ChemicalBook > CAS DataBase List > 4-Chloro-2,3-dimethylpyridine 1-oxide

4-Chloro-2,3-dimethylpyridine 1-oxide

Product Name
4-Chloro-2,3-dimethylpyridine 1-oxide
CAS No.
59886-90-7
Chemical Name
4-Chloro-2,3-dimethylpyridine 1-oxide
Synonyms
NSC 27526;nsc 275262;Lansoprazole-15;4-Chloro-2,3-dimethy;Rabeprazole Impurity 40;Lansoprazole Impurity 57;Lansoprazole Impurity B-9;Lansoprazole EP Impurity 16;3-DiMethyl-4-chloropyridine N-oxide;2,3-DiMethyl-4-chloropyridne-n-oxide
CBNumber
CB8670430
Molecular Formula
C7H8ClNO
Formula Weight
157.6
MOL File
59886-90-7.mol
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4-Chloro-2,3-dimethylpyridine 1-oxide Property

Melting point:
103-105°C
Boiling point:
338.5°C
Density 
1.19
vapor pressure 
0.346Pa at 25℃
Flash point:
158.5°C
storage temp. 
Room temperature.
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
pka
1.28±0.10(Predicted)
color 
Pale Yellow to Light Beige
LogP
0.4 at 25℃
CAS DataBase Reference
59886-90-7(CAS DataBase Reference)
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Safety

Safety Statements 
24/25
HS Code 
29333990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H341Suspected of causing genetic defects

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T138479
Product name
4-CHLORO-2,3-DIMETHYLPYRIDINE 1-OXIDE
Purity
AldrichCPR
Packaging
5MG
Price
$29.8
Updated
2024/03/01
TCI Chemical
Product number
C2820
Product name
4-Chloro-2,3-dimethylpyridine N-Oxide
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$48
Updated
2024/03/01
TCI Chemical
Product number
C2820
Product name
4-Chloro-2,3-dimethylpyridine N-Oxide
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$166
Updated
2024/03/01
Usbiological
Product number
268163
Product name
4-Chloro-2,3-dimethylpyridine N-oxide
Packaging
5g
Price
$326
Updated
2021/12/16
TRC
Product number
C365450
Product name
4-Chloro-2,3-dimethylpyridine N-Oxide
Packaging
5g
Price
$75
Updated
2021/12/16
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4-Chloro-2,3-dimethylpyridine 1-oxide Chemical Properties,Usage,Production

Chemical Properties

Pale Yellow Solid

Uses

An intermediate in the synthesis of rabeprazole (R070500).

Synthesis

83.0 g (0.49 mol) of 4-nitro-2,3-dimethylpyridine N-oxide and 90 g (1.54 mol) of NaCl were admixed with 1350 ml of CH3CN, 180 ml of aq. HCl (36%) and 16.6 g of benzyltributylammonium chloride, and the resulting suspension was boiled under reflux with stirring for 12 h. The resulting reaction mixture was adjusted to PH=9 using 350 ml of 20% NaOH, wherefor the existing precipitate largely dissolved. The organic phase was separated off, water was added to the aqueous phase until the precipitate had completely dissolved, and it was subsequently extracted using dichloromethane. The organic phases were combined and the solvent was removed under reduced pressure. 76.6 g (98.5%) of 4-Chloro-2,3-dimethylpyridine 1-oxide were obtained.

4-Chloro-2,3-dimethylpyridine 1-oxide Preparation Products And Raw materials

Raw materials

Hydrogen peroxide Ethyl acetate Hydrochloric acid Nitric acid Dichloromethane Acetic acid 2,3-Lutidine Sulfuric acid

Preparation Products

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View Lastest Price from 4-Chloro-2,3-dimethylpyridine 1-oxide manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd
Product
4-Chloro-2,3-dimethylpyridine1-oxide 59886-90-7
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 ton
Release date
2024-12-03
Dideu Industries Group Limited
Product
4-Chloro-2,3-dimethylpyridine 1-oxide 59886-90-7
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons min
Release date
2021-09-03
Career Henan Chemical Co
Product
4-Chloro-2,3-dimethylpyridine1-oxide 59886-90-7
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
KG/T
Release date
2019-12-17

59886-90-7, 4-Chloro-2,3-dimethylpyridine 1-oxideRelated Search:

ETHYLENE OXIDE Aluminum oxide Zinc oxide 4-Chloropyridinium chloride 2,6-Lutidine Chlorodimethylphenylsilane tert-Butyldimethylsilyl chloride Clopidol Iron oxide DIMETHYLTHEXYLSILYL CHLORIDE NITRIC OXIDE Pyridine-N-oxide CHLORODIMETHYLVINYLSILANE 2,3-Lutidine Sodium oxide (Diethoxymethyl)diphenylphosphine oxide 4-Chloropyridine N-oxide 2,3-Dimethylpyridine-N-oxide

  • 4-Chloro-2,3-dimethylpyridine-N-oxide ,98%
  • 4-Chloro-2,3-dimethy
  • 3-DiMethyl-4-chloropyridine N-oxide
  • 4-chloro-2,3-diMethyl-1$l^{5}-pyridin-1-one
  • 2,3-DiMethyl-4-chloropyridne-n-oxide
  • 4-Chloro-2,3-lutidine N-oxide, 4-Chloro-2,3-dimethylpyridinium-1-olate
  • nsc 275262
  • 2,3-DIMETHYL-4-CHLOROPYRIDINE-N-OXIDE
  • 4-Chloro-2,3-Dimethyl Pyridine-N-Oxide 99%
  • Pyridine-N-oxide, 4-chloro-2,3-dimethyl
  • 4-CHLORO-2,3-DIMETHYL-PYRIDINE 1-OXIDE
  • 4-CHLORO-2,3-DIMETHYLPYRIDINE-N-OXIDE
  • 2,3-Dimethyl-4-Chloro Pyridine-1-Oxide
  • NSC 27526
  • Pyridine, 4-chloro-2,3-dimethyl-, 1-oxide
  • Lansoprazole Impurity B-9
  • Lansoprazole-15
  • Lansoprazole Impurity 57
  • 4-Chloro-2,3-dimethylpyridine N-Oxide &gt
  • 4-Chloro-2,3-dimethylpyridine 1-oxide ISO 9001：2015 REACH
  • 59886-90-7 4-Chloro-2,3-dimethylpyridine 1-oxide
  • Rabeprazole Impurity 40
  • Lansoprazole EP Impurity 16
  • 59886-90-7
  • Intermediates of Rabeprazole
  • Heterocycles
  • Nitric Oxide Reagents
  • Heterocycle-Pyridine series
  • Rabeprazole
  • PHARMACEUTICAL INTERMEDIATES
  • Pyridines
  • bc0001