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TAUROURSODEOXYCHOLIC ACID SODIUM SALT

Product Name
TAUROURSODEOXYCHOLIC ACID SODIUM SALT
CAS No.
35807-85-3
Chemical Name
TAUROURSODEOXYCHOLIC ACID SODIUM SALT
Synonyms
TUDC;auroursodeoxycholate Sodium;SODIUM TAUROURSODEOXYCHOLATE;Ursodeoxycholyltaurine sodium;Tauroursodeoxycholate (Sodium);Urosodeoxycholic Acid Impurity 25;Taurocursodeoxycholic acid sodium;Sodium Tauroursodeoxycholate (TUDC);Sodium tauroursodesoxycholate, >=97%;TAUROURSODEOXYCHOLIC ACID SODIUM SALT
CBNumber
CB8459121
Molecular Formula
C26H46NNaO6S
Formula Weight
523.7
MOL File
35807-85-3.mol
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TAUROURSODEOXYCHOLIC ACID SODIUM SALT Property

Melting point:
173-175°C
alpha 
+40～+50°(D/20℃)
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
solubility 
DMSO (Slightly, Heated), Ethanol (Slightly, Sonicated), Methanol (Slightly)
form 
Solid
color 
Off-White to Pale Beige
Water Solubility 
water: 100mg/mL
InChIKey
WSSCRQYICWZEFG-SXXADWEANA-N
SMILES
C[C@]12CC[C@]3([H])[C@]4(CC[C@@H](O)C[C@@]4([H])C[C@H](O)[C@@]3([H])[C@]1([H])CC[C@]2([H])[C@H](C)CCC(=O)NCCS(O)(=O)=O)C.[NaH] |&1:1,4,6,9,12,15,17,19,23,25,r|
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Safety

WGK Germany 
2
RTECS 
KI7372500
HS Code 
2924297099
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P313Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T0266
Product name
Sodium tauroursodeoxycholate
Packaging
500mg
Price
$587
Updated
2025/07/31
Sigma-Aldrich
Product number
T0266
Product name
Sodium tauroursodeoxycholate
Packaging
1g
Price
$945
Updated
2025/07/31
Sigma-Aldrich
Product number
580549
Product name
Tauroursodeoxycholic Acid, Sodium Salt
Purity
Tauroursodeoxycholic is a detergent useful for the solubilization of lipids and membrane-bound proteins.
Packaging
1 g
Price
$226
Updated
2025/07/31
Sigma-Aldrich
Product number
580549
Product name
Tauroursodeoxycholic Acid, Sodium Salt
Purity
Tauroursodeoxycholic is a detergent useful for the solubilization of lipids and membrane-bound proteins.
Packaging
5 g
Price
$768
Updated
2025/07/31
Cayman Chemical
Product number
9003379
Product name
Tauroursodeoxycholic Acid (sodium salt)
Packaging
1mg
Price
$25
Updated
2021/12/16
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TAUROURSODEOXYCHOLIC ACID SODIUM SALT Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

Tauroursodeoxycholic Acid Sodium Salt is a bile related salt for isolation of lipids and membrane-bound proteins. It is a sodium salt form of Tauroursodeoxycholic Acid which can be used in biological study of inhibition of alpha-naphthyl isothiocyanate-induced liver injury and bile acid cycle disruption by glycyrrhizin and glycyrrhetinic acid.

Uses

Sodium tauroursodeoxycholate has been used in a study to assess whether ER stress is involved in palmitic acid upregulation (PA). It has also been used in a study to investigate its effect on Estradiol-17β-D-glucuronide (E-17G) induced cholestasis in female rats.

Uses

Tauroursodeoxycholate inhibits human cholangiocarcinoma growth via Ca2+-, PKC-, and MAPK-dependent pathways.

General Description

Sodium tauroursodeoxycholate is a bile salt which is naturally present in the small bowel.

in vivo

The effects of Tauroursodeoxycholate (TUDCA) on proliferation and apoptosis of VSMCs in vivo are examined using immunohistochemistry. Tauroursodeoxycholate (10, 50, and 100 mg/kg) increases the caspase 3 activity of injured tissues in a dose-dependent manner, indicating that Tauroursodeoxycholate induces apoptosis of VSMCs in the neointima. Using the injured tissues, further examination and comparison of the phosphorylation level of ERK and MMP-9 expression is performed at 1 week after injury, compared with normal controls. Balloon injury increased both the phosphorylation of ERK and expression of MMP-9 in the tissues. Tauroursodeoxycholate (10, 50, and 100 mg/kg) inhibits phosphorylation of ERK and MMP-9 expression in a dose-dependent manner[1]. Tauroursodeoxycholate (TUDCA) is a hydrophilic bile acid. Tauroursodeoxycholate as a cytoprotective agent improves liver function and can prevent hepatocellular carcinoma by reducing ER stress and apoptosis. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3, caspase-12, C/EBP homologous protein, c-Jun N-terminal kinase (JNK), activating transcription factor 4 (ATF4), X-box binding protein (XBP), and eukaryotic initiation factor 2α (eIF2α) in Ang II induced ApoE-/- mice (p<0.05). Tauroursodeoxycholate reduces Angiotensin (Ang) II induced abdominal aortic aneurysm (AAA)? formation in ApoE-/- mice. Tauroursodeoxycholate is used at a dose of 0.5 g/kg/day in treating Ang II induced ApoE-/- mice (ER stress inhibitor group). Systolic blood pressure (141.3±5.6 mmHg vs 145.9±8.9 mmHg; p>0.05) and total cholesterol levels (663.6±88.7 mg/dL vs 655.7±65.4 mg/dL; p>0 .05) do not differ between the AAA model group and Tauroursodeoxycholate group. In addition, maximum aortic diameter is significantly smaller in those in Tauroursodeoxycholate group compared with those in the AAA model group (0.95±0.03 mm vs 1.79±0.04 mm; p<0.05). AAA lesion areas are also smaller in those in Tauroursodeoxycholate group than in those in the AAA model group (0.37±0.03 mm2 vs 1.51±0.06 mm2; p<0.05)[2].

