3,5-DIHYDROXY-7-METHOXY-2-(4-METHOXY-PHENYL)-CHROMEN-4-ONE

Product Name: 3,5-DIHYDROXY-7-METHOXY-2-(4-METHOXY-PHENYL)-CHROMEN-4-ONE
CAS No.: 15486-33-6
Chemical Name: 3,5-DIHYDROXY-7-METHOXY-2-(4-METHOXY-PHENYL)-CHROMEN-4-ONE
Synonyms: 5-Dihydroxy-4';Einecs 239-513-1;7-dimethoxyflavone;7-O-Dimethylkaempferol;4'-O,7-O-Dimethylkaempferol;Kaempferol-4',7-dimethylether;Kaempferol 4',7-dimethyl ether;KAEMPFEROL-7,4'-DIMETHYL ETHER;Kaempferol 7,4'-dimethyl ether;Kaempferol-7,4''-dimethyl ether
CBNumber: CB8459237
Molecular Formula: C17H14O6
Formula Weight: 314.29
MOL File: 15486-33-6.mol

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3,5-DIHYDROXY-7-METHOXY-2-(4-METHOXY-PHENYL)-CHROMEN-4-ONE Property

storage temp.: 2-8°C
form: Solid
color: Light yellow to yellow
LogP: 3.247 (est)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biosynth Carbosynth

Product number: FK65584
Product name: Kaempferol-7,4'-dimethyl ether
Packaging: 1mg
Price: $50
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FK65584
Product name: Kaempferol-7,4'-dimethyl ether
Packaging: 2mg
Price: $75
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FK65584
Product name: Kaempferol-7,4'-dimethyl ether
Packaging: 5mg
Price: $100
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FK65584
Product name: Kaempferol-7,4'-dimethyl ether
Packaging: 10mg
Price: $180
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FK65584
Product name: Kaempferol-7,4'-dimethyl ether
Packaging: 25mg
Price: $375
Updated: 2021/12/16

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3,5-DIHYDROXY-7-METHOXY-2-(4-METHOXY-PHENYL)-CHROMEN-4-ONE Chemical Properties,Usage,Production

Uses

Kaempferol-7,4'-dimethyl ether is a PTP1B inhibitor, and also can inhibit the production of NO. Kaempferol-7,4'-dimethyl ether shows the inhibition rate of 46.1% at 100 μM. Kaempferol-7,4'-dimethyl ether inhibits PTP1B activity with IC50 value of 16.92 μM[1][2].

Definition

ChEBI: 7,4'-dimethylkaempferol is a dimethoxyflavone that is kaempferol in which the hydroxy groups at position 4' and 7 have been replaced by methoxy groups. It is a component of bee glue and has been isolated from several plant species including Betula exilis, Zingiber mekongense and Alpinia flabellata. It has a role as an antioxidant and a plant metabolite. It is a dimethoxyflavone, a dihydroxyflavone and a member of flavonols. It is functionally related to a kaempferol. It is a conjugate acid of a 7,4'-O-dimethylkaempferol 3-olate.

References

[1] Teeratad, et al. Inhibition of nitric oxide production by compounds from Boesenbergia longiflora using lipopolysaccharide-stimulated RAW264.7 macrophage cells.[J]. Songklanakarin Journal of Science & Technology, 2013.
[2] To D-C, et al. PTP1B Inhibitory Flavonoids From Orthosiphon stamineus Benth. and Their Growth Inhibition on Human Breast Cancer Cells. Natural Product Communications. 2020,15(1).

3,5-DIHYDROXY-7-METHOXY-2-(4-METHOXY-PHENYL)-CHROMEN-4-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

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3,5-DIHYDROXY-7-METHOXY-2-(4-METHOXY-PHENYL)-CHROMEN-4-ONE Suppliers

China 58 United Kingdom 7 United States 10 Global 75

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15486-33-6, 3,5-DIHYDROXY-7-METHOXY-2-(4-METHOXY-PHENYL)-CHROMEN-4-ONERelated Search:

Kaempferol KAEMPFEROL-7-O-GLUCOSIDE Kaempferol 3-neohesperidoside 7-[[2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-3,5-dihydroxy-2-(4-hydroxyphenyl)-4H-benzopyran-4-one kaempferol-3-O-galactoside KaeMpferol-4'-O-β-D-glucopyranoside KaeMpferol 7-O-rhaMnoside KAEMPFEROL-3-GLUCURONIDE Kaempferol-3-O-(2,6-di-O-trans-p-coumaroyl)-beta-D-glucopyranoside Kaempferol 3-(6-O-glucopyranosylglucoside) Kaempferol 3-sophoroside-7-glucoside KAEMPFEROL-3-O-RUTINOSIDE kaempferol 3-O-sophoroside kaempferol-3-O-glucosyl(1-2)rhamnoside KaeMpferol 3-sophoroside-7-rhaMnoside Kaempferol-3-O-(2"-O-β-D- glucopyl)-β-D–rutinoside KAEMPFEROL 3-A-L-ARABINOPYRANOSIDE 4H-1-Benzopyran-4-one, 3-[[6-deoxy-2-O-[6-O-[(2Z)-3-(4-hydroxyphenyl)-1-oxo-2-propen-1-yl]-β-D-glucopyranosyl]-α-L-mannopyranosyl]oxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-

KAEMPFEROL-7,4'-DIMETHYL ETHER

3,5-DIHYDROXY-7,4'-DIMETHOXYFLAVONE

3,5-DIHYDROXY-7-METHOXY-2-(4-METHOXY-PHENYL)-CHROMEN-4-ONE

3,5-dihydroxy-7-methoxy-2-(4-methoxyphenyl)-4-benzopyrone

3,5-Dihydroxy-7-methoxy-2-(4-methoxy-phenyl)-

2-(4-Methoxyphenyl)-3,5-dihydroxy-7-methoxy-4H-1-benzopyran-4-one

4'-O,7-O-Dimethylkaempferol

Kaempferol 4',7-dimethyl ether

Einecs 239-513-1

3,5-Dihydroxy-7-Methoxy-2-(4-Methoxyphenyl)-4H-chroMen-4-one

3,5-DIHYDROXY-4',7-DIMETHOXYFLAV

7-dimethoxyflavone

4H-1-Benzopyran-4-one, 3,5-dihydroxy-7-methoxy-2-(4-methoxyphenyl)-

5-Dihydroxy-4'

3,5-Dihydroxy-4',7-dimethoxyflavone

Kaempferol 7,4'-dimethyl ether

7-O-Dimethylkaempferol

Kaempferol-4',7-dimethylether

Kaempferol-7,4''-dimethyl ether

15486-33-6

Flavanols