APOLIPOPROTEIN A-I, HUMAN

Product Name
APOLIPOPROTEIN A-I, HUMAN
Chemical Name
APOLIPOPROTEIN A-I, HUMAN
Synonyms
APO A-1;C117399;APO A-I;MGC117399;HUMAN APOA-I;APO-A1, HUMAN;APO A-I, HUMAN;ApoA-1 from rat;APOLIPROTEIN A-I;APOLIPOPROTEIN AI
CBNumber
CB8474566
Formula Weight
0
MOL File
Mol file
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APOLIPOPROTEIN A-I, HUMAN Property

storage temp. 
−20°C
solubility 
H2O: 1 mg/mL, clear, colorless
form 
solution (clear)
color 
colorless
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Safety

Hazard Codes 
B
Safety Statements 
23-24/25
WGK Germany 
3
F 
10-21
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SAB2502171
Product name
Anti-APOA1 antibody produced in goat
Purity
affinity isolated antibody, buffered aqueous solution
Packaging
100μG
Price
$568
Updated
2024/03/01
Sigma-Aldrich
Product number
178452
Product name
Apolipoprotein A-I, Human Plasma, High-Density Lipoprotein
Purity
Native apolipoprotein A-I from human plasma. Functions as a cofactor for lecithin-cholesterol acyltransferase. A component of high density lipoprotein.
Packaging
500μg
Price
$247
Updated
2024/03/01
Sigma-Aldrich
Product number
SRP4693
Product name
Apolipoprotein A−I human
Purity
recombinant, expressed in E. coli, ≥97% (SDS-PAGE), ≥97% (HPLC)
Packaging
100μG
Price
$345
Updated
2023/06/20
Usbiological
Product number
A2299-10F
Product name
Apolipoprotein A-I, Human
Packaging
500ug
Price
$375
Updated
2021/12/16
Usbiological
Product number
139298
Product name
Apolipoprotein AI
Packaging
200ul
Price
$438
Updated
2021/12/16
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APOLIPOPROTEIN A-I, HUMAN Chemical Properties,Usage,Production

Uses

Apolipoprotein A-I human has been used in the cholesterol efflux assay.

General Description

ApoA-I, which is found exclusively in HDL, has a unique ability to capture and solubilize free cholesterol. This apoA-I ability enables HDL to remove excess peripheral cholesterol and return it to the liver for recycling and excretion. This process, called reverse cholesterol transport, is though to inhibit atherogenesis. For this reason HDL is also known as the "good cholesterol." The therapeutic potential of apoA-I has been recently assessed in patients with acute coronary syndromes, using a recombinant form of a naturally occurring variant of apoA-I (called apoA-I Milano). The availability of recombinant normal apoA-I should facilitate further investigation into the potential usefulness of apoA-I in preventing atherosclerotic vascular diseases.

Biochem/physiol Actions

ApoA-I (apolipoprotein A-I), which is found exclusively in HDL (high-density lipoprotein), has a unique ability to capture and solubilize free cholesterol. This apoA-I ability enables HDL to remove excess peripheral cholesterol and return it to the liver for recycling and excretion. This process, called reverse cholesterol transport, is thought to inhibit atherogenesis. For this reason HDL is also known as the "good cholesterol." The therapeutic potential of apoA-I has been recently assessed in patients with acute coronary syndromes, using a recombinant form of a naturally occurring variant of apoA-I (called apoA-I Milano). The availability of recombinant normal apoA-I should facilitate further investigation into the potential usefulness of apoA-I in preventing atherosclerotic vascular diseases. Changes in the level of serum apoA-I may serve as a prognostic marker for non-metastatic nasopharyngeal carcinoma. Low levels of apoA-I in the plasma is linked to hyperhomocysteinemia.

APOLIPOPROTEIN A-I, HUMAN Preparation Products And Raw materials

Raw materials

Preparation Products

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APOLIPOPROTEIN A-I, HUMAN Suppliers

China 31 Germany 2 Japan 1 Switzerland 1 United Kingdom 1 United States 10 Global 46
United States Biological
Tel
--
Fax
--
Email
sales@advtechind.com
Country
United States
ProdList
6075
Advantage
58
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
EMD Biosciences, Inc.
Tel
--
Fax
--
Email
technical@calbiochem.com
Country
United States
ProdList
6529
Advantage
66
MP Biomedicals, Inc.
Tel
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Fax
--
Country
United States
ProdList
6561
Advantage
81
BIODESIGN International/OEM Concepts
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Fax
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Email
info@biodesign.com
Country
United States
ProdList
2376
Advantage
50
Scripps Laboratories, Inc.
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--
Email
contact@scrippslabs.com
Country
United States
ProdList
156
Advantage
72
PeproTech Inc.
Tel
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Fax
--
Email
info@peprotech.com
Country
United States
ProdList
644
Advantage
75
OEM Concepts
Tel
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Fax
--
Country
United States
ProdList
540
Advantage
50
Chemicon Internatinal, Inc.
Tel
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Email
custserv@chemicon.com
Country
United States
ProdList
4175
Advantage
65
Cortex Biochem, Inc.
Tel
--
Fax
--
Email
info@cortex-biochem.com
Country
United States
ProdList
1557
Advantage
77

APOLIPOPROTEIN A-I, HUMANRelated Search:


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