18β-Glycyrrhetinic Acid

ChemicalBook > CAS DataBase List > 18β-Glycyrrhetinic Acid

18β-Glycyrrhetinic Acid

Product Name: 18β-Glycyrrhetinic Acid
CAS No.: 471-53-4
Chemical Name: 18β-Glycyrrhetinic Acid
Synonyms: GLYCYRRHETINIC ACID;ENOXOLONE;GLYCYRRHETIC ACID;Glycyrrhetinic;Glycyrrhetinate;biosone;URALENIC ACID;18β-Glycyrrhetic acid;18B-GLYCYRRHETINIC ACID;(2S,4aS,6aR,6aS,6bR,8aR,10S,12aS,14bR)-10-hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-3,4,5,6,6a,7,8,8a,10,11,12,14b-dodecahydro-1H-picene-2-carboxylic acid
CBNumber: CB8474793
Molecular Formula: C30H46O4
Formula Weight: 470.69
MOL File: 471-53-4.mol

Less

18β-Glycyrrhetinic Acid Property

Melting point:: 292-295 °C(lit.)
alpha: 165 º (c=1, CHCl3,on dry ba)
Boiling point:: 492.11°C (rough estimate)
Density: 0.9967 (rough estimate)
vapor pressure: 10-220Pa at 20-50℃
refractive index: 162 ° (C=1, MeOH)
storage temp.: 2-8°C
solubility: Practically insoluble in water, soluble in ethanol, sparingly soluble in methylene chloride.
pka: pKa 5.56±0.1 (Uncertain)
form: Crystalline Powder
color: White to off-white
optical activity: [α]22/D +170.0°, c = 1 in chloroform
Water Solubility: SOLUBLE IN ACETIC ACID
Merck: 14,3590
BRN: 2229654
LogP: 4.5 at 20℃
CAS DataBase Reference: 471-53-4(CAS DataBase Reference)
EPA Substance Registry System: Enoxolone (471-53-4)

Less

Safety

Hazard Codes: Xn
Risk Statements: 22-36
Safety Statements: 22-24/25
WGK Germany: 3
RTECS: RK0180000
HS Code: 29189900
Toxicity: mouse,LD50,intraperitoneal,308mg/kg (308mg/kg),Drugs in Japan Vol. -, Pg. 319, 1990.

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P330Rinse mouth.

P501Dispose of contents/container to..…

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: G10105
Product name: 18β-Glycyrrhetinic acid
Purity: 97%
Packaging: 10g
Price: $117
Updated: 2024/03/01

Sigma-Aldrich

Product number: G10105
Product name: 18β-Glycyrrhetinic acid
Purity: 97%
Packaging: 25g
Price: $227
Updated: 2024/03/01

TCI Chemical

Product number: G0149
Product name: Glycyrrhetic Acid
Purity: >97.0%(T)
Packaging: 1g
Price: $27
Updated: 2024/03/01

TCI Chemical

Product number: G0149
Product name: Glycyrrhetic Acid
Purity: >97.0%(T)
Packaging: 25g
Price: $192
Updated: 2024/03/01

Cayman Chemical

Product number: 11845
Product name: β-Glycyrrhetinic Acid
Purity: ≥98%
Packaging: 1g
Price: $32
Updated: 2024/03/01

Less

18β-Glycyrrhetinic Acid Chemical Properties,Usage,Production

Description

Extracting from liquorice (Glycyrrhiza uralensis Fisch, Gan Cao), glycyrrhetic acid also can be detected in other plants, such as Abrus cantoniensis Hance and Herba Abri fruticulosi. As one of traditional Chinese medicines, liquorice has been applied clinically for a long period. Due to its extensive usage, it plays an extremely important role in traditional Chinese medicine formula mainly as “guide” drug. As is recorded in Shen Nong’s Herbal Classic and later in pharmaceutical monographs, liquorice is able to strengthen bones and muscles and enhance metabolism and detoxification. Also, abnormal symptoms of the body and wound can be improved. Glycyrrhetic acid, the most important and potent ingredient of liquorice, has been recorded in Pharmacopoeia of the People’s Republic of China.

