ChemicalBook > CAS DataBase List > N-Hydroxyphthalimide

N-Hydroxyphthalimide

Product Name
N-Hydroxyphthalimide
CAS No.
524-38-9
Chemical Name
N-Hydroxyphthalimide
Synonyms
nhpi;f802;HOPHT;NHPI NOP;PHTHALOXIME;AURORA KA-3774;N-HydroxyphthaL;hydroxyphthalimide;TIMTEC-BB SBB009098;N-HYDROXYPHTHALIMIDE
CBNumber
CB2332640
Molecular Formula
C8H5NO3
Formula Weight
163.13
MOL File
524-38-9.mol
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N-Hydroxyphthalimide Property

Melting point:
233 °C (dec.) (lit.)
Boiling point:
290.19°C (rough estimate)
Density 
1.64 g/cm3
refractive index 
1.5510 (estimate)
storage temp. 
Store at RT.
pka
6.10±0.20(Predicted)
form 
Powder
color 
Yellow
Water Solubility 
Slightly soluble in water.
Merck 
14,4838
BRN 
131208
InChIKey
CFMZSMGAMPBRBE-UHFFFAOYSA-N
CAS DataBase Reference
524-38-9(CAS DataBase Reference)
EPA Substance Registry System
1H-Isoindole-1,3(2H)-dione, 2-hydroxy- (524-38-9)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39
WGK Germany 
3
RTECS 
TI5200000
TSCA 
Yes
HazardClass 
IRRITANT
HS Code 
29251995
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
H53704
Product name
N-Hydroxyphthalimide
Purity
97%
Packaging
100g
Price
$38.7
Updated
2021/03/22
Sigma-Aldrich
Product number
H53704
Product name
N-Hydroxyphthalimide
Purity
97%
Packaging
5g
Price
$17.6
Updated
2021/03/22
TCI Chemical
Product number
H0395
Product name
N-Hydroxyphthalimide
Purity
>99.0%(T)
Packaging
25g
Price
$17
Updated
2021/03/22
TCI Chemical
Product number
H0395
Product name
N-Hydroxyphthalimide
Purity
>99.0%(T)
Packaging
100g
Price
$48
Updated
2021/03/22
Alfa Aesar
Product number
A13862
Product name
N-Hydroxyphthalimide, 98+%
Packaging
500g
Price
$126
Updated
2021/03/22
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N-Hydroxyphthalimide Chemical Properties,Usage,Production

Chemical Properties

N-Hydroxyphthalimide is yellow moist powder

Uses

N-Hydroxyphthalimide,additives in to DCC method of peptide synthesis used to improve yield of optically pure product.

Uses

Catalyst for oxidation reactions.

Synthesis Reference(s)

Tetrahedron Letters, 37, p. 2035, 1996 DOI: 10.1016/0040-4039(96)00211-0

Purification Methods

N -Hydroxyphthalimide [524-38-9] M 163.1, m 230o, ~235o(dec), 237-240o, 7.0. Dissolve the imide in H2O by adding Et3N to form the salt and while hot, acidify, cool and pour into a large volume of H2O. Filter off the solid, wash it with H2O and dry it over P2O5 in a vacuum. [Nefken & Teser J Am Chem Soc 83 1263 1961, Fieser 1 485 1976, Nefkens et al. Recl Trav Chim, Pays-Bas 81 683 1962] The O-acetyl derivative has m 178-180o (from EtOH). [Beilstein 21/11 V 100.]

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N-Hydroxyphthalimide Suppliers

Nanjing Taihehua Electronics Co., Ltd
Tel
Email
943629434@qq.com
Country
China
ProdList
9
Advantage
58
Shanghai He Huan Chemical Co., Ltd.
Tel
021-60345187
Fax
021-60345187
Email
lzz841106@aliyun.com
Country
CHINA
ProdList
9846
Advantage
58
Shanghai QianYan Bio-technology Co., Ltd
Tel
02781293128
Email
orders@biochemsafebuy.com
Country
China
ProdList
9965
Advantage
55
Jiangsu lianrun chemical co. LTD
Tel
0517-85322222-
Email
sales@lianrunchem.com
Country
China
ProdList
8
Advantage
58
Tianjin Zhongxin Chemtech Co., Ltd.
Tel
022-66880623;022-89880623
Fax
86(0)22-66880086
Email
sales@tjzxchem.com;sales@tjzxchem.com
Country
China
ProdList
617
Advantage
60
J & K SCIENTIFIC LTD.
Tel
010-82848833- ;010-82848833-
Fax
86-10-82849933
Email
jkinfo@jkchemical.com;market6@jkchemical.com
Country
China
ProdList
96500
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
21-61259100-
Fax
86-21-61259102
Email
sh@meryer.com
Country
China
ProdList
40264
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15877
Advantage
69
future industrial shanghai co., ltd
Tel
400-0066-400;021-60496031
Fax
021-55660885
Email
sales@jonln.com;sales@jonln.com
Country
China
ProdList
2000
Advantage
65
Alfa Aesar
Tel
400-610-6006; 021-67582000
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30159
Advantage
84
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View Lastest Price from N-Hydroxyphthalimide manufacturers

Hebei Guanlang Biotechnology Co., Ltd.
Product
N-Hydroxyphthalimide 524-38-9
Price
US $10.00/PCS
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2021-07-19
Zhuozhou Wenxi import and Export Co., Ltd
Product
N-Hydroxyphthalimide 524-38-9
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
N-Hydroxyphthalimide 524-38-9
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-08

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