N-Methylphthalimide

Product Name: N-Methylphthalimide
CAS No.: 550-44-7
Chemical Name: N-Methylphthalimide
Synonyms: 2-Methylisoindoline-1,3-dione;T56 BVNVJ C1;METHYL PHTHALIMIDE;n-methyl-phthalimid;N-METHYLPHTHALIMIDE;PHTHALIMIDE-N-METHYL;N-Methylphthalimide>Methylisoindolinedione;Rivaroxaban Impurity 20;2-Methyl-1H-isoindole-1
CBNumber: CB8473039
Molecular Formula: C9H7NO2
Formula Weight: 161.16
MOL File: 550-44-7.mol

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N-Methylphthalimide Property

Melting point:: 129-132 °C (lit.)
Boiling point:: 286.05°C
Density: 1.2443 (rough estimate)
refractive index: 1.4500 (estimate)
storage temp.: Sealed in dry,Room Temperature
solubility: DMSO (Slightly), Methanol (Slightly)
pka: -2.09±0.20(Predicted)
form: Solid
color: White to Off-White
BRN: 124428
InChI: InChI=1S/C9H7NO2/c1-10-8(11)6-4-2-3-5-7(6)9(10)12/h2-5H,1H3
InChIKey: ZXLYYQUMYFHCLQ-UHFFFAOYSA-N
SMILES: C1(=O)C2=C(C=CC=C2)C(=O)N1C
CAS DataBase Reference: 550-44-7(CAS DataBase Reference)
NIST Chemistry Reference: 1H-Isoindole-1,3(2H)-dione, 2-methyl-(550-44-7)
EPA Substance Registry System: 1H-Isoindole-1,3(2H)-dione, 2-methyl- (550-44-7)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 1
RTECS: TI5602700
TSCA: Yes
HazardClass: IRRITANT
HS Code: 29251900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 407992
Product name: N-Methylphthalimide
Purity: 98%
Packaging: 5g
Price: $40.37
Updated: 2025/07/31

TCI Chemical

Product number: M0299
Product name: N-Methylphthalimide
Purity: >99.0%(GC)
Packaging: 25g
Price: $66
Updated: 2025/07/31

TRC

Product number: M314360
Product name: 2-Methylisoindole-1,3-dione
Packaging: 100g
Price: $155
Updated: 2021/12/16

Frontier Specialty Chemicals

Product number: JK586813
Product name: N-Methylphthalimide
Purity: 98%
Packaging: 5g
Price: $23
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H48-1-71
Product name: N-Methylphthalimide
Packaging: 5G
Price: $44
Updated: 2021/12/16

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N-Methylphthalimide Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

Photoreduction of N-methylphthalimide (NMP) with 2,3-dimethyl-2-butene h and the selective electroreduction of N-methylphthalimide to 3-hydroxy-2-methyl-isoindolin-1-one have been studied.

Synthesis Reference(s)

The Journal of Organic Chemistry, 44, p. 497, 1979 DOI: 10.1021/jo01318a005

General Description

Photoreduction of N-methylphthalimide (NMP) with 2,3-dimethyl-2-butene has been studied. The selective electroreduction of N-methylphthalimide to 3-hydroxy-2-methyl-isoindolin-1-one in ionic liquids and phenol as a proton donor under silent and ultrasonic conditions has been reported. Single electron transfer (SET)-induced photochemical reaction of NMP with silyl enol ether has been investigated. Nitration of NMP is reported to afford “exclusively” 3-nitro-derivative.

Purification Methods

Recrystallise the imide from absolute EtOH or AcOH (m 134o). The IR has max at 1780 and 1380cm -1. [Beilstein 21 H 461, 21 III/IV 5030.]

N-Methylphthalimide Preparation Products And Raw materials

Raw materials

Preparation Products

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N-Methylphthalimide Suppliers

Americas 1 Canada 2 China 282 Europe 5 Germany 4 India 30 Japan 3 Switzerland 2 The Netherlands 1 United Kingdom 9 United States 36 Global 375

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View Lastest Price from N-Methylphthalimide manufacturers

YiZheng HaiFan Chemical CO., LTD.

Product: N-methylphthalimide 550-44-7
Price: US $0.00/kgs/bag
Min. Order: 25kgs/bag
Purity: 99%
Supply Ability: 10 tons
Release date: 2025-11-17

Hebei Zhuanglai Chemical Trading Co Ltd

Product: N-Methylphthalimide 550-44-7
Price: US $45.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20 tons
Release date: 2024-12-24

Nanjing Kaitian Chemical Co., LTD

Product: N-methylphthalimide 550-44-7
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 500 tons
Release date: 2022-12-06

550-44-7, N-MethylphthalimideRelated Search:

3-Nitrophthalimide Bismaleimide N-Hydroxyphthalimide Succinimide Phthalhydrazide 4-Aminophthalimide 4-Nitrophthalimide O-Phthalimide Potassium phthalimide N-MethyltrifluoroMethanesulfonaMide N-Methyl-1,2-benzenediamine dihydrochloride Rivaroxaban Metabolite 8 2-Chlorothiophene Rivaroxaban Diol (Mixture of Diastereomers) Rivaroxaban Metabolite 9 Rivaroxaban iMpurity 9 Rivaroxaban IMpurity F Rivaroxaban iMpurity

2-Methylisoindoline-1,3-dione

2-Methyl-1H-isoindole-1

Rivaroxaban Impurity F ( N-Methyl Phthalimide ) CAS No. 550-44-7

Imp. F:N-Methylphthalimide

Rivaroxaban impurity P1-B

Rivaroxaban N-Methylphthalimide Impurity

Rivaroxaban Impurity F ( N-Methyl Phthalimide )

Rivaroxaban Impurity 20

1H-Isoindole-1,3(2H)-dione,2-methyl-

2-Methyl-1H-isoindol-1,3(2H)-dion

2-methyl-1h-isoindole-3(2h)-dione

2-Methyl-isoindole-1,3-dione

n-methyl-phthalimid

N-METHYLPHTHALIMIDE

PHTHALIMIDE-N-METHYL

2-METHYL-1H-ISOINDOLE-1,3(2H)-DIONE

METHYL PHTHALIMIDE

N-Methylphthalimide,98%

n-methyl-1h-isoindole-1,3-(2h)-dione

Rivaroxaban related mixture 1 (N-methyl collar phthalimide)

N-Methylphthalimide&gt

Rivaroxaban Impurity F/ Rivaroxaban N-Methylphthalimide Impurity

T56 BVNVJ C1

Rivaroxaban Impurity 99 (N-Methyl Phthalimide)

Methylisoindolinedione

<i>N</i>-Methylphthalimide

550-44-7

Carbonyl Compounds

Building Blocks

Cyclic Imides

Organic Building Blocks

N-Substituted Maleimides, Succinimides & Phthalimides

N-Substituted Phthalimides

intermediates

N-Substituted Maleimides, Succinimides & Phthalimides

N-Substituted Phthalimides

Cyclic ImidesDerivatization Reagents

Carbonyl Compounds

Derivatization Reagents HPLC

Organic Building Blocks

UV-VIS

API intermediates