Description

18β-Glycyrrhetinic acid is a major metabolite of glycyrrhizin , one of the main constituents of licorice. Both 18β-glycyrrhetinic acid and glycyrrhizin have been shown to exhibit anti-ulcerative, anti-inflammatory, and immunomodulatory properties. 18β-Glycyrrhetinic acid is an inhibitor of the complement pathway (IC₅₀ = 35 μM). At 100 mg/kg/day, 18β-glycyrrhetinic acid is protective against diabetes complications by reducing lipid peroxidation and increasing antioxidant activity in diabetic rats. 18β-Glycyrrhetinic acid inhibits mammalian DNA polymerases α, γ, κ, and λ with IC₅₀ values of 16.1, 19.3, 15.8, and 13.7 μM, respectively. At 100-200 μM, 18β-glycyrrhetinic acid suppresses LPS-induced TNF-α production and NF-κB activation in mouse macrophages.

Chemical Properties

white or greyish-white crystalline powder

Physical properties

Solubility: insoluble in water; it exists in crystal with methanol and chloroform. Melting point: the compound melts at 292–295?°C. Specific optical rotation: under the condition of 20?°C, 589.3?nm, and 1?dm, polarized light rotates at 68° when it passes through the chloroform with a concentration of 64? mol/L.? Both 18α-glycyrrhetic acid and 18β-glycyrrhetic acid are chiral isomers of glycyrrhetic acid.

History

Glycyrrhetic acid originates from hydrolysis of glycyrrhizin, which has a therapeutic effect on disease. Dating back to the 1930s, the chemical structure of glycyrrhetic acid was demonstrated . Subsequently, the discovery of antiulcer activity promotes following research . The ramification of glycyrrhetic acid, carbenoxolone sodium, has a therapeutic effect on ulcer. In 2010, followed by the approval of raw materials, batches of tablets and capsules were approved in 2009, respectively. In foreign countries, 18β-glycyrrhetic acid was studied for anti-inflammatory effect on arthritis, rheumatoid disease, and periodontitis in BioNetWorks. The company applied for the patent of 18β-glycyrrhetic acid in 1999. Also, after joining the leading worldwide market in 2006, phase III clinical trials would be carried out in 2007. However, the progress was hindered in 2008. To detecting more indications, its carbenoxolone sodium was studied by other three companies: after conducting phase III clinical trials in the UK, the project of RB intending to improve nonspecific inflammatory bowel disease was given up in 1992. York Pharma expected to make progress in psoriasis with gel or cream; however, the project has been in a standstill after phase II clinical trials was conducted from 2005 to 2009. Canada pharmaceutical company, Oxalys Pharmaceuticals, research it for treating Huntington’s disease, and it was included in the orphan drug list by the USA in 2014. Till now, phase I clinical trials are still continuing.

Uses

The product may be used as a starting material to prepare 18β-glycyrrhetinic acid derivatives, which show anti-inflammatory and antioxidant properties.

Uses

An anti-inflammatory (topical).

Uses

antitussive, antiinflammatory, antibacterial

Uses

The aglycone of the triterpenoid Glyccyrrhizic acid.

Uses

glycyrrhetinic acid is anti-irritant, anti-allergenic, anti-inflammatory, skin-lightening, and smoothing properties are attributed to this ingredient, which is also a carrier. It is the organic compound derived from glycyrrhizic acid or shredded licorice roots.

Definition

ChEBI: A pentacyclic triterpenoid that is olean-12-ene substituted by a hydroxy group at position 3, an oxo group at position 11 and a carboxy group at position 30.

Indications

Treatment of Addison’s disease, deoxycorticosterone

General Description

18β-Glycyrrhetinic acid is a pentacyclic triterpenoid found in the Glycyrrhiza glabra L.(liquorice) roots. It is the key metabolite of glycyrrhizin and glycyrrhizic acid.

