HEMICHOLINIUM-3
- Product Name
- HEMICHOLINIUM-3
- CAS No.
- 312-45-8
- Chemical Name
- HEMICHOLINIUM-3
- Synonyms
- hc-3;Dibromide;hemicholine;hemicholiniumbromide;hemicholinium-3bromide;hemicholiniumdibromide;hemicholinium-3dibromide;2,2'-(4,4'-biphenylene)bis(2-hydroxy-4,4-dimethylmorpholinium) dibromide;2,2’-(4,4’-biphenylylene)bis(2-hydroxy-4,4-dimethyl-morpholiniudibromide;2,2’-(1,1’-biphenyl)-4,4’-diylbis(2-hydroxy-4,4-dimethyl-morpholinium)dibrom
- CBNumber
- CB8497048
- Molecular Formula
- C24H34N2O4.2Br
- Formula Weight
- 574.351
- MOL File
- 312-45-8.mol
HEMICHOLINIUM-3 Property
- Melting point:
- 180°; mp 226- 228° (dec)
- storage temp.
- Store at -20°C
- solubility
- ethanol: 1.3 mg/mL
- form
- solid
- color
- white
- Water Solubility
- Water : 33.33 mg/mL (58.03 mM; Need ultrasonic)
- Merck
- 13,4660
- BRN
- 5704458
- EPA Substance Registry System
- Morpholinium, 2,2'-[1,1'-biphenyl]-4,4'-diylbis[2-hydroxy-4,4-dimethyl-, dibromide (312-45-8)
Safety
- Hazard Codes
- T
- Risk Statements
- 23/24/25-36/37/38
- Safety Statements
- 26-36/37/39-45
- RIDADR
- UN 2811 6.1/PG 2
- WGK Germany
- 3
- RTECS
- QF2450000
- HazardClass
- 6.1(b)
- PackingGroup
- III
- Toxicity
- LD50 i.p. in female mice: 0.048-0.082 mg/kg (DiAugustine, Haarstad)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- H108
- Product name
- Hemicholinium-3
- Purity
- solid, ≥95% (HPLC)
- Packaging
- 100mg
- Price
- $90.3
- Updated
- 2024/03/01
- Product number
- H108
- Product name
- Hemicholinium-3
- Purity
- solid, ≥95% (HPLC)
- Packaging
- 500mg
- Price
- $452
- Updated
- 2024/03/01
- Product number
- H245658
- Product name
- Hemicholinium-3
- Packaging
- 10mg
- Price
- $80
- Updated
- 2021/12/16
- Product number
- INB0004498
- Product name
- HEMICHOLINIUM-3
- Purity
- 95.00%
- Packaging
- 100MG
- Price
- $597.77
- Updated
- 2021/12/16
- Product number
- INB0004498
- Product name
- HEMICHOLINIUM-3
- Purity
- 95.00%
- Packaging
- 500MG
- Price
- $725.22
- Updated
- 2021/12/16
HEMICHOLINIUM-3 Chemical Properties,Usage,Production
Uses
Acetylcholine stores depletor
Uses
Hemicholinium-3 has been used in the preparation of Krebs-HC-3 buffer to study its effects on choline uptake and choline acetyltransferase activity in differentiated human neuroblastoma (SK-N-SH) cells.
Uses
Research tool as cholinergic probe, to deplete acetylcholine stores.
Biochem/physiol Actions
Hemicholinium-3 plays a role in blocking the neuronal choline uptake thereby inhibiting acetylcholine synthesis in the brain.
HEMICHOLINIUM-3 Preparation Products And Raw materials
Raw materials
Preparation Products
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