Calcipotriol Monohydrate

Product Name: Calcipotriol Monohydrate
CAS No.: 147657-22-5
Chemical Name: Calcipotriol Monohydrate
Synonyms: Calcipotriol monohydrate CRS;CALCIPOTRIOL MONOHYDRATE;Calcipotriol (Calcipotriene) Monohydrate;(5Z,7E,22E,24S)-24-Cyclopropyl-9,10-secochola-5,7,10(19),22-tetraene-1α,3β,24-triol;(1R,3S,Z)-5-(2-((1R,3aS,7aR,E)-1-((2R,5S,E)-5-cyclopropyl-5-hydroxypent-3-en-2-yl)-7a-methyloctahydro-4H-inden-4-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol hydrate;(1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,2E,4S)-4-cyclopropyl-4-hydroxy-1-methyl-2-buten-1-yl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-1,3-Cyclohexanediol hydrate;(1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,2E,4S)-4-cyclopropyl-4-hydroxy-1-methyl-2-buten-1-yl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-1,3-Cyclohexanediol monohydrate;1,3-Cyclohexanediol,5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,2E,4S)-4-cyclopropyl-4-hydroxy-1-methyl-2-buten-1-yl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-,hydrate (1:1), (1R,3S,5Z)-
CBNumber: CB8588339
Molecular Formula: C27H42O4
Formula Weight: 430.63
MOL File: 147657-22-5.mol

More

Less

Calcipotriol Monohydrate Property

storage temp.: 4°C, protect from light, stored under nitrogen,unstable in solution, ready to use.
solubility: Practically insoluble in water, freely soluble in ethanol (96 per cent), slightly soluble in methylene chloride.
form: Powder
color: White to off-white
Stability:: Hygroscopic, Light sensitive
InChIKey: XBKHACNRWFKJNC-IZXATKCONA-N
SMILES: C[C@]12CCC/C(=C\C=C3\C[C@@H](O)C[C@H](O)C\3=C)/[C@]1([H])CC[C@]2([H])[C@H](C)/C=C/[C@H](C1CC1)O.O |&1:1,10,13,17,21,23,27,r|

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H310Fatal in contact with skin

Precautionary statements

P262Do not get in eyes, on skin, or on clothing.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P350IF ON SKIN: Gently wash with plenty of soap and water.

P310Immediately call a POISON CENTER or doctor/physician.

P322Specific measures (see …on this label).

P361Remove/Take off immediately all contaminated clothing.

P363Wash contaminated clothing before reuse.

P405Store locked up.

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 10009599
Product name: Calcipotriol (hydrate)
Packaging: 10mg
Price: $73
Updated: 2024/03/01

Cayman Chemical

Product number: 10009599
Product name: Calcipotriol (hydrate)
Packaging: 500mg
Price: $2505
Updated: 2024/03/01

Cayman Chemical

Product number: 10009599
Product name: Calcipotriol (hydrate)
Packaging: 50mg
Price: $324
Updated: 2024/03/01

Cayman Chemical

Product number: 10009599
Product name: Calcipotriol (hydrate)
Packaging: 100mg
Price: $575
Updated: 2024/03/01

TRC

Product number: C144230
Product name: CalcipotriolMonohydrate
Packaging: 25mg
Price: $825
Updated: 2021/12/16

More

Less

Calcipotriol Monohydrate Chemical Properties,Usage,Production

Description

Calcipotriol (hydrate) is a low-calcemic vitamin D receptor (VDR) agonist. Calcipotriol (hydrate) is about 200 times less potent in its effects on calcium metabolism than vitamin D (1,25[OH]D₃). Binding of calcipotriol (hydrate) to the VDR increases AP-1, a transcription factor important for keratinocyte differentiation, and reduces expression of JunB protein, a transcriptional activator in the inflammatory response. Calcipotriol (hydrate) also induces expression of thymic stromal lymphopoietin, which triggers T-cell differentiation in keratinocytes.

Chemical Properties

White or almost white, crystalline powder.

Uses

Calcipotriol monohydrate is a synthetic vitamin D3 analog with high affinity for the vitamin D receptor. It is used alone or in combination with betamethasone dipropionate for the treatment of psoriasis.

Definition

ChEBI: Calcipotriol hydrate is a hydrate that is the monohydrate form of calcipotriol. It is used in combination with betamethasone dipropionate, a corticosteroid, for the topical treatment of plaque psoriasis in adult patients. It has a role as an antipsoriatic. It contains a calcipotriol.

