ChemicalBook > CAS DataBase List > TERT-BUTYL 12-AMINO-4 7 10-TRIOXA-DODECA

TERT-BUTYL 12-AMINO-4 7 10-TRIOXA-DODECA

Product Name
TERT-BUTYL 12-AMINO-4 7 10-TRIOXA-DODECA
CAS No.
252881-74-6
Chemical Name
TERT-BUTYL 12-AMINO-4 7 10-TRIOXA-DODECA
Synonyms
tert-Butyl 3-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)propanoate;NH2-PEG3-C2-Boc;tert-butyl 3-(2-(2-(2-aminoethoxyl)ethoxy)ethoxy)propanoate;H2N-PEG3-tBu;Amino-PEG3-COOtBu;NH2-PEG3-C2-COOtBu;NH2-PEG3-CH2CH2COOtBu;H2N-PEG3-CH2CH2COOtBu;Amino-PEG3-t-Bu Ester;Amino-PEG3-tert-butyl ester
CBNumber
CB8497770
Molecular Formula
C13H27NO5
Formula Weight
277.36
MOL File
252881-74-6.mol
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TERT-BUTYL 12-AMINO-4 7 10-TRIOXA-DODECA Property

Boiling point:
358.5±27.0 °C(Predicted)
Density 
1.029±0.06 g/cm3(Predicted)
Flash point:
169.7 °C
storage temp. 
-20°C
form 
oil
pka
8.74±0.10(Predicted)
color 
Clear
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26
WGK Germany 
3
F 
10-34
HS Code 
2922500090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
83060
Product name
tert-Butyl 12-amino-4,7,10-trioxadodecanoate
Purity
technical,≥80%(T)
Packaging
1g
Price
$250
Updated
2024/03/01
Sigma-Aldrich
Product number
83060
Product name
tert-Butyl 12-amino-4,7,10-trioxadodecanoate
Purity
technical,≥80%(T)
Packaging
5G
Price
$395.2
Updated
2024/03/01
ChemPep
Product number
280402
Product name
H2N-PEG3-tBu
Packaging
1g
Price
$324
Updated
2021/12/16
BroadPharm
Product number
BP-20697
Product name
Amino-PEG3-t-butylester
Purity
98%
Packaging
500mg
Price
$90
Updated
2021/12/16
AK Scientific
Product number
0434AP
Product name
H2N-PEG3-tBu
Packaging
250mg
Price
$127
Updated
2021/12/16
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TERT-BUTYL 12-AMINO-4 7 10-TRIOXA-DODECA Chemical Properties,Usage,Production

Description

Amino-PEG3-t-butyl ester is a PEG linker containing an amino group with a t-butyl protected carboxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Uses

tert-Butyl 12-amino-4,7,10-trioxadodecanoate is generally used as a spacer or linker in bioconjugate chemistry. Some of its applications are:

  • Synthesis of the tetanus-toxin conjugate of MUC1 glycopeptide antigen, as a potential antitumor vaccine.
  • Synthesis of self-assembled monolayer-based surface-enhanced raman scattering (SERS) labels for immuno-SERS microscopy.
  • Synthesis of polycationic adamantane-based dendrons for cell imaging.
  • Synthesis of phthalocyanine (Pc)-peptide conjugates as potential fluorescence imaging agents for cancers overexpressing epidermal growth factor receptors (EGFR).

reaction suitability

reagent type: cross-linking reagent

TERT-BUTYL 12-AMINO-4 7 10-TRIOXA-DODECA Preparation Products And Raw materials

Raw materials

Preparation Products

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TERT-BUTYL 12-AMINO-4 7 10-TRIOXA-DODECA Suppliers

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View Lastest Price from TERT-BUTYL 12-AMINO-4 7 10-TRIOXA-DODECA manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Amino-PEG3-COOtBu 252881-74-6
Price
US $0.00/g
Min. Order
5g
Purity
>98.00%
Supply Ability
5g
Release date
2024-03-22
Career Henan Chemical Co
Product
TERT-BUTYL 12-AMINO-4 7 10-TRIOXA-DODECA 252881-74-6
Price
US $8.80/KG
Min. Order
1KG
Purity
97%-99%
Supply Ability
100kg
Release date
2019-07-04

252881-74-6, TERT-BUTYL 12-AMINO-4 7 10-TRIOXA-DODECARelated Search:

H2N-PEG3-CH2COOtBu N-BIOTINYL-3,6-DIOXAOCTANE-1,8-DIAMINE PENTAETHYLENE GLYCOL MPEG7-CH2CH2COOH 2,5,8,11-TETRAOXATRIDECANE-13-THIOL 2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47-Hexadecaoxanonatetracontan-49-ol MPEG4-CH2CH2COOH FMOC-18-AMINO-4,7,10,13,16-PENTAOXAOCTADECANOIC ACID Biotin-PEG3-propionic acid HO-PEG16-OH Decaethylene glycol alpha-MaleiMidopropionyl-oMega-succiniMidyl-12(ethylene glycol) FMOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID FMOC-GAMMA-ABU-OH 1-Azidohexaethylene Glycol alpha-aMine-oMega-propionic acid dodecaethylene glycol Biotin-PEG4-N3 1-AMINO-3,6,9-TRIOXAUNDECANYL-11-OL

  • [(+)-BIOTIN-PEG12-NHS ESTER]
  • H2N-PEG3-CH2CH2-t-butylester
  • tert-butyl 3-(2-(2-(2-aminoethoxyl)ethoxy)ethoxy)propanoate
  • Amino-PEG3-COOtBu
  • TERT-BUTYL 12-AMINO-4 7 10-TRIOXA-DODECA
  • H2N-PEG3-tBu
  • H2N-PEG3-CH2CH2COOtBu
  • tert-Butyl 12-aMino-4,7,10-trioxa-dodec
  • tert-butyl 3-{2-[2-(2-hydroxyethoxy)ethoxy]ethoxy}propanoate
  • 3-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]propionic acid tert-butyl ester
  • NH2-PEG3-CH2CH2COOtBu
  • tert-Butyl 3-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)propanoate
  • Propanoic acid,3-[2-[2-(2-aMinoethoxy)ethoxy]ethoxy]-, 1,1-diMethylethyl ester
  • tert-Butyl 12-amino-4,7,10-trioxadodecanoate technical, >=80% (T)
  • Amino-PEG3-tert-butyl ester
  • NH2-PEG3-C2-Boc
  • H2N-(CH2CH2O)3-CH2CH2COOt-Bu
  • Amino-PEG3-acid tert-Butyl Ester
  • Amino-PEG3-t-Bu Ester
  • H2N-PEG3-CH2CH2COOtBu/Propanoic acid, 3-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester
  • NH2-PEG3-C2-COOtBu
  • 12-Amino-4,7,10-Trioxdodecanoic acid tert-butyl ester
  • 252881-74-6
  • C13H27NO5
  • PEG-COOtBu
  • peg