ChemicalBook > CAS DataBase List > SCH 58261

SCH 58261

Product Name: SCH 58261
CAS No.: 160098-96-4
Chemical Name: SCH 58261
Synonyms: CS-2187;SCH58261 ，S8104;SCH-58261;SCH 58261;SCH 58261, 10 mM in DMSO;SCH-58261, A2A antagonist;Butanoicacid,4-bromo-5-oxo-,ethylester;Inhibitor,inhibit,SCH-58261,Adenosine Receptor,SCH 58261,P1 receptor;2-(Furan-2-yl)-7-phenethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyriMidin-5-aMine;7H-Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine, 2-(2-furanyl)-7-(2-phenylethyl)-;2-(Furan-2-yl)-7-(2-phenylethyl)-7H-pyrazolo[4,3-e][1,2,4]-triazolo[1,5-c]pyrimidin-5-ylamine
CBNumber: CB8497477
Molecular Formula: C18H15N7O
Formula Weight: 345.36
MOL File: 160098-96-4.mol

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SCH 58261 Property

Melting point:: 223 °C
Density: 1.54±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,2-8°C
solubility: DMSO: >10 mg/mL, soluble
form: solid
pka: 2.78±0.30(Predicted)
color: off-white

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Safety

WGK Germany: 3
HS Code: 2934.99.3000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: S4568
Product name: SCH 58261
Purity: ≥98% (HPLC), solid
Packaging: 5mg
Price: $206
Updated: 2025/07/31

Sigma-Aldrich

Product number: S4568
Product name: SCH 58261
Purity: ≥98% (HPLC), solid
Packaging: 25mg
Price: $391.5
Updated: 2025/07/31

TCI Chemical

Product number: C3599
Product name: SCH 58261
Packaging: 5MG
Price: $131
Updated: 2025/07/31

TCI Chemical

Product number: C3599
Product name: SCH 58261
Packaging: 25MG
Price: $479
Updated: 2025/07/31

Cayman Chemical

Product number: 19676
Product name: SCH 58261
Purity: ≥98%
Packaging: 1mg
Price: $32
Updated: 2024/03/01

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SCH 58261 Chemical Properties,Usage,Production

Uses

SCH 58261 is a potent and selective A2A adenosine receptor antagonist.

Definition

ChEBI: LSM-3822 is a member of triazolopyrimidines.

Biological Activity

Potent and selective A 2A adenosine receptor competitive antagonist (K i = 1.3 nM). Displays 323-, 53- and 100-fold selectivity over A 1 , A 2B and A 3 receptors, respectively.

Biochem/physiol Actions

SCH 58261 reduces the levels of TNF-α, Fas-L, Bax expression and activation of JNK-MAPK pathway. It has neuroprotective effects as it reduces demyelination of the neurons. SCH 58261 increases the concentration of secretion of dopamine and elicits locomotor sensitization, an attractive option in the possible treatment of Parkinson′s disease.

storage

Store at RT

SCH 58261 Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from SCH 58261 manufacturers

Career Henan Chemical Co

Product: 7H-Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine, 2-(2-furanyl)-7-(2-phenylethyl)- 160098-96-4
Price: US $2.00/g
Min. Order: 1g
Purity: 95~99.9%
Supply Ability: 5KG
Release date: 2020-03-05

160098-96-4, SCH 58261Related Search:

SCH54292 7H-Pyrrolo[3,2-f]quinazoline-1,3-diaMine, N3-cyclopropyl-7-[[4-(1-Methylethyl)phenyl]Methyl]-, (Hydrochloride) (1:2) 2-(2-FURANYL)-7-[3-(4-METHOXYPHENYL)PROPYL]-7H-PYRAZOLO[4,3-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-5-AMINE R-(-)-7-Chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine, hydrochloride 6-(p-Nitrophenyl)pyrrolo[2,1-d][1,5]benzothiazepine 5,5-dioxide SCH772984 2-PROPYL-2H-PYRAZOL-3-YLAMINE 4-METHYL-2-PROPYL-2 H-PYRAZOL-3-YLAMINE SCH 58261 1H-1,2,4-Triazole-1-carboximidamide hydrochloride

CS-2187

SCH-58261;SCH 58261

7H-Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine, 2-(2-furanyl)-7-(2-phenylethyl)-

2-(Furan-2-yl)-7-phenethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyriMidin-5-aMine

4-(furan-2-yl)-10-(2-phenylethyl)-3,5,6,8,10,11-hexaazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2,4,7,11-pentaen-7-amine

4-(furan-2-yl)-10-(2-phenylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(9),2,4,7,11-pentaen-7-amine

Butanoicacid,4-bromo-5-oxo-,ethylester

Inhibitor,inhibit,SCH-58261,Adenosine Receptor,SCH 58261,P1 receptor

SCH-58261, A2A antagonist

SCH 58261, 10 mM in DMSO

SCH58261 ，S8104

2-(Furan-2-yl)-7-(2-phenylethyl)-7H-pyrazolo[4,3-e][1,2,4]-triazolo[1,5-c]pyrimidin-5-ylamine

160098-96-4

C18H15N7O

Adenosine receptor