ChemicalBook > CAS DataBase List > SCH 58261

SCH 58261

Product Name
SCH 58261
CAS No.
160098-96-4
Chemical Name
SCH 58261
Synonyms
CS-2187;SCH-58261;SCH 58261;Butanoicacid,4-bromo-5-oxo-,ethylester;Inhibitor,inhibit,SCH-58261,Adenosine Receptor,SCH 58261,P1 receptor;2-(Furan-2-yl)-7-phenethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyriMidin-5-aMine;7H-Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine, 2-(2-furanyl)-7-(2-phenylethyl)-;4-(furan-2-yl)-10-(2-phenylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(9),2,4,7,11-pentaen-7-amine;4-(furan-2-yl)-10-(2-phenylethyl)-3,5,6,8,10,11-hexaazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2,4,7,11-pentaen-7-amine
CBNumber
CB8497477
Molecular Formula
C18H15N7O
Formula Weight
345.36
MOL File
160098-96-4.mol
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SCH 58261 Property

Melting point:
223 °C
Density 
1.54±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,2-8°C
solubility 
DMSO: >10 mg/mL, soluble
form 
solid
pka
2.78±0.30(Predicted)
color 
off-white
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Safety

WGK Germany 
3
HS Code 
2934.99.3000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S4568
Product name
SCH 58261
Purity
≥98% (HPLC), solid
Packaging
5mg
Price
$200
Updated
2024/03/01
Sigma-Aldrich
Product number
S4568
Product name
SCH 58261
Purity
≥98% (HPLC), solid
Packaging
25mg
Price
$304.8
Updated
2024/03/01
TCI Chemical
Product number
C3599
Product name
SCH 58261
Packaging
5MG
Price
$145
Updated
2024/03/01
TCI Chemical
Product number
C3599
Product name
SCH 58261
Packaging
25MG
Price
$532
Updated
2024/03/01
Cayman Chemical
Product number
19676
Product name
SCH 58261
Purity
≥98%
Packaging
1mg
Price
$32
Updated
2024/03/01
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SCH 58261 Chemical Properties,Usage,Production

Uses

SCH 58261 is a potent and selective A2A adenosine receptor antagonist.

Definition

ChEBI: LSM-3822 is a member of triazolopyrimidines.

Biological Activity

Potent and selective A 2A adenosine receptor competitive antagonist (K i = 1.3 nM). Displays 323-, 53- and 100-fold selectivity over A 1 , A 2B and A 3 receptors, respectively.

Biochem/physiol Actions

SCH 58261 reduces the levels of TNF-α, Fas-L, Bax expression and activation of JNK-MAPK pathway. It has neuroprotective effects as it reduces demyelination of the neurons. SCH 58261 increases the concentration of secretion of dopamine and elicits locomotor sensitization, an attractive option in the possible treatment of Parkinson′s disease.

storage

Store at RT

SCH 58261 Preparation Products And Raw materials

Raw materials

Preparation Products

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SCH 58261 Suppliers

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View Lastest Price from SCH 58261 manufacturers

Career Henan Chemical Co
Product
7H-Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine, 2-(2-furanyl)-7-(2-phenylethyl)- 160098-96-4
Price
US $2.00/g
Min. Order
1g
Purity
95~99.9%
Supply Ability
5KG
Release date
2020-03-05

160098-96-4, SCH 58261Related Search:

SCH54292 7H-Pyrrolo[3,2-f]quinazoline-1,3-diaMine, N3-cyclopropyl-7-[[4-(1-Methylethyl)phenyl]Methyl]-, (Hydrochloride) (1:2) 2-(2-FURANYL)-7-[3-(4-METHOXYPHENYL)PROPYL]-7H-PYRAZOLO[4,3-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-5-AMINE R-(-)-7-Chloro-8-hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine, hydrochloride 6-(p-Nitrophenyl)pyrrolo[2,1-d][1,5]benzothiazepine 5,5-dioxide SCH772984 2-PROPYL-2H-PYRAZOL-3-YLAMINE 4-METHYL-2-PROPYL-2 H-PYRAZOL-3-YLAMINE SCH 58261 1H-1,2,4-Triazole-1-carboximidamide hydrochloride

  • CS-2187
  • SCH-58261;SCH 58261
  • 7H-Pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine, 2-(2-furanyl)-7-(2-phenylethyl)-
  • 2-(Furan-2-yl)-7-phenethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyriMidin-5-aMine
  • 4-(furan-2-yl)-10-(2-phenylethyl)-3,5,6,8,10,11-hexaazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2,4,7,11-pentaen-7-amine
  • 4-(furan-2-yl)-10-(2-phenylethyl)-3,5,6,8,10,11-hexazatricyclo[7.3.0.02,6]dodeca-1(9),2,4,7,11-pentaen-7-amine
  • Butanoicacid,4-bromo-5-oxo-,ethylester
  • Inhibitor,inhibit,SCH-58261,Adenosine Receptor,SCH 58261,P1 receptor
  • 160098-96-4
  • C18H15N7O
  • Adenosine receptor