Methyltetrazine-Acid

Product Name: Methyltetrazine-Acid
CAS No.: 1380500-88-8
Chemical Name: Methyltetrazine-Acid
Synonyms: Methyltetrazine-Acid;Methyltetrazine Acid (CCT-1125);Methyltetrazine-Acid,Methyltetrazine-COOH;Benzeneacetic acid, 4-(6-methyl-1,2,4,5-tetrazin-3-yl)-;2-[4-(6-methyl-1,2,4,5-tetrazine-3-yl)phenyl]acetic acid
CBNumber: CB93345042
Molecular Formula: C11H10N4O2
Formula Weight: 230.2227
MOL File: 1380500-88-8.mol

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Methyltetrazine-Acid Property

storage temp.: 2-8°C
solubility: DMSO: 100 mg/mL (434.37 mM)
form: Solid
color: Pale purple to purple
InChI: InChI=1S/C11H10N4O2/c1-7-12-14-11(15-13-7)9-4-2-8(3-5-9)6-10(16)17/h2-5H,6H2,1H3,(H,16,17)
InChIKey: TZNOWMYISKGWCY-UHFFFAOYSA-N
SMILES: C1(CC(O)=O)=CC=C(C2=NN=C(C)N=N2)C=C1

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: M340788
Product name: Methyltetrazine-acid
Packaging: 5mg
Price: $45
Updated: 2021/12/16

BroadPharm

Product number: BP-22430
Product name: Methyltetrazine-acid
Purity: 95%
Packaging: 25mg
Price: $95
Updated: 2021/12/16

Chem-Impex

Product number: 35086
Product name: Methyltetrazineacid,95%(HPLC)
Purity: 95%(HPLC)
Packaging: 25MG
Price: $134.4
Updated: 2021/12/16

BroadPharm

Product number: BP-22430
Product name: Methyltetrazine-acid
Purity: 95%
Packaging: 100mg
Price: $195
Updated: 2021/12/16

Chem-Impex

Product number: 35086
Product name: Methyltetrazineacid,95%(HPLC)
Purity: 95%(HPLC)
Packaging: 100MG
Price: $268.8
Updated: 2021/12/16

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Methyltetrazine-Acid Chemical Properties,Usage,Production

Description

Methyltetrazine-Acid is a stable click chemistry building block. In the presence of activators (e.g. EDC, or HATU), it can be used to deriviate amine-containing molecule via a stable amide bond. Methyltetrazine enable fast click chemistry with TCO ((trans-cycloctene) under mild condition

Uses

Methyltetrazine-acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

Alkyl-Chain

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Methyltetrazine-Acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Methyltetrazine-Acid Suppliers

China 57 United States 5 Global 62

Huanuo Pharmaceutical Technology (Guangxi) Co., Ltd

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View Lastest Price from Methyltetrazine-Acid manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Methyltetrazine-Acid 1380500-88-8
Price: US $0.00/mg
Min. Order: 100mg
Purity: >99.00%
Supply Ability: 1g
Release date: 2024-03-20

1380500-88-8, Methyltetrazine-AcidRelated Search:

Methyltetrazine-PEG8-NHS ester Methyltetrazine-amido-PEG5-alkyne Methyltetrazine-PEG4-Azide Methyltetrazine-PEG12-NHS ester Methyltetrazine-NHS Ester Me-Tetrazine-PEG1-Alkyne Phosphonic acid,P-[(6-?methyl-?1,?2,?4,?5-?tetrazin-?3-?yl)?methyl]?-,diethyl ester

Methyltetrazine-Acid

Methyltetrazine-Acid,Methyltetrazine-COOH

Benzeneacetic acid, 4-(6-methyl-1,2,4,5-tetrazin-3-yl)-

2-[4-(6-methyl-1,2,4,5-tetrazine-3-yl)phenyl]acetic acid

Methyltetrazine Acid (CCT-1125)

1380500-88-8