and the reaction was completed. Upon completion of the reaction, the solvent was removed by rotary evaporator at less than 75°C to give diethyl 2-hydroxyethylmalonate, a colorless oily liquid with 97% purity (GC) and 94% yield. 2) To a 500 mL four-neck reaction flask was added 66.7 g of diethyl 2-hydroxyethyl malonate (0.317 mol) and 76.1 g of 20% sodium hydroxide solution, heated to 45°C, and reacted for 2 hours. After cooling to 25°C, 20% hydrochloric acid was added to adjust the pH to 6-7, then evaporated under reduced pressure at 80°C and filtered to obtain a colorless oily liquid 2-hydroxyethylmalonic acid 47.4 g (0.305 mol), purity 95% (GC), yield 96%. 3) To an autoclave was added 47.4 g of 2-hydroxyethylmalonic acid (0.305 mol), 50 g of water and 2.3 g of Cu/SiO2 catalyst. After purging the reaction vessel with nitrogen for 3-5 times, the reaction was carried out at 240°C for 4 hours. Upon completion of the reaction, the catalyst was removed by filtration to afford 36.2 g (0.280 mol) of 2-hydroxymethyl-1,4-butanediol as a colorless or light yellow oil with 96% purity (GC) and 95% yield. 4) To a 500 mL reaction flask equipped with a reflux condenser was added 36.2 g of 2-hydroxymethyl-1,4-butanediol (0.280 mol), 150 g of toluene and 1.6 g of methanesulfonic acid. After completion of the reaction, the solvent was removed by distillation under reduced pressure to afford 25.2 g (S)-tetrahydrofuran-3-methanol (0.192 mol) as a pale yellow oil with 95% purity (GC) and 86% yield.
References
[1] Patent: CN105254598, 2016, A. Location in patent: Paragraph 0007; 0022
[2] Patent: CN103709126, 2018, B. Location in patent: Paragraph 0029; 0035; 0036; 0044
[3] Patent: CN104193701, 2016, B. Location in patent: Paragraph 0023
TETRAHYDRO-3-FURANMETHANOL Preparation Products And Raw materials
Raw materials
Preparation Products
TETRAHYDRO-3-FURANMETHANOL Suppliers
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44801
- Advantage
- 61
- Tel
- 13817811078
- Fax
- 86-021-50426522,50426273
- sales@jingyan-chemical.com
- Country
- China
- ProdList
- 9976
- Advantage
- 60
- Tel
- 13526569071
- sales@leadmedpharm.com
- Country
- China
- ProdList
- 7892
- Advantage
- 64
- Tel
- 17702719238 18971495150;
- sales@sun-shinechem.com
- Country
- China
- ProdList
- 1077
- Advantage
- 64
- Tel
- 021-58099652-8005 13585536065
- Fax
- 021-58099609
- bin.wu@shlschem.com
- Country
- China
- ProdList
- 9883
- Advantage
- 59
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
- Country
- China
- ProdList
- 42934
- Advantage
- 64
- Tel
- 86-0571-85151182
- Fax
- 86-0571-85151182
- Country
- China
- ProdList
- 5691
- Advantage
- 66
- Tel
- 4009903999 13355009207
- Fax
- 0539-6365991
- 3007715519@qq.com
- Country
- China
- ProdList
- 18729
- Advantage
- 57
- Tel
- Please Send Email 18652950785
- Fax
- 025-87193546
- chemweiao@163.com
- Country
- China
- ProdList
- 4378
- Advantage
- 65
- Tel
- 15026939015
- Fax
- QQ：1498609168
- michael.liu16@yahoo.com
- Country
- China
- ProdList
- 97
- Advantage
- 52
- Tel
- 021-56491756 13512199871
- Fax
- 021-5649-1756
- 2819742715@qq.com
- Country
- China
- ProdList
- 4000
- Advantage
- 55
- Tel
- 150-2103-5486 18017383231
- Fax
- qq：2817624287
- 983544897@qq.com
- Country
- China
- ProdList
- 9342
- Advantage
- 55
- Tel
- 400-6206333 13167063860
- Fax
- 021-50323701
- anhua.mao@aladdin-e.com
- Country
- China
- ProdList
- 25003
- Advantage
- 65
- Tel
- 86-0755-86635001
- Fax
- 86-0755-22642228
- cantotech@126.com
- Country
- China
- ProdList
- 4566
- Advantage
- 55
- Tel
- +86-021-50935922
- Fax
- +86-021-33847795
- Country
- China
- ProdList
- 7865
- Advantage
- 55
- Tel
- 0512-66585217 13962137180
- Fax
- 0512-82177549
- sales@ryanchem.com
- Country
- China
- ProdList
- 384
- Advantage
- 55
- Tel
- 021-68367562 15002147577;
- Fax
- 021-68369562
- sales@haoyunchem.com
- Country
- China
- ProdList
- 457
- Advantage
- 55
- Tel
- 031185291771 13832391721
- Fax
- 0311-67305698
- yaofeng2005@163.com
- Country
- China
- ProdList
- 978
- Advantage
- 58
- Tel
- 0512-56316828 4008675858
- Fax
- +86-512-56316826
- sales@amateksci.com
- Country
