1-METHYL-5-NITROIMIDAZOLE

Product Name: 1-METHYL-5-NITROIMIDAZOLE
CAS No.: 3034-42-2
Chemical Name: 1-METHYL-5-NITROIMIDAZOLE
Synonyms: 1-METHYL-5-NITROIMIDAZOLE;Metronidazole Impurity 4;1-methyl-5-nitro-imidazol;Imidazole, 1-methyl-5-nitro-;1H-Imidazole, 1-methyl-5-nitro-;1-Methyl-5-nitroimidazole >97.0% (HPLC)
CBNumber: CB8497336
Molecular Formula: C4H5N3O2
Formula Weight: 127.1
MOL File: 3034-42-2.mol

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1-METHYL-5-NITROIMIDAZOLE Property

Melting point:: 54-57 °C
Boiling point:: 328.9±15.0 °C(Predicted)
Density: 1.44±0.1 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Solid
pka: 2.13±0.10(Predicted)
color: Pale Yellow
BRN: 123550

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Safety

Hazard Codes: Xn
Risk Statements: 22
WGK Germany: 3
RTECS: NI7530000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 94489
Product name: 1-Methyl-5-nitroimidazole
Purity: >97.0% (HPLC)
Packaging: 1G
Price: $248
Updated: 2023/06/20

Sigma-Aldrich

Product number: 94489
Product name: 1-Methyl-5-nitroimidazole
Purity: >97.0% (HPLC)
Packaging: 5G
Price: $490
Updated: 2023/06/20

TRC

Product number: M323760
Product name: 1-Methyl-5-nitroimidazole
Packaging: 50g
Price: $835
Updated: 2021/12/16

TRC

Product number: M323760
Product name: 1-Methyl-5-nitroimidazole
Packaging: 1g
Price: $75
Updated: 2021/12/16

Matrix Scientific

Product number: 073688
Product name: 1-Methyl-5-nitroimidazole
Purity: 95+%
Packaging: 5g
Price: $95
Updated: 2021/12/16

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1-METHYL-5-NITROIMIDAZOLE Chemical Properties,Usage,Production

Chemical Properties

Pale Yellow Solid

Uses

1-Methyl-5-nitroimidazole is used in the synthesis of new 5-nitroimidazoles as potential antibacterial drugs via VNS procedure.

Synthesis

3034-38-6

3034-42-2

Example 2: 202 parts of 5-nitroimidazole were dissolved in 600 parts of 90% formic acid, followed by the addition of 250 parts of dimethyl sulfate. The reaction mixture was heated and kept for 6 hours. Upon completion of the reaction, the formic acid was removed by vacuum distillation. To the residue was added 420 parts of water and the mixture was cooled to 0°C to 5°C. The unreacted 5-nitroimidazole (60 parts) was separated by centrifugation. The pH of the mixture was adjusted to 10 using a 25% aqueous ammonia solution and the precipitate was precipitated at 0 °C to 5 °C. One hundred and thirty parts of 1-methyl-5-nitroimidazole were finally obtained with a melting point of 58°C to 60°C and a yield of 82% of the theoretical value (based on 4(5)-nitroimidazole).

References

[1] Patent: US4021442, 1977, A

1-METHYL-5-NITROIMIDAZOLE Preparation Products And Raw materials

Raw materials

Imidazole 4-Nitroimidazole Dimethyl sulfate

Preparation Products

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1-METHYL-5-NITROIMIDAZOLE Suppliers

Canada 1 China 85 Germany 2 India 3 South Korea 1 Switzerland 1 United Kingdom 1 United States 7 Global 101

J & K SCIENTIFIC LTD.

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View Lastest Price from 1-METHYL-5-NITROIMIDAZOLE manufacturers

Career Henan Chemical Co

Product: 1-METHYL-5-NITROIMIDAZOLE 3034-42-2
Price: US $1.00/KG
Min. Order: 1g
Purity: 98%
Supply Ability: 200kgs
Release date: 2020-01-09

3034-42-2, 1-METHYL-5-NITROIMIDAZOLERelated Search:

Metronidazole 1-(2-AMINOETHYL)-2-METHYL-5-NITROIMIDAZOLE DIHYDROCHLORIDE MONOHYDRATE 3-NITROIMIDAZO[1,2-A]PYRIDINE 1-(2-chloroethyl)-2-methyl-5-nitro-imidazol RONIDAZOLE Tinidazole 1,2-Dimethyl-5-nitroimidazole Ornidazole 1-METHYL-5-NITROIMIDAZOLE 4-Methyl-5-nitroimidazole 1-ETHYL-2-METHYL-4-NITRO-1H-IMIDAZOLE alpha,2-Dimethyl-5-nitro-1H-imidazole-1-ethanol Ternidazole 1-Methyl-5-nitro-1H-imidazole-2-methanol 2-Methyl-5-nitroimidazole Azathioprine 7-METHYL-3-NITROIMIDAZO[1,2-A]PYRIDINE 5-BROMO-2-METHYL-4-NITRO-1H-IMIDAZOLE

1H-Imidazole, 1-methyl-5-nitro-

1-methyl-5-nitro-imidazol

Imidazole, 1-methyl-5-nitro-

1-Methyl-5-nitroimidazole >97.0% (HPLC)

Metronidazole Impurity 4

1-METHYL-5-NITROIMIDAZOLE

3034-42-2

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