1-Ethyl-2-pyrrolidone

Product Name: 1-Ethyl-2-pyrrolidone
CAS No.: 2687-91-4
Chemical Name: 1-Ethyl-2-pyrrolidone
Synonyms: 1-ETHYL-2-PYRROLIDINONE;N-Ethylpyrrolidone;N-Ethylpyrrolidinone;1-ETHYL-2-PYRROLIDONE;N-Ethyl-2-pyrrolidone (NEP);DDR;NEP crystal;N-Ethyl-2-pyrrolidinone;CAK;DDR1
CBNumber: CB8666318
Molecular Formula: C6H11NO
Formula Weight: 113.16
MOL File: 2687-91-4.mol

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1-Ethyl-2-pyrrolidone Property

Melting point:: 87.5-88.5 °C
Boiling point:: 97 °C/20 mmHg (lit.)
Density: 0.992 g/mL at 25 °C (lit.)
vapor pressure: 18Pa at 20℃
refractive index: n20/D 1.465(lit.)
Flash point:: 169 °F
storage temp.: Sealed in dry,Room Temperature
pka: -0.41±0.20(Predicted)
form: Liquid
color: Clear
PH: 8-9 (100g/l, H2O, 20℃)
explosive limit: 1.3-7.7%(V)
biological source: rabbit
Water Solubility: 1000g/L at 23℃
BRN: 107971
Specific Activity: 4.25-5.75nmol/min·mg
InChIKey: ZFPGARUNNKGOBB-UHFFFAOYSA-N
LogP: -0.2 at 20℃
CAS DataBase Reference: 2687-91-4(CAS DataBase Reference)
NIST Chemistry Reference: 1-Ethyl-2-pyrrolidinone(2687-91-4)
EPA Substance Registry System: 2-Pyrrolidinone, 1-ethyl- (2687-91-4)

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Safety

Hazard Codes: Xn,T
Risk Statements: 22-36-62-41-61
Safety Statements: 26-36-45-36/37/39-53
WGK Germany: 1
RTECS: UY5769250
Autoignition Temperature: 245°C (DIN 51794)
TSCA: Yes
HS Code: 29337900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SAB2900058
Product name: Anti-DDR1 (AB1) antibody produced in rabbit
Purity: affinity isolated antibody, buffered aqueous solution
Packaging: 50μG
Price: $703
Updated: 2024/03/01

Sigma-Aldrich

Product number: C7745
Product name: CDK7/Cyclin H1/MNAT1, active, His tagged human
Purity: PRECISIO? Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
Packaging: 10μg
Price: $521
Updated: 2024/03/01

Sigma-Aldrich

Product number: 146358
Product name: 1-Ethyl-2-pyrrolidone
Purity: 98%
Packaging: 100g
Price: $132
Updated: 2024/03/01

Sigma-Aldrich

Product number: 146358
Product name: 1-Ethyl-2-pyrrolidone
Purity: 98%
Packaging: 500g
Price: $455
Updated: 2024/03/01

Sigma-Aldrich

Product number: SAB5300117
Product name: Monoclonal Anti-DDR1 antibody produced in mouse
Purity: clone 2G4E12, ascites fluid
Packaging: 100μL
Price: $503
Updated: 2023/01/07

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1-Ethyl-2-pyrrolidone Chemical Properties,Usage,Production

Chemical Properties

N-Ethyl-2-pyrrolidone (NEP) is a colorless, clear liquid that serves as a low-volatility aprotic solvent classified as a reproductive toxicant. It is characterized by high solvency, low vapor pressure, and a low dielectric constant.

Uses

1-Ethyl-2-pyrrolidone was used to modify coir fiber (from Cocos nucifera) by photocuring.

Application

N-Ethyl-2-pyrrolidone is commonly used as a solvent. It has a low boiling point, which makes it suitable for use in low light and at constant pressure. It is also used as an intermediate in the preparation of polycarboxylic acid. It has been shown to be involved in both viscosity and hydrogen bonding.

Definition

ChEBI: 1-Ethyl-2-pyrrolidinone is a N-alkylpyrrolidine.

General Description

1-Ethyl-2-pyrrolidone is a transdermal absorption-enhancing compound and mechanism of its effect on multilammellar liposome of stratum corneum lipid has been studied.

Flammability and Explosibility

Non flammable

Biological Activity

CDK7 gene is a member of the cyclin-dependent protein kinase family th at is important regulators of cell cycle progression. CDK7 forms a trimeric complex with cyclin H and MAT1, which functions as a CDK-activating kinase (CAK). CDK7 is an essential component of the transcription factor TFIIH th at is involved in transcription initiation and DNA repair. CDK7 is thought to serve as a direct link between the regulation of transcription and the cell cycle.

Side effects

Neurotoxins - Acute Solvent Syndrome
Occupational Hepatotoxin - Secondary Hepatotoxin: Cases of possible toxic effects in an occupational setting depending on human ingestion or experimental poisoning of animals.
Reproductive toxin - A chemical that is toxic to the reproductive system, including offspring defects and damage to male or female reproductive function. Reproductive toxicity includes developmental effects.

Safety Profile

Moderately toxic by ingestion. An eye irritant. Combustible. When heated to decomposition it emits toxic fumes of NOx.

Toxics Screening Level

The initial threshold screening level (ITSL) for 1-ethyl-2-pyrrolidone (CAS # 2687-91-4) is 4.9 μg/m3 based on an annual averaging time.

1-Ethyl-2-pyrrolidone Preparation Products And Raw materials

Raw materials

Preparation Products

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1-Ethyl-2-pyrrolidone Suppliers

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View Lastest Price from 1-Ethyl-2-pyrrolidone manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: N-Ethyl-2-pyrrolidone 2687-91-4
Price: US $30.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 5000kg/Month
Release date: 2024-04-29

Hebei Mojin Biotechnology Co.,Ltd

Product: 1-Ethyl-2-pyrrolidone 2687-91-4
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2024-05-22

Hebei Mojin Biotechnology Co.,Ltd

Product: 1-Ethyl-2-pyrrolidone 2687-91-4
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2024-05-24

2687-91-4, 1-Ethyl-2-pyrrolidoneRelated Search:

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Drd1

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