Calcipotriol Monohydrate Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Calcipotriol Monohydrate Suppliers

China 127 Denmark 1 France 1 India 10 Switzerland 1 United Kingdom 1 United States 11 Global 152

Jiangxi ravel Biotechnology Co.,Ltd

Tel: 400-880-2824 15608648206
Email: 1987516016@qq.com
Country: China
ProdList: 2816
Advantage: 58

Zhengzhou Kangshan Biological Co., Ltd.

Tel: +86-0371-55023472 +86-13663848272
Fax: 0371-55023472
Email: 2584787837@qq.com
Country: China
ProdList: 238
Advantage: 58

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6005
Advantage: 61

Wuhan Sunrise Technology Development Co., Ltd.

Tel: 27-027-83314682 13554138826
Fax: +86 (27) 8331-4682
Email: whsrtech@vip.163.com
Country: China
ProdList: 230
Advantage: 62

Wuhan Fortuna Chemical Co., Ltd

Tel: 027-59207852 13308628970
Fax: QQ3130921841
Email: buy@fortunachem.com
Country: China
ProdList: 2866
Advantage: 58

Dalian Meilun Biotech Co., Ltd.

Tel: 0411-62910999 13889544652
Email: meilunui@163.com
Country: China
ProdList: 4727
Advantage: 58

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7552
Advantage: 61

Nanjing Sunlida Biological Technology Co., Ltd.

Tel: 025-57798810
Fax: 025-57019371
Email: sales@sunlidabio.com
Country: China
ProdList: 3239
Advantage: 55

AdooQ BioScience, LLC

Tel: +1 (866) 930-6790
Fax: +1 (866) 333-9607
Email: info@adooq.com
Country: United States
ProdList: 2782
Advantage: 58

TargetMol Chemicals Inc.

Tel: 021-021-33632979 15002134094
Fax: 021-33632979
Email: marketing@targetmol.com
Country: China
ProdList: 7783
Advantage: 58

More

Less

View Lastest Price from Calcipotriol Monohydrate manufacturers

HangZhou RunYan Pharma Technology Co.,LTD.

Product: Calcipotriol Monohydrate 147657-22-5
Price: US $0.00-0.00/g
Min. Order: 10g
Purity: 95.5%
Supply Ability: 10000
Release date: 2024-11-08

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Calcipotriol Monohydrate 147657-22-5
Price: US $0.00-0.00/g/Bag
Min. Order: 1g
Purity: 97.5%
Supply Ability: 50g
Release date: 2021-07-30

BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.

Product: Calcipotriol 147657-22-5
Price: US $0.00/g
Min. Order: 1g
Purity: More Than 99%
Supply Ability: 100kg/Month
Release date: 2024-11-15

147657-22-5, Calcipotriol MonohydrateRelated Search:

(2E,4R)-4-[(1R,3aS,4E,7aR)-4-[(2E)-2-[(3S,5R)-3,5-Bis[[(tert-butyl)dimethylsilyl]oxy]-2-methylenecyclohexylidene]ethylidene]octahydro-7a-methyl-1H-inden-1-yl]-1-cyclopropyl-2-penten-1-one Carboplatin CALCIUM THIOGLYCOLATE TRIHYDRATE Calcipotriene Calcipotriene

CALCIPOTRIOL MONOHYDRATE

(1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,2E,4S)-4-cyclopropyl-4-hydroxy-1-methyl-2-buten-1-yl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-1,3-Cyclohexanediol hydrate

(5Z,7E,22E,24S)-24-Cyclopropyl-9,10-secochola-5,7,10(19),22-tetraene-1α,3β,24-triol

(1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,2E,4S)-4-cyclopropyl-4-hydroxy-1-methyl-2-buten-1-yl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-1,3-Cyclohexanediol monohydrate

1,3-Cyclohexanediol,5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,2E,4S)-4-cyclopropyl-4-hydroxy-1-methyl-2-buten-1-yl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-,hydrate (1:1), (1R,3S,5Z)-

Calcipotriol (Calcipotriene) Monohydrate

Calcipotriol monohydrate CRS

(1R,3S,Z)-5-(2-((1R,3aS,7aR,E)-1-((2R,5S,E)-5-cyclopropyl-5-hydroxypent-3-en-2-yl)-7a-methyloctahydro-4H-inden-4-ylidene)ethylidene)-4-methylenecyclohexane-1,3-diol hydrate

147657-22-5

C27H40O3H2O

API

API intermediates