3-O-Ethyl-L-ascorbic acid

Product Name: 3-O-Ethyl-L-ascorbic acid
CAS No.: 86404-04-8
Chemical Name: 3-O-Ethyl-L-ascorbic acid
Synonyms: ETHYL ASCORBIC ACID;VCE;vitaMin C ethyl ether;VC ethyl ether;3-O-Ethyl Ascorbyl Ether;3-0-Ethyl Ascorbic acid;Ethyl ascorbyl ether;(R)-5-((S)-1,2-dihydroxyethyl)-4-ethoxy-3-hydroxyfuran-2(5H)-one;(5r)-5-[(1s)-1,2-dihydroxyethyl]-4-ethoxy-3-hydroxy-5h-furan-2-one;LGB-VCE
CBNumber: CB8511566
Molecular Formula: C8H12O6
Formula Weight: 204.18
MOL File: 86404-04-8.mol

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3-O-Ethyl-L-ascorbic acid Property

Melting point:: 112.0 to 116.0 °C
Boiling point:: 551.5±50.0 °C(Predicted)
Density: 1.46±0.1 g/cm3(Predicted)
vapor pressure: 0-0Pa at 20-25℃
storage temp.: Sealed in dry,2-8°C
solubility: Methanol (Slightly), Water (Slightly)
form: Solid
pka: 8.89±0.40(Predicted)
color: White to Off-White
InChI: InChI=1S/C8H12O6/c1-2-13-7-5(11)8(12)14-6(7)4(10)3-9/h4,6,9-11H,2-3H2,1H3/t4-,6+/m0/s1
InChIKey: ZGSCRDSBTNQPMS-UJURSFKZSA-N
SMILES: O(CC)C1=C(O)C(=O)O[C@@H]1[C@H](CO)O
LogP: -0.8--0.64 at 20-25℃ and pH7
Surface tension: 69-72.4mN/m at 1g/L and 20℃

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Safety

HS Code: 2936.27.0000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical

Product number: E0926
Product name: 3-O-Ethyl-L-ascorbic Acid
Purity: >98.0%(HPLC)(T)
Packaging: 5g
Price: $42
Updated: 2024/03/01

TCI Chemical

Product number: E0926
Product name: 3-O-Ethyl-L-ascorbic Acid
Purity: >98.0%(HPLC)(T)
Packaging: 25g
Price: $144
Updated: 2024/03/01

TRC

Product number: E922013
Product name: 3-O-Ethyl-L-ascorbic Acid
Packaging: 100mg
Price: $85
Updated: 2021/12/16

Chem-Impex

Product number: 31932
Product name: 3-O-Ethyl-L-ascorbicacid,99%(HPLC)
Purity: 99%(HPLC)
Packaging: 1G
Price: $11.2
Updated: 2021/12/16

AK Scientific

Product number: J90968
Product name: 3-O-Ethyl-L-ascorbic Acid
Packaging: 1g
Price: $14
Updated: 2021/12/16

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3-O-Ethyl-L-ascorbic acid Chemical Properties,Usage,Production

Description

3-O-Ethyl ascorbate ether is a product of ascorbic acid-3-O-ethylation. It has a simple molecular structure and is easily absorbed by the skin. After entering the dermis through the stratum corneum of the skin, it is easily decomposed by the biological enzymes in the human body. The effect of ascorbic acid effectively solves the fat solubility problem of ascorbic acid, and is widely used in cosmetics as a whitening agent and antioxidant.

Uses

3-O-Ethyl-L-ascorbic Acid could be a useful stabilizing agent for a para-hydroxyacetophenone solution. It could be a useful stabilizing agent for a para-hydroxyacetophenone solution.

Definition

ChEBI: 3-O-ethyl-l-ascorbic acid (EA) is a butenolide. It is an l-ascorbic acid derivative with an ethyl group at the third carbon position.

Health effects

3-O-ethyl-L-ascorbic acid improves the molecules' stability and its transportation efficacy to the skin, being absorbed faster and better. Additionally, it is less irritating to the skin. Cosmetic case studies demonstrate that they have skin brightening, collagen stimulating, and antioxidant properties.

Mechanism of action

VC ethyl ether penetrates the stratum corneum to reach the melanocytes in the basal layer, inhibits tyrosinase activity, inhibits the formation of melanin, and restores melanin to colorless, thereby effectively whitening the skin. And Chemicalbook and VC ethyl ether can directly participate in the synthesis of collagen and repair skin cell activity after entering the dermis, increasing collagen, so that the skin becomes full and elastic, making the skin delicate and smooth.

Synthesis

The above 3-O-ethyl-5,6-O-isopropylideneascorbic acid 40g dissolved in 200ml of ethanol. 10g of cation-exchange resin was added and was refluxed for 2 hours. The catalyst was removed by an ion exchange resin and concentrated under reduced pressure. After drying, with ethyl acetate: hexane (3: 1) crystallization. After drying, obtained 33.3g 3-O-ethylascorbic acid, yield 94%. It was recrystallized in 100mL ethyl acetate giving 30.6g, yield 87%, mp: 112-114??C.

3-O-Ethyl-L-ascorbic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 3-O-Ethyl-L-ascorbic acid manufacturers

HebeiShuoshengImportandExportco.,Ltd

Product: 3-O-Ethyl-L-ascorbic acid 86404-04-8
Price: US $6.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 2000KG/Month
Release date: 2024-08-07

Jinan Finer Chemical Co., Ltd

Product: 3-O-Ethyl-L-ascorbic acid 86404-04-8
Price: US $0.00/Kg/Drum
Min. Order: 1KG
Purity: ≥99%
Supply Ability: 200mt/year
Release date: 2021-09-26

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: 3-O-Ethyl-L-ascorbic acid 86404-04-8
Price: US $80.00/kg
Min. Order: 1kg
Purity: 99
Supply Ability: 5000
Release date: 2024-04-23

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