Methyltetrazine-PEG8-NHS ester

Product Name: Methyltetrazine-PEG8-NHS ester
CAS No.: 2183440-34-6
Chemical Name: Methyltetrazine-PEG8-NHS ester
Synonyms: Methyltetrazine-PEG8-NHS ester;Methyltetrazine-PEG9-NHS ester;Methyltetrazine-O-PEG9-NHS ester;2,5-dioxopyrrolidin-1-yl 1-[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy]-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oate;Propanoic acid, 3-[[23-[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy]-3,6,9,12,15,18,21-heptaoxatricos-1-yl]oxy]-, 2,5-dioxo-1-pyrrolidinyl ester
CBNumber: CB84849614
Molecular Formula: C32H47N5O13
Formula Weight: 709.74
MOL File: 2183440-34-6.mol

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Methyltetrazine-PEG8-NHS ester Property

Boiling point:: 790.6±70.0 °C(Predicted)
Density: 1.29±0.1 g/cm3(Predicted)
pka: 1.67±0.10(Predicted)
InChIKey: HBEBYIRKMRTDSK-UHFFFAOYSA-N
SMILES: C(ON1C(=O)CCC1=O)(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOC1=CC=C(C2=NN=C(C)N=N2)C=C1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-23867
Product name: Methyltetrazine-PEG8-NHSester
Purity: 98%
Packaging: 10mg
Price: $220
Updated: 2021/12/16

BroadPharm

Product number: BP-23867
Product name: Methyltetrazine-PEG8-NHSester
Purity: 98%
Packaging: 25mg
Price: $430
Updated: 2021/12/16

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Methyltetrazine-PEG8-NHS ester Chemical Properties,Usage,Production

Description

Methyltetrazine-PEG8-NHS Ester is a PEG active NHS ester, which is very reactive with amine(NH2) cotaining entity. The hydrophilic PEG spacer is transferrable to the labeled molecule, reducing aggregation of labeled proteins stored in solution. Methyltetrazine enable click chemistry with TCO (trans-cycloctene).

Uses

Methyltetrazine-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Methyltetrazine-PEG8-NHS ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Methyltetrazine-PEG8-NHS ester Suppliers

China 19 United States 3 Global 22

Xi'an Confluore Biological Technology Co., Ltd.

Tel: +86-156-80926068 +86-15680926068
Email: 1924344760@qq.com
Country: China
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Alfa Chemistry

Tel: +1-5166625404;
Fax: 1-516-927-0118
Email: Info@alfa-chemistry.com
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TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
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Shaanxi Xinyan Bomei Biotechnology Co., Ltd.

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Beijing Jin Ming Biotechnology Co., Ltd.

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Tianjin Kaimu Chemical Technology Co., LTD

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Beijing Biocreative Technology Co., Ltd.

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Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd

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Shanghai Haohong Scientific Co., Ltd.

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Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-025-66113011 15955137747
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View Lastest Price from Methyltetrazine-PEG8-NHS ester manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Methyltetrazine-PEG8-NHS ester 2183440-34-6
Price: US $0.00/mg
Min. Order: 10mg
Purity: >99.00%
Supply Ability: 50mg
Release date: 2024-03-20

2183440-34-6, Methyltetrazine-PEG8-NHS esterRelated Search:

Methyl tetrazine OH Methyltetrazine-Acid Methyltetrazine-amido-PEG5-alkyne Methyltetrazine-PEG4-Azide Methyltetrazine-PEG12-NHS ester Methyltetrazine-propylamine HCl salt Methyltetrazine-NHS Ester

Methyltetrazine-PEG8-NHS ester

Propanoic acid, 3-[[23-[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy]-3,6,9,12,15,18,21-heptaoxatricos-1-yl]oxy]-, 2,5-dioxo-1-pyrrolidinyl ester

2,5-dioxopyrrolidin-1-yl 1-[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy]-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oate

Methyltetrazine-O-PEG9-NHS ester

Methyltetrazine-PEG9-NHS ester

2183440-34-6