SCH 58261
- Product Name
- SCH 58261
- CAS No.
- 160098-96-4
- Chemical Name
- SCH 58261
- Synonyms
- CS-2187;SCH-58261;SCH 58261;Butanoicacid,4-bromo-5-oxo-,ethylester;Inhibitor,inhibit,SCH-58261,Adenosine Receptor,SCH 58261,P1 receptor;2-(Furan-2-yl)-7-phenethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyriMidin-5-aMine;7H-Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine, 2-(2-furanyl)-7-(2-phenylethyl)-;4-(furan-2-yl)-10-(2-phenylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(9),2,4,7,11-pentaen-7-amine;4-(furan-2-yl)-10-(2-phenylethyl)-3,5,6,8,10,11-hexaazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2,4,7,11-pentaen-7-amine
- CBNumber
- CB8497477
- Molecular Formula
- C18H15N7O
- Formula Weight
- 345.36
- MOL File
- 160098-96-4.mol
SCH 58261 Property
- Melting point:
- 223 °C
- Density
- 1.54±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,2-8°C
- solubility
- DMSO: >10 mg/mL, soluble
- form
- solid
- pka
- 2.78±0.30(Predicted)
- color
- off-white
Safety
- WGK Germany
- 3
- HS Code
- 2934.99.3000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- S4568
- Product name
- SCH 58261
- Purity
- ≥98% (HPLC), solid
- Packaging
- 5mg
- Price
- $200
- Updated
- 2024/03/01
- Product number
- S4568
- Product name
- SCH 58261
- Purity
- ≥98% (HPLC), solid
- Packaging
- 25mg
- Price
- $304.8
- Updated
- 2024/03/01
- Product number
- C3599
- Product name
- SCH 58261
- Packaging
- 5MG
- Price
- $145
- Updated
- 2024/03/01
- Product number
- C3599
- Product name
- SCH 58261
- Packaging
- 25MG
- Price
- $532
- Updated
- 2024/03/01
- Product number
- 19676
- Product name
- SCH 58261
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $32
- Updated
- 2024/03/01
SCH 58261 Chemical Properties,Usage,Production
Uses
SCH 58261 is a potent and selective A2A adenosine receptor antagonist.
Definition
ChEBI: LSM-3822 is a member of triazolopyrimidines.
Biological Activity
Potent and selective A 2A adenosine receptor competitive antagonist (K i = 1.3 nM). Displays 323-, 53- and 100-fold selectivity over A 1 , A 2B and A 3 receptors, respectively.
Biochem/physiol Actions
SCH 58261 reduces the levels of TNF-α, Fas-L, Bax expression and activation of JNK-MAPK pathway. It has neuroprotective effects as it reduces demyelination of the neurons. SCH 58261 increases the concentration of secretion of dopamine and elicits locomotor sensitization, an attractive option in the possible treatment of Parkinson′s disease.
storage
Store at RT
SCH 58261 Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from SCH 58261 manufacturers
- Product
- 7H-Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine, 2-(2-furanyl)-7-(2-phenylethyl)- 160098-96-4
- Price
- US $2.00/g
- Min. Order
- 1g
- Purity
- 95~99.9%
- Supply Ability
- 5KG
- Release date
- 2020-03-05