Pharmacology

Thirty percent of glycyrrhetinic acid can be effectively used by the body; both 18α-glycyrrhetic acid and 18β-glycyrrhetic acid reduce by half in 2.24 h and 11.5 h separately. CYP3A promotes metabolism with hydroxyl added to 22α and 24α .There are lots of pharmacological activities : it plays an anti-inflammatory role by inhibiting the activity of phospholipase A2 and lipoxygenase to reduce mediators of inflammation; the compound promotes antiulcer activity through the production of more PGE2 and secretion of gastric mucus; it also provokes proliferation of gastric cell to protect the mucosa from ulceration. The complex which consists of glycyrrhetinic acid and carotenoid plays antioxidation by scavenging free radical. Glycyrrhetinic acid inhibits the replication of viral DNA to achieve an antiviral effect at the concentration of 4×10?5 mol/L; it also inhibits proliferation of tumor cell and promotes apoptosis and differentiation. The decreasing ability of invasion exerts an antitumor effect. Glycyrrhetinic acid is considered to have extensive antiarrhythmic effects through inhibition of L-type calcium channel. In addition, glycyrrhetinic acid functions as an anticholinesterase (1.7×10?5 mol/L), anticoagulant, and antitetanus toxin; it also improves inner ear hearing (100 mg/kg, intramuscular injection) and improves absorption of insulin.

Anticancer Research

Glycyrrhetinic acid in combinationwith etoposide inhibits thetopoisomerase 2α and inducesapoptosis
Cai et al.(2017)

Anticancer Research

It was reported that GA at noncytotoxic concentrationshowed synergistic effect in combination with anticancer drug, etoposide (VP-16).Specifically, GA enhanced cytotoxicity through regulating topoisomerase II-αtargeted by etoposide. Also, GA sensitized the cells to etoposide through elevatingtopoisomerase II-α with a 2.4-fold rate at 12 h time point. From 12 to 48 h, GAhalved the expression of topoisomerase II-α and stimulated apoptosis, whichexhibited its antineoplastic effect. They reported that GA was more potentiallyeliminating the TNBC cells when compared with Glycyrrhizin Acid (Cai et al. 2017).

Clinical Use

Glycyrrhetic acid has not been applied in clinical treatment till now. Meanwhile, the ramification has come into the market for the property of antiulcer. However, with large doses and long-term usage, the drug gives rise to hypertension, sodium retention, and hypokalemia. When renin-angiotensin-aldosterone system fails to function properly, liquorice-induced pseudoaldosteronism threatens human health .

18β-Glycyrrhetinic Acid Preparation Products And Raw materials

Raw materials

Glycyrrhizic acid SIS Ethanol Triammonium glycyrrhizinate Sucrose DGL weak

Preparation Products

Less

18β-Glycyrrhetinic Acid Suppliers

Americas 1 Belgium 2 Canada 3 China 440 Czech Republic 1 Europe 3 France 8 Germany 5 India 19 Italy 1 Japan 11 Poland 2 Slovakia 1 South Korea 3 Switzerland 4 The Netherlands 1 Turkey 1 United Kingdom 18 United States 58 Global 582

Youyu County Andyiyuan Biotechnology Co., LTD

Tel: 03498026555; 15110806857
Email: 747157139@qq.com
Country: China
ProdList: 22
Advantage: 58

Shanghai Winherb Medical Technology Co., Ltd.

Tel: 400-1865138 13341702378
Fax: QQ：190129269
Email: 190129269@qq.com
Country: China
ProdList: 1009
Advantage: 58

CHENGDU JINMAIRUI BIO-TECHNOLOGY CO.LTD

Tel: 028-83133020 18280298385
Email: 1223808415@qq.com
Country: China
ProdList: 497
Advantage: 58

Shanghai Boyle Chemical Co., Ltd.

Tel: 021-50182298 021-50180596
Fax: +86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2210
Advantage: 55

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006608290; 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40241
Advantage: 62

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15848
Advantage: 69

Chembest Research Laboratories Limited

Tel: 021-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6011
Advantage: 61

TAIYUAN RHF CO.,LTD.

