1-BOC-3-METHANESULFONYLOXYPYRROLIDINE

Product Name: 1-BOC-3-METHANESULFONYLOXYPYRROLIDINE
CAS No.: 141699-57-2
Chemical Name: 1-BOC-3-METHANESULFONYLOXYPYRROLIDINE
Synonyms: 138883;(R)-3-(Methylsulphonyloxy)pyrrolidine;1-BOC-3-METHANESULFONYLOXYPYRROLIDINE;1-Boc-3-pyrrolidinyl Methanesulfonate;(3S)-N-Boc-3-[(methylsulphonyl)oxy]pyrrolidine;(R)-3-(Methylsulfonyloxy)pyrrolidine, N-BOC protected;(R)-3-(Methylsulphonyloxy)pyrrolidine, N-BOC protected;1-(tert-Butoxycarbonyl)pyrrolidin-3-yl methanesulfonate;2-(3-pyrrolidinyloxysulfonyl)acetic acid tert-butyl ester;(R)-3-(Methylsulphonyloxy)pyrrolidine, N-BOC protected 95+%
CBNumber: CB8479581
Molecular Formula: C10H19NO5S
Formula Weight: 265.33
MOL File: 141699-57-2.mol

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1-BOC-3-METHANESULFONYLOXYPYRROLIDINE Property

Boiling point:: 392.9±31.0 °C(Predicted)
Density: 1.25±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
form: solid
pka: -3.65±0.40(Predicted)

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Safety

Hazard Codes: Xi,T
Risk Statements: 25
Safety Statements: 45
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: ADE000053
Product name: (R)-3-Methanesulfonyloxy-pyrrolidine-1-carboxylic acid tert-butyl ester
Purity: Aldrich
Packaging: 1g
Price: $216
Updated: 2025/07/31

TRC

Product number: B809523
Product name: tert-Butyl3-((Methylsulfonyl)oxy)pyrrolidine-1-carboxylate
Packaging: 100mg
Price: $60
Updated: 2021/12/16

TRC

Product number: B809523
Product name: tert-Butyl3-((Methylsulfonyl)oxy)pyrrolidine-1-carboxylate
Packaging: 500mg
Price: $155
Updated: 2021/12/16

Matrix Scientific

Product number: 018173
Product name: 3-Methanesulfonyloxy-pyrrolidine-1-carboxylic acid tert-butyl ester
Packaging: 1g
Price: $63
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB130822
Product name: tert-Butyl 3-[(methylsulfonyl)oxy]pyrrolidine-1-carboxylate
Packaging: 1g
Price: $255
Updated: 2021/12/16

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1-BOC-3-METHANESULFONYLOXYPYRROLIDINE Chemical Properties,Usage,Production

Synthesis

83220-73-9

124-63-0

141699-57-2

GENERAL STEPS: To a stirred solution of 1-tert-butoxycarbonyl-3-hydroxypyrrolidine (16 g, 85.4 mmol) and triethylamine (19 mL, 129 mmol) in 130 mL of dichloromethane was added slowly and dropwise to a solution of methanesulfonyl chloride (10 mL, 129 mmol) in 20 mL of dichloromethane at 0 °C. After the dropwise addition was completed, the reaction mixture was continued to be stirred at room temperature for 2.5 hours. Upon completion of the reaction, the reaction was quenched with saturated aqueous sodium bicarbonate and extracted with dichloromethane. The organic phases were combined, dried over anhydrous sodium sulfate and concentrated under reduced pressure to give tert-butyl 3-methanesulfonyloxypyrrolidine-1-carboxylate (22.7 g, 100% yield) as a yellow solid.

