ChemicalBook > CAS DataBase List > Methyltetrazine-PEG8-NHS ester
Methyltetrazine-PEG8-NHS ester
- Product Name
- Methyltetrazine-PEG8-NHS ester
- CAS No.
- 2183440-34-6
- Chemical Name
- Methyltetrazine-PEG8-NHS ester
- Synonyms
- Methyltetrazine-PEG8-NHS ester;2,5-dioxopyrrolidin-1-yl 1-[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy]-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oate;Propanoic acid, 3-[[23-[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy]-3,6,9,12,15,18,21-heptaoxatricos-1-yl]oxy]-, 2,5-dioxo-1-pyrrolidinyl ester
- CBNumber
- CB84849614
- Molecular Formula
- C32H47N5O13
- Formula Weight
- 709.74
- MOL File
- 2183440-34-6.mol
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Methyltetrazine-PEG8-NHS ester Property
- Boiling point:
- 790.6±70.0 °C(Predicted)
- Density
- 1.29±0.1 g/cm3(Predicted)
- pka
- 1.67±0.10(Predicted)
- InChIKey
- HBEBYIRKMRTDSK-UHFFFAOYSA-N
- SMILES
- C(ON1C(=O)CCC1=O)(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOC1=CC=C(C2=NN=C(C)N=N2)C=C1
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N-Bromosuccinimide Price
BroadPharm
- Product number
- BP-23867
- Product name
- Methyltetrazine-PEG8-NHSester
- Purity
- 98%
- Packaging
- 10mg
- Price
- $220
- Updated
- 2021/12/16
BroadPharm
- Product number
- BP-23867
- Product name
- Methyltetrazine-PEG8-NHSester
- Purity
- 98%
- Packaging
- 25mg
- Price
- $430
- Updated
- 2021/12/16
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Methyltetrazine-PEG8-NHS ester Chemical Properties,Usage,Production
Description
Methyltetrazine-PEG8-NHS Ester is a PEG active NHS ester, which is very reactive with amine(NH2) cotaining entity. The hydrophilic PEG spacer is transferrable to the labeled molecule, reducing aggregation of labeled proteins stored in solution. Methyltetrazine enable click chemistry with TCO (trans-cycloctene).
Uses
Methyltetrazine-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Methyltetrazine-PEG8-NHS ester Preparation Products And Raw materials
Raw materials
Preparation Products
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Methyltetrazine-PEG8-NHS ester Suppliers
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View Lastest Price from Methyltetrazine-PEG8-NHS ester manufacturers
Xian confluore Biological Technology Co., Ltd.
- Product
- Methyltetrazine-PEG8-NHS ester 2183440-34-6
- Price
- US $0.00/mg
- Min. Order
- 10mg
- Purity
- >99.00%
- Supply Ability
- 50mg
- Release date
- 2024-03-20
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