Tel: +86 351 7031519
Fax: +86 351 7031519
Email: sales@RHFChem.com
Country: China
ProdList: 2341
Advantage: 56

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24539
Advantage: 81

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44751
Advantage: 61

Shanghai Longsheng chemical Co.,Ltd.

Tel: 021-58099652-8005 13585536065
Fax: 021-58099609
Email: bin.wu@shlschem.com
Country: China
ProdList: 9816
Advantage: 59

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696;
Email: info@hanhongsci.com
Country: China
ProdList: 42982
Advantage: 64

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32344
Advantage: 50

Shandong Xiya Chemical Co., Ltd

Tel: 13355009207 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18739
Advantage: 57

BEST-REAGENT

Tel: 400-1166-196 18981987031
Fax: 028-84555506 800101999
Email: cdhxsj@163.com
Country: China
ProdList: 11726
Advantage: 57

China Langchem Inc.

Tel: 0086-21-58956006
Fax: 0086-21-58956100
Country: China
ProdList: 7815
Advantage: 57

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400 638 7771
Email: sales@heowns.com
Country: China
ProdList: 14443
Advantage: 57

Sinopharm Chemical Reagent Co,Ltd.

Tel: 86-21-63210123
Fax: 86-21-63290778 86-21-63218885
Email: sj_scrc@sinopharm.com
Country: China
ProdList: 9823
Advantage: 79

Hunan Hui Bai Shi Biotechnology Co., Ltd.

Tel: 0731-85526065 13308475853
Email: ivy@hnhbsj.com
Country: China
ProdList: 4550
Advantage: 62

Aktin Chemicals, Inc.

Tel: 86-28-85159085
Fax: 86-28-85152372
Email: info@aktinchem.com
Country: China
ProdList: 297
Advantage: 62

Spectrum Chemical Manufacturing Corp.

Tel: 021-021-021-67601398-809-809-809 15221380277
Fax: 021-57711696
Email: marketing_china@spectrumchemical.com
Country: China
ProdList: 9664
Advantage: 60

Dalian Meilun Biotech Co., Ltd.

Tel: 0411-62910999 13889544652
Email: sales@meilune.com
Country: China
ProdList: 4647
Advantage: 58

BioBioPha Co., Ltd.

Tel: 0871-65217109 13211707573;
Fax: 0871-65215563
Email: y.liu@mail.biobiopha.com
Country: China
ProdList: 5654
Advantage: 65

ShangHai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847 13636370518
Fax: 021-55068248
Email: shyysw007@163.com
Country: China
ProdList: 4941
Advantage: 60

Chengdu Ai Keda Chemical Technology Co., Ltd.

Tel: 4008-755-333 18080918076
Fax: 028-86757656
Email: 800078821@qq.com
Country: China
ProdList: 9725
Advantage: 55

T&W GROUP

Tel: 021-61551611 13296011611
Fax: ＋86 21-50676805
Email: contact@trustwe.com
Country: China
ProdList: 9900
Advantage: 58

Chengdu Climax Biotech Co., Ltd.

Tel: 028-83311324 1278112614
Fax: 028-83311324
Email: climaxbiotech@gmail.com
Country: China
ProdList: 925
Advantage: 58

S.Z. PhyStandard Bio-Tech. Co., Ltd.

Tel: 0755-4000505016 13380397412
Fax: 0755 28094224
Email: 3001272453@qq.com
Country: China
ProdList: 4978
Advantage: 50

Shanghai civi chemical technology co.,Ltd

Tel: 86-21-34053660
Fax: 86-21-34053661
Email: sale@labgogo.com
Country: China
ProdList: 9872
Advantage: 52

Thermo Fisher Scientific

Tel: 800-810-5118
Fax: +86-10-84193589
Email: cnchemical@thermofisher.com
Country: China
ProdList: 17779
Advantage: 75

Beijing HuaMeiHuLiBiological Chemical

Tel: 010-56205725
Fax: 010-65763397
Email: waley188@sohu.com
Country: China
ProdList: 12338
Advantage: 58

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 22519
Advantage: 55

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-6206333 18521732826;
Fax: 021-50323701
Email: market@aladdin-e.com
Country: China
ProdList: 25015
Advantage: 65

The future of Shanghai Industrial Co., Ltd.

