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METHYL 2-BROMOMETHYL-6-CHLORO-BENZOATE

Product Name
METHYL 2-BROMOMETHYL-6-CHLORO-BENZOATE
CAS No.
482578-63-2
Chemical Name
METHYL 2-BROMOMETHYL-6-CHLORO-BENZOATE
Synonyms
METHYL 2-BROMOMETHYL-6-CHLORO-BENZOATE;Benzoic acid, 2-(bromomethyl)-6-chloro-, methyl ester;METHYL 2-BROMOMETHYL-6-CHLORO-BENZOATE Benzoic acid, 2-(bromomethyl)-6-chloro-, methyl ester
CBNumber
CB8472209
Molecular Formula
C9H8BrClO2
Formula Weight
263.52
MOL File
482578-63-2.mol
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

AK Scientific
Product number
6604AB
Product name
Methyl2-(bromomethyl)-6-chlorobenzoate
Packaging
100mg
Price
$147
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
36043
Product name
Methyl2-(bromomethyl)-6-chlorobenzoate
Purity
95+%
Packaging
1g
Price
$780
Updated
2021/12/16
Ambeed
Product number
A350275
Product name
Methyl2-(bromomethyl)-6-chlorobenzoate
Purity
95+%
Packaging
100mg
Price
$43
Updated
2021/12/16
Ambeed
Product number
A350275
Product name
Methyl2-(bromomethyl)-6-chlorobenzoate
Purity
95+%
Packaging
250mg
Price
$84
Updated
2021/12/16
Ambeed
Product number
A350275
Product name
Methyl2-(bromomethyl)-6-chlorobenzoate
Purity
95+%
Packaging
1g
Price
$210
Updated
2021/12/16
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METHYL 2-BROMOMETHYL-6-CHLORO-BENZOATE Chemical Properties,Usage,Production

Synthesis

99585-14-5

482578-63-2

Methyl 2-chloro-6-methylbenzoate (1 g, 5.4 mmol) was used as starting material and dissolved in carbon tetrachloride (50 mL). Subsequently, N-bromosuccinimide (1 g, 5.9 mmol) and benzoyl peroxide (0.131 g, 0.5 mmol) were sequentially added to this solution. The reaction mixture was stirred continuously at 80 °C for 10 hours. After completion of the reaction, the mixture was filtered through diatomaceous earth to remove insoluble impurities. The filtrate was concentrated under reduced pressure to afford the target product methyl 2-(bromomethyl)-6-chlorobenzoate (1.2 g). The structure of the product was confirmed by LC-MS with a calculated exact mass of 261.94 and a measured value of m/z 263.0 [M + H]+.

References

[1] Patent: WO2006/77414, 2006, A1. Location in patent: Page/Page column 150
[2] Patent: US2010/249095, 2010, A1. Location in patent: Page/Page column 91
[3] Patent: US2007/32475, 2007, A1. Location in patent: Page/Page column 32
[4] Patent: EP1408033, 2004, A1. Location in patent: Page 115
[5] Bioorganic and Medicinal Chemistry Letters, 2013, vol. 23, # 1, p. 360 - 365

METHYL 2-BROMOMETHYL-6-CHLORO-BENZOATE Preparation Products And Raw materials

Raw materials

Preparation Products

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METHYL 2-BROMOMETHYL-6-CHLORO-BENZOATE Suppliers

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482578-63-2, METHYL 2-BROMOMETHYL-6-CHLORO-BENZOATERelated Search:


  • METHYL 2-BROMOMETHYL-6-CHLORO-BENZOATE Benzoic acid, 2-(bromomethyl)-6-chloro-, methyl ester
  • METHYL 2-BROMOMETHYL-6-CHLORO-BENZOATE
  • Benzoic acid, 2-(bromomethyl)-6-chloro-, methyl ester
  • 482578-63-2