References

[1] Patent: WO2013/97773, 2013, A1. Location in patent: Paragraph 0150
[2] Patent: US2016/168156, 2016, A1. Location in patent: Paragraph 0494; 0495
[3] Patent: KR2016/103390, 2016, A. Location in patent: Paragraph 0099; 0102
[4] Patent: CN107474024, 2017, A. Location in patent: Paragraph 0385; 0389; 0390; 0391
[5] Patent: US2016/200730, 2016, A1. Location in patent: Paragraph 0278; 0279

1-BOC-3-METHANESULFONYLOXYPYRROLIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-BOC-3-METHANESULFONYLOXYPYRROLIDINE Suppliers

China 51 Germany 3 India 2 Switzerland 2 United Kingdom 2 United States 15 Global 75

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
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Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
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Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
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Email: sales@chemreagents.com
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Shanghai Hanhong Scientific Co.,Ltd.

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NovoChemy Ltd.

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Shanghai Aladdin Bio-Chem Technology Co.,LTD

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Shanghai Raise Chemical Technology Co.,Ltd

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Bide Pharmatech Ltd.

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Chengdu Firster Pharmaceutical Co., Ltd.

Tel: 028-87078428 028-87074958
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View Lastest Price from 1-BOC-3-METHANESULFONYLOXYPYRROLIDINE manufacturers

Honest Joy Holdings Limited

Product: (R)-1-Boc-3-methanesulfonyloxypyrrolidine 141699-57-2
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98.3%
Supply Ability: 100 tons
Release date: 2022-01-26

Career Henan Chemical Co

Product: 1-BOC-3-METHANESULFONYLOXYPYRROLIDINE 141699-57-2
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 200kgs
Release date: 2020-01-28

141699-57-2, 1-BOC-3-METHANESULFONYLOXYPYRROLIDINERelated Search:

6-Boc-2-oxa-6-azaspiro[3.3]heptane tert-butyl 3-(2-tosylhydrazono)azetidine-1-carboxylate 1-Azetidinecarboxylic acid, 3-(2H-tetrazol-5-yl)-, 1,1-diMethylethyl ester 2-Methyl-7,8-dihydro-6H-pyrido[3,2-d]pyriMidine-5-carboxylic acid tert-butyl ester tert-butyl 2'-tert-butyl-7'-oxo-6',7'-dihydro-2'H-spiro[piperidine-4,5'-pyrano[3,2-c]pyrazole]-1-carboxylate (R)-3-HYDROXYMETHYL-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER (R)-N-Boc-3-aminomethylpiperidine tert-butyl 3-(3,5-difluoro-4-formylphenoxy)pyrrolidine-1-carboxylate (2S, 4R)-BOC-GAMMA-MSO-PROLINE METHYL ESTER N-Boc-trans-4-tosyloxy-L-proline methyl ester 1-BOC-3-METHANESULFONYLOXYPYRROLIDINE (2S,4R)-1-BOC-4-METHANESULFONYLOXY-PROLINE 1-BOC-3-(TOLUENE-4-SULFONYLOXY)-PYRROLIDINE (S)-1-Boc-3-methanesulfonyloxy-pyrrolidine (R)-1-BOC-3-METHANESULFONYLOXYPYRROLIDINE AKOS 90026 AKOS 338 AKOS 91497

1-(tert-Butoxycarbonyl)pyrrolidin-3-yl methanesulfonate

1-BOC-3-METHANESULFONYLOXYPYRROLIDINE

3-METHANESULFONYLOXY-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

(R)-3-(Methylsulphonyloxy)pyrrolidine

(R)-3-(Methylsulphonyloxy)pyrrolidine, N-BOC protected

138883

(R)-3-(Methylsulphonyloxy)pyrrolidine, N-BOC protected 95+%

2-(3-pyrrolidinyloxysulfonyl)acetic acid tert-butyl ester

(R)-3-(Methylsulfonyloxy)pyrrolidine, N-BOC protected

1-Pyrrolidinecarboxylic acid, 3-[(methylsulfonyl)oxy]-, 1,1-dimethylethyl ester

(3S)-N-Boc-3-[(methylsulphonyl)oxy]pyrrolidine

1-Boc-3-pyrrolidinyl Methanesulfonate

141699-57-2