BI8622

Product Name: BI8622
CAS No.: 1875036-74-0
Chemical Name: BI8622
Synonyms: BI8622;BI8622 (BI-8622;4-Pyrimidinecarboxamide, N-[4-(aminomethyl)phenyl]-6-(4-cyano-4-phenyl-1-piperidinyl)-5-methyl-
CBNumber: CB84667638
Molecular Formula: C25H26N6O
Formula Weight: 426.51
MOL File: 1875036-74-0.mol

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BI8622 Property

Boiling point:: 632.6±55.0 °C(Predicted)
Density: 1.29±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO : 125 mg/mL (293.08 mM; Need ultrasonic)
form: Solid
pka: 11.59±0.70(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0079660
Product name: BI8622
Purity: 99.35%
Packaging: 5mg
Price: $350
Updated: 2021/12/16

ChemScene

Product number: CS-0079660
Product name: BI8622
Purity: 99.35%
Packaging: 10mg
Price: $550
Updated: 2021/12/16

ChemScene

Product number: CS-0079660
Product name: BI8622
Purity: 99.35%
Packaging: 50mg
Price: $1650
Updated: 2021/12/16

ChemScene

Product number: CS-0079660
Product name: BI8622
Purity: 99.35%
Packaging: 100mg
Price: $2250
Updated: 2021/12/16

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BI8622 Chemical Properties,Usage,Production

Biological Activity

BI8622 is a selective HUWE1 (HECTH9; MULE; ARF-BP1) inhibitor (IC50 = 3.2 μM by HUWE1 HECT-domain auto-ubiquitination assay; IC50 >50 μM against other HECT-domain Ub ligases tested). BI8622 inhibits the degradation of HUWE1 target proteiins, including MCL1 (IC50 = 6.8 μM; UV irradiated HeLa MCL1 transfectants), MIZ1 (10 μM; Ls174T), and TopBP1. BI8622 suppresses Ls174T colony formation (IC50 = 8.4 μM in 5 days) and the growth of three colon carcinoma cell lines (20 μM for 5 days; HCT116, HT29, SW480).

BI8622 Preparation Products And Raw materials

Raw materials

Preparation Products

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BI8622 Suppliers

China 10 United States 5 Global 15

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32161
Advantage: 58

TargetMol Chemicals Inc.

Tel: +8613564774135
Email: zijue.cai@tsbiochem.com
Country: United States
ProdList: 19881
Advantage: 58

TargetMol Chemicals Inc.

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Email: support@targetmol.com
Country: United States
ProdList: 38631
Advantage: 58

Aladdin Scientific

Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 52924
Advantage: 58

MedChemExpress

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Email: sales@medchemexpress.com
Country: United States
ProdList: 6398
Advantage: 58

1875036-74-0, BI8622Related Search:

BI8622

BI8622 (BI-8622

4-Pyrimidinecarboxamide, N-[4-(aminomethyl)phenyl]-6-(4-cyano-4-phenyl-1-piperidinyl)-5-methyl-

1875036-74-0