Tel: 021-61552785
Fax: 021-55660885
Email: sales@shshiji.com
Country: China
ProdList: 9552
Advantage: 55

Shanghai Tauto Biotech Co., Ltd.

Tel: 021-51320588
Fax: 0086-21-51320502
Email: tauto@tautobiotech.com
Country: China
ProdList: 3989
Advantage: 66

Guangzhou Isun Pharmaceutical Co., Ltd

Tel: 020-39119399 18927568969
Fax: 020-39119999
Email: isunpharm@qq.com
Country: China
ProdList: 4428
Advantage: 55

Nanjing Sunlida Biological Technology Co., Ltd.

Tel: 025-57798810
Fax: 025-57019371
Email: sales@sunlidabio.com
Country: China
ProdList: 3750
Advantage: 55

TargetMol Chemicals Inc.

Tel: 021-33632979 15002134094
Fax: 021-33632979
Email: marketing@targetmol.com
Country: China
ProdList: 7934
Advantage: 58

Chengdu Herbpurify Co.Ltd.

Tel: 18302802153 18981717076
Fax: 086-28-85377358
Email: 2355253619@qq.com
Country: China
ProdList: 1104
Advantage: 58

Shanghai BeiZhuo Biotech Co., Ltd.

Tel: 021-61119791,13386096464
Fax: 021-50190009
Email: bzswkf@foxmail.com
Country: China
ProdList: 3924
Advantage: 50

Hubei XinyuanShun Chemical Co., Ltd.

Tel: 13971561712, 13995564702, 027-50664929
Fax: 027-50664927
Email: hbeixys2001@163.com
Country: China
ProdList: 3123
Advantage: 55

Shanghai JONLN Reagent Co., Ltd.

Tel: 400-0066400 13621662912
Fax: 021-55660885
Email: 422131432@qq.com
Country: China
ProdList: 9986
Advantage: 55

Shanghai Worldyang Chemical Co.,Ltd.

Tel: 021-021-56795766
Fax: +86-21-56795266
Email: sales@worldyachem.com
Country: China
ProdList: 9353
Advantage: 58

ChemStrong Scientific Co.,Ltd

Tel: 0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 17982
Advantage: 56

Sichuan Wei Keqi Biological Technology Co., Ltd.

Tel: 028-81700200 18116577057
Fax: 028-81705658
Email: 3003855609@qq.com
Country: China
ProdList: 7892
Advantage: 56

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15185
Advantage: 58

Shaanxi Huike Botanical Development Co., Ltd

Tel: +86-29-62663046
Fax: +86-29-82606529
Email: market@huikes.com
Country: China
ProdList: 61
Advantage: 62

Hunan HuaTeng Pharmaceutical Co., Ltd.,

Tel: 400-8592883 15367835770
Fax: 0731-82251112
Email: viola@huatengsci.com
Country: China
ProdList: 5877
Advantage: 58

Shaanxi Pioneer Biotech Co., Ltd.

Tel: 13720616393；029-84385017-8003 13720616393
Fax: 029-84385017
Email: sales@pioneerbiotech.com
Country: China
ProdList: 1065
Advantage: 56

Less

View Lastest Price from 18β-Glycyrrhetinic Acid manufacturers

Shaanxi Haibo Biotechnology Co., Ltd

Product: Aloe vera freeze-dried powder
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10000kg/Month
Release date: 2023-09-11

Henan Tengmao Chemical Technology Co. LTD

Product: 18β-Glycyrrhetinic Acid 471-53-4
Price: US $110.00-90.00/kilogram
Min. Order: 1kilogram
Purity: 99%
Supply Ability: 10 tons/per week
Release date: 2024-03-13

Hebei Yanxi Chemical Co., Ltd.