IC 50

ERK; Caspase-3; Caspase-12; Human Endogenous Metabolite

TAUROURSODEOXYCHOLIC ACID SODIUM SALT Preparation Products And Raw materials

Raw materials

Preparation Products

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TAUROURSODEOXYCHOLIC ACID SODIUM SALT Suppliers

Canada 1 China 201 China Hong Kong 1 India 6 Japan 2 Switzerland 1 United Kingdom 2 United States 18 Global 232
Xunteng International Trading Co.,Limited
Tel
Country
China Hong Kong
ProdList
878
Advantage
55
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View Lastest Price from TAUROURSODEOXYCHOLIC ACID SODIUM SALT manufacturers

HANGZHOU HAILAN CHEMICAL CO.,LTD.
Product
TAUROURSODEOXYCHOLIC ACID SODIUM SALT 35807-85-3
Price
US $0.00/kg
Min. Order
1kg
Purity
99%min
Supply Ability
2000KGS
Release date
2025-10-24
Anhuyan (Hainan) Biotechnology Co., LTD
Product
TAUROURSODEOXYCHOLIC ACID SODIUM SALT 35807-85-3
Price
US $1.00/g
Min. Order
1g
Purity
99.99
Supply Ability
100000
Release date
2025-06-05
Shaanxi Xianhe Biotech Co., Ltd
Product
Sodium tauroursodeoxycholate 35807-85-3
Price
US $0.00/KG
Min. Order
1KG
Purity
0.99
Supply Ability
1000KG
Release date
2025-04-21

35807-85-3, TAUROURSODEOXYCHOLIC ACID SODIUM SALTRelated Search:

Tauroursodeoxycholic acid TAUROLITHOCHOLIC ACID SODIUM SALT Taurodeoxycholic acid sodium salt TAUROHYODEOXYCHOLIC ACID SODIUM SALT Sodium taurocholate β-D-Glucopyranosiduronic acid, (3α,5β,7β)-7-hydroxy-24-oxo-24-[(2-sulfoethyl)amino]cholan-3-yl, dipotassium salt (9CI) BHTRKEVKTKCXOH-UYRINQEQSA-N β-D-Glucopyranosiduronic acid, (3α,5β,7α)-7-hydroxy-24-oxo-24-[(2-sulfoethyl)amino]cholan-3-yl, dipotassium salt (9CI) Taurochenodeoxycholic acid TAUROCHENODEOXYCHOLIC ACID SODIUM SALT Sodium cholate Ursodeoxycholic acid 5BETA-CHOLANIC ACID

  • 3ALPHA,7BETA-DIHYDROXY-5BETA-CHOLAN-24-OIC ACID N-[2-SULFOETHYL]AMIDE SODIUM SALT
  • 5-BETA-CHOLANIC ACID-3-ALPHA, 7-BETA-DIOL N-(2-SULPHOETHYL)-AMIDE SODIUM SALT
  • 5BETA-CHOLAN-24-OIC ACID N-[2-SULFOETHYL]AMIDE-3ALPHA,7BETA-DIOL SODIUM SALT
  • SODIUM TAUROURSODEOXYCHOLATE
  • TAURO-URSODEOXYCHOLIC ACID, MONOSODIUM SALT
  • TAUROURSODEOXYCHOLIC ACID SODIUM SALT
  • Sodium tauroursodesoxycholate, >=97%
  • 2-(3α,7β-Dihydroxy-24-oxo-5β-cholan-24-yl)amino-1-ethanesulfonic acid sodium salt
  • 2-[(3α,7β-Dihydroxy-24-oxo-5β-cholane-24-yl)amino]-1-ethanesulfonic acid sodium salt
  • 2-[[(3α,5β,7β)-3,7-Dihydroxy-24-oxocholan-24-yl]amino]ethanesulfonic acid sodium salt
  • Tauroursodeoxycholic Acid SodiuM Salt (90%)
  • sodium,2-[[(4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]ethanesulfonate
  • Tauroursodeoxycholate (Sodium)
  • Sodium Tauroursodeoxycholate (TUDC)
  • TUDC
  • Ethanesulfonic acid,2-[[(3a,5b,7b)-3,7-dihydroxy-24-oxocholan-24-yl]amino]-, sodium salt (1:1)
  • TAUROURSODEOXYCHOLIC ACID SODIUM SALTr
  • auroursodeoxycholate Sodium
  • Sodium Tauroursodeoxycholate Sodium Salt
  • TAUROURSODEOXYCHOLIC ACID SODIUM SALT CAS: 35807-85-3
  • Sodium Tauroursodeoxycholate (TUDCA Sodium) extrapure, 98%
  • Ursodeoxycholyltaurine sodium
  • Urosodeoxycholic Acid Impurity 25
  • Sodium 2-((R)-4-((3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)ethane-1-sulfonate
  • Taurocursodeoxycholic acid sodium
  • Tauroursodeoxycholate sodium, 10 mM in DMSO
  • 35807-85-3
  • Chiral Reagents
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Steroids
  • 35807-85-3