- China
- ProdList
- 9874
- Advantage
- 55
- Tel
- 0554-2106669
- Fax
- 0554-2666215
- sales1@kedichem.com
- Country
- China
- ProdList
- 4924
- Advantage
- 55
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 39966
- Advantage
- 60
- Tel
- 021-021-56795766
- Fax
- +86-21-56795266
- sales@worldyachem.com
- Country
- China
- ProdList
- 9476
- Advantage
- 58
- Tel
- 400-1166-196 13458535857
- Fax
- QQ：800101999
- cdhxsj@163.com
- Country
- China
- ProdList
- 13350
- Advantage
- 58
- Tel
- 0510-85629785 18013409632
- Fax
- 051085625359
- sales@reading-chemicals.com
- Country
- China
- ProdList
- 15178
- Advantage
- 58
- Tel
- +86 (0)21 51320687 51371369 1744605818
- Fax
- +86 (0)21 51371369
- Country
- China
- ProdList
- 1578
- Advantage
- 58
- Tel
- 19943855286
- Fax
- 0371-53392065
- triz-4@trizpharma.cn
- Country
- China
- ProdList
- 1936
- Advantage
- 56
- Tel
- 021-60345187 13671753212
- Fax
- 021-34702061
- lzz841106@aliyun.com
- Country
- China
- ProdList
- 10263
- Advantage
- 55
- Tel
- 13391076197
- tombiopharma@163.com
- Country
- China
- ProdList
- 4987
- Advantage
- 55
- Tel
- +86 (21) 61124340
- Fax
- +86 (21) 6129-4103
- Country
- China
- ProdList
- 9756
- Advantage
- 58
- Tel
- 021-60455363 18019463053
- Fax
- 50966098
- sales@coolpharm.com
- Country
- China
- ProdList
- 12346
- Advantage
- 58
- Tel
- 027-59599241 18871490274
- Fax
- 027-59599241
- 1400878000@qq.com
- Country
- China
- ProdList
- 9858
- Advantage
- 58
- Tel
- Fax
- -
- xg01_gj@163.com
- Country
- China
- ProdList
- 9484
- Advantage
- 50
- Tel
- 0571-82896630 18969958410
- sales_hz@milestonepharmtech.com
- Country
- China
- ProdList
- 4894
- Advantage
- 55
- Tel
- 021-61415566 800-8193336
- orderCN@merckgroup.com
- Country
- China
- ProdList
- 51395
- Advantage
- 80
- Tel
- 028-85434334 18108076537
- Fax
- QQ：245797092
- market@gianthx.com
- Country
- China
- ProdList
- 4505
- Advantage
- 56
- Tel
- Fax
- -
- eric_feng1954@126.com
- Country
- China
- ProdList
- 9248
- Advantage
- 55
- Tel
- 028-88469284 18000562381
- rzbtsj@163.com
- Country
- China
- ProdList
- 9951
- Advantage
- 56
- Tel
- 0571-88937695 88937835 13606537248
- sales@chemspon.com
- Country
- China
- ProdList
- 249
- Advantage
- 58
- Tel
- 025-87193546 18652950785
- Fax
- 025-87193546
- chemweiao@163.com
- Country
- China
- ProdList
- 9021
- Advantage
- 60
- Tel
- 021-61312847; 18021002903
- Fax
- QQ:3008007432
- 3008007409@qq.com
- Country
- China
- ProdList
- 71826
- Advantage
- 60
- Tel
- 02781293128
- orders@biochemsafebuy.com
- Country
- China
- ProdList
- 9923
- Advantage
- 55
- Tel
- 021-20242659 18930833303
- Fax
- +86 (21) 2024-2659
- Sales@changyanchem.cn
- Country
- China
- ProdList
- 5001
- Advantage
- 55
- Tel
- 025-83453382-8005
- Fax
- 025-83453382
- sale@parabiochem.com
- Country
- China
- ProdList
- 9595
- Advantage
- 55
- Tel
- 571-89925085
- Fax
- 0086-571-89925065
- sales@amadischem.com
- Country
- China
- ProdList
- 131957
- Advantage
- 58
- Tel
- 0751-2886750 13927877953
- Fax
- 0751-2886750
- 3005811397@qq.com
- Country
- China
- ProdList
- 13305
- Advantage
- 58
- Tel
- 18621295758
- Fax
- -QQ:1449085402
- 1449085402@qq.com
- Country
- China
- ProdList
- 1817
- Advantage
- 55
- Tel
- 17792809151
- Fax
- 18872220797
- 2355916837@ycphar.com
- Country
- China
- ProdList
- 6133
- Advantage
- 55
- Tel
- 025-52343882 18112933882
- Fax
- 025-52343882
- sales@kldbio.com
- Country
- China
- ProdList
- 2019
- Advantage
- 55
- Tel
- 13127280945
- 285424065@qq.com
- Country
- China
- ProdList
- 9976
- Advantage
- 55
- Tel
- 021-2221346380 021-54220652 17701603001
- Fax
- QQ:2221346380
- bankpharma@163.com
- Country
- China
- ProdList
- 423
- Advantage
- 58
View Lastest Price from TETRAHYDRO-3-FURANMETHANOL manufacturers
- Product
- TETRAHYDRO-3-FURANMETHANOL 15833-61-1
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-19
- Product
- TETRAHYDRO-3-FURANMETHANOL 15833-61-1
- Price
- US $9.00/KG
- Min. Order
- 1KG
- Purity
- 99.9
- Supply Ability
- 1 ton
- Release date
- 2024-08-21
- Product
- Tetrahydro-3-furanylmethanol 15833-61-1
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10