Product: Enoxolone /Glycyrrhetinic Acid 471-53-4
Price: US $360.00/KG
Min. Order: 10KG
Purity: 98%
Supply Ability: 10tons/month
Release date: 2020-07-15

471-53-4, 18β-Glycyrrhetinic AcidRelated Search:

Glycyrrhizic acid Citric acid CHLOROPHOSPHONAZO III Folic acid Ethyl 2-(Chlorosulfonyl)acetate Hyaluronic acid Diammonium glycyrrhizinate DGL Paeoniflorin Quercetin dihydrate Matrine GLYCYRRHETIC ACID 3-O-GLUCURONIDE Ascoric Acid Stearyl glycyrrhetinate Dipotassium glycyrrhizinate Ammonium Glycyrrhizinate Monopotassium glycyrrhizate cinoxolone

Enoxolone, 3β-Hydroxy-11-oxo-18β,20β-olean-12-en-29-oic acid

Aloe Vera, Freeze Dried Powder

18-β-Glycyrrhetinic acid, 98+%

18-beta-glycyrrheticacid

Olean-12-en-29-oic acid, 3-hydroxy-11-oxo-, (3b,20b)-

(20S)-3β-Hydroxy-11-oxo-5α-olean-12-en-29-oic acid

GLYCYRRHETINIC ACID, 18B-(P)

Glycyrrhetinic acid ,98%

18β-Glycyrrhetinic acid,3β-Hydroxy-11-oxo-18β,20β-olean-12-en-29-oic acid, Enoxolone

GLYCYRRHETINIC ACID, 18B-(SH)

18 β-Glycyrrhetinic Acid / Enoxolone

Glycyrrhetinic acid (Enoxolone)

Rhetinic acid

18 BETA

18b-Glycyrrhetic acid

18beta-Glycyrrhetinic acid 97%

Enoxolone (18-β-glycyrrhetinic acid)

3β-Hydroxy-11-oxoolean-12-en-30-olic acid

Glycyrrhetinate

19β-Glycyrrhetinic acid

20β-Glycyrrhetinic acid

18 β-Glycyrrhetintic Acid

(2S,4aS,6aR,6aS,6bR,8aR,10S,12aS,14bR)-10-hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-3,4,5,6,6a,7,8,8a,10,11,12,14b-dodecahydro-1H-picene-2-carboxylic acid

Glycyrrhetinic acid (beta)

3.beta.-Hydroxy-11-oxo-12-oleanen-30-oicacid

3-beta-hydroxy-11-oxo-olean-12-en-30-oicaci

3-beta-hydroxy-11-oxoolean-12-en-30-oicacid

3-hydroxy-11-oxo-,(3.beta.,20.beta.)-Olean-12-en-29-oicacid

3-hydroxy-11-oxo-,(3beta,20beta)-olean-12-en-29-oicaci

3-Hydroxy-11-oxo-12-oleanen-30-oicacid

URALENIC ACID

3BETA-HYDROXY-11-OXO-18BETA, 20BETA-OLEAN-12-EN-29-OIC ACID

3BETA-HYDROXY-11-OXO-18BETA-OLEAN-12-EN-30-OIC ACID

3b-hydroxy-11-oxo-18b,20b-olean-12-en-29-oic acid

3B-HYDROXY-11-OXO-18B-OLEAN-12-EN-30-OIC ACID

GLYCYRRHETINIC ACID

GLYCYRRHETIC ACID

GLYCYRRHETINIC ACID, 18B-

ENOXOLONE

ENOLOXONE

B-GLYCYRRHETINIC ACID

B-GLYCYRRNETINIC ACID

ENOXACIN GLUCONATE/18BETA-GLYCYRRHETINIC ACID

GLCYRRHETINIC ACID

CARBENOXOLONE(P)

Clycyrrhetinic Acid

18-Beta-Glycyrrheticacid,Uralenicacid

18β-Glycyrrhetic acid

Arthrodont

GM 1658

NSC 35347

Olean-12-en-29-oic acid, 3-hydroxy-11-oxo-, (3β,20β)-

Olean-12-en-30-oic acid, 3β-hydroxy-11-oxo- (8CI)

PO 12

STX 352

Subglycyrrhelinic acid

Uralenic acid (7CI)

GLYCERRHETINICACID