SCH 58261

Product Name: SCH 58261
CAS No.: 160098-96-4
Chemical Name: SCH 58261
Synonyms: CS-2187;SCH-58261;SCH 58261;Butanoicacid,4-bromo-5-oxo-,ethylester;Inhibitor,inhibit,SCH-58261,Adenosine Receptor,SCH 58261,P1 receptor;2-(Furan-2-yl)-7-phenethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyriMidin-5-aMine;7H-Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine, 2-(2-furanyl)-7-(2-phenylethyl)-;4-(furan-2-yl)-10-(2-phenylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(9),2,4,7,11-pentaen-7-amine;4-(furan-2-yl)-10-(2-phenylethyl)-3,5,6,8,10,11-hexaazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2,4,7,11-pentaen-7-amine
CBNumber: CB8497477
Molecular Formula: C18H15N7O
Formula Weight: 345.36
MOL File: 160098-96-4.mol

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SCH 58261 Property

Melting point:: 223 °C
Density: 1.54±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,2-8°C
solubility: DMSO: >10 mg/mL, soluble
form: solid
pka: 2.78±0.30(Predicted)
color: off-white

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Safety

WGK Germany: 3
HS Code: 2934.99.3000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: S4568
Product name: SCH 58261
Purity: ≥98% (HPLC), solid
Packaging: 5mg
Price: $200
Updated: 2024/03/01

Sigma-Aldrich

Product number: S4568
Product name: SCH 58261
Purity: ≥98% (HPLC), solid
Packaging: 25mg
Price: $304.8
Updated: 2024/03/01

TCI Chemical

Product number: C3599
Product name: SCH 58261
Packaging: 5MG
Price: $145
Updated: 2024/03/01

TCI Chemical

Product number: C3599
Product name: SCH 58261
Packaging: 25MG
Price: $532
Updated: 2024/03/01

Cayman Chemical

Product number: 19676
Product name: SCH 58261
Purity: ≥98%
Packaging: 1mg
Price: $32
Updated: 2024/03/01

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SCH 58261 Chemical Properties,Usage,Production

Uses

SCH 58261 is a potent and selective A2A adenosine receptor antagonist.

Definition

ChEBI: LSM-3822 is a member of triazolopyrimidines.

Biological Activity

Potent and selective A 2A adenosine receptor competitive antagonist (K i = 1.3 nM). Displays 323-, 53- and 100-fold selectivity over A 1 , A 2B and A 3 receptors, respectively.

Biochem/physiol Actions

SCH 58261 reduces the levels of TNF-α, Fas-L, Bax expression and activation of JNK-MAPK pathway. It has neuroprotective effects as it reduces demyelination of the neurons. SCH 58261 increases the concentration of secretion of dopamine and elicits locomotor sensitization, an attractive option in the possible treatment of Parkinson′s disease.

storage

Store at RT

SCH 58261 Preparation Products And Raw materials

Raw materials

Preparation Products

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SCH 58261 Suppliers

Americas 1 China 85 Europe 1 Germany 2 India 2 Japan 1 Switzerland 1 United Kingdom 2 United States 15 Global 110

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2922
Advantage: 55

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14103
Advantage: 59

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 19172
Advantage: 64

Hunan Hui Bai Shi Biotechnology Co., Ltd.

Tel: 0731-85526065 13308475853
Email: ivy@hnhbsj.com
Country: China
ProdList: 4552
Advantage: 62

Dalian Meilun Biotech Co., Ltd.

Tel: 0411-62910999 13889544652
Email: meilunui@163.com
Country: China
ProdList: 4727
Advantage: 58

Chengdu NoVi Biotechnology Co., Ltd.

Tel: 028-81458053
Fax: 028-81458053
Email: novibiotech@163.com sales@novi-biotech.com
Country: China
ProdList: 226
Advantage: 55

TOKYO CHEMICAL INDUSTRY CO., LTD.

Tel: 03-36680489
Fax: 03-3668-0520
Email: Sales-JP@TCIchemicals.com
Country: Japan
ProdList: 28387
Advantage: 80

TCI Europe

Tel: 320-37350700
Fax: +32 (0)37350701
Email: sales@tcieurope.eu
Country: Europe
ProdList: 23671
Advantage: 75

TCI AMERICA

Tel: 800-4238616
Fax: +1-888-520-1075 / +1-503-283-1987
Email: sales@tciamerica.com
Country: Americas
ProdList: 23653
Advantage: 75

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View Lastest Price from SCH 58261 manufacturers

Career Henan Chemical Co

Product: 7H-Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine, 2-(2-furanyl)-7-(2-phenylethyl)- 160098-96-4
Price: US $2.00/g
Min. Order: 1g
Purity: 95~99.9%
Supply Ability: 5KG
Release date: 2020-03-05

160098-96-4, SCH 58261Related Search:

SCH54292 7H-Pyrrolo[3,2-f]quinazoline-1,3-diaMine, N3-cyclopropyl-7-[[4-(1-Methylethyl)phenyl]Methyl]-, (Hydrochloride) (1:2) 2-(2-FURANYL)-7-[3-(4-METHOXYPHENYL)PROPYL]-7H-PYRAZOLO[4,3-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-5-AMINE R-(-)-7-Chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine, hydrochloride 6-(p-Nitrophenyl)pyrrolo[2,1-d][1,5]benzothiazepine 5,5-dioxide SCH772984 2-PROPYL-2H-PYRAZOL-3-YLAMINE 4-METHYL-2-PROPYL-2 H-PYRAZOL-3-YLAMINE SCH 58261 1H-1,2,4-Triazole-1-carboximidamide hydrochloride

CS-2187

SCH-58261;SCH 58261

7H-Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine, 2-(2-furanyl)-7-(2-phenylethyl)-

2-(Furan-2-yl)-7-phenethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyriMidin-5-aMine

4-(furan-2-yl)-10-(2-phenylethyl)-3,5,6,8,10,11-hexaazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2,4,7,11-pentaen-7-amine

4-(furan-2-yl)-10-(2-phenylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(9),2,4,7,11-pentaen-7-amine

Butanoicacid,4-bromo-5-oxo-,ethylester

Inhibitor,inhibit,SCH-58261,Adenosine Receptor,SCH 58261,P1 receptor

160098-96-4

C18H15N7O

Adenosine receptor