Risks to the environment
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Climbazole

Risks to the environment
Product Name
Climbazole
CAS No.
38083-17-9
Chemical Name
Climbazole
Synonyms
CLIMBAZOL;baypival;Crinipan AD;1-[(4-Chlorophenoxy)(tert-butylcarbonyl)Methyl]iMidazole;1-(4-Chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethylbutan-2-one;BAYSAN;MEB-6401;bay-e6975;Diadimefon;CLIMBAZOLE
CBNumber
CB8671477
Molecular Formula
C15H17ClN2O2
Formula Weight
292.76
MOL File
38083-17-9.mol
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Climbazole Property

Melting point:
96-100°C
Boiling point:
447.5±40.0 °C(Predicted)
Density 
1.17±0.1 g/cm3(Predicted)
vapor pressure 
0.001Pa at 25℃
refractive index 
1.54
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Insoluble in water
pka
5.66±0.22(Predicted)
color 
White to Almost white
Water Solubility 
58mg/L at 25℃
BRN 
618020
InChIKey
OWEGWHBOCFMBLP-UHFFFAOYSA-N
LogP
3.83 at 25℃
CAS DataBase Reference
38083-17-9(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn,N
Risk Statements 
22-50/53
Safety Statements 
60-61
RIDADR 
UN 3077
WGK Germany 
3
RTECS 
EL7085000
HS Code 
29332900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H410Very toxic to aquatic life with long lasting effects

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
36127
Product name
Climbazole
Purity
PESTANAL?, analytical standard
Packaging
100mg
Price
$106
Updated
2024/03/01
Sigma-Aldrich
Product number
1135600
Product name
Climbazole
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
400mg
Price
$436
Updated
2024/03/01
TCI Chemical
Product number
C2025
Product name
Climbazole
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$60
Updated
2024/03/01
TCI Chemical
Product number
C2025
Product name
Climbazole
Purity
>98.0%(HPLC)(T)
Packaging
500g
Price
$483
Updated
2024/03/01
Cayman Chemical
Product number
27968
Product name
(±)-Climbazole
Packaging
50g
Price
$78
Updated
2024/03/01
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Climbazole Chemical Properties,Usage,Production

Risks to the environment

Climbazole (CBZ) is an emerging recalcitrant contaminant in wastewater, which has severe toxic effects on aquatic organisms.

Description

(±)-Climbazole is an imidazole antifungal agent. It inhibits the growth of C. albicans (MIC = 0.29 μg/ml), as well as clinical isolates of M. pachydermatis (MICs = <0.06-1 μg/ml) and M. furfur (MICs = <0.06-0.5 μg/ml) in vitro. It also reduces the size of Malassezia populations on the skin of naturally infected dogs when used at a dose of 2% in shampoo. (±)-Climbazole (80 mg/kg) increases the levels of cytochrome P450 in rat liver. Formulations containing climbazole have been used in the treatment of dandruff.

Chemical Properties

White Solid

Uses

Climbazole is an imidazole antifungal agent that can provide anti-dandruff benefits when incorporated into a shampoo matrix. s assay and did not induce micronuclei in human lymphocytes.

Definition

ChEBI: 1-(4-chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethylbutan-2-one is a ketone that is butan-2-one substituted by a 4-chlorophenoxy and a 1H-imidazol-1-yl group at position 1 and 2 methyl groups at position 3. It is a member of monochlorobenzenes, a member of imidazoles, an aromatic ether, a ketone and a hemiaminal ether.

Hazard

Moderately toxic by ingestion. Low toxicity by skin contact.

Flammability and Explosibility

Non flammable

Side effects

May cause localized irritation of the skin with symptoms including redness, rashes and itching.

Climbazole Preparation Products And Raw materials

Raw materials

Preparation Products

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Climbazole Suppliers

Hefei TNJ Chemical Industry Co.,Ltd.
Tel
551-65418679 15837135945
Fax
0551-65418697
Email
info@tnjchem.com
Country
China
ProdList
1889
Advantage
62
Changzhou Hengda Biotechnology Co., Ltd
Tel
0519-0519-85265229 18015028189
Fax
0519-85266229
Email
sales@hengdabio.net
Country
China
ProdList
48
Advantage
55
Neostar United (Changzhou) Industrial Co., Ltd.
Tel
0519-85551759 13376258932
Fax
0519-85557389
Email
project@neostarunited.com
Country
China
ProdList
150
Advantage
58
Hubei Harvest chemical Co.,Ltd.
Tel
13277936479
Email
2381448056@qq.com
Country
China
ProdList
552
Advantage
58
Tianjin Zhongxin Chemtech Co., Ltd.
Tel
022-66880623
Fax
86(0)22-66880086
Email
sales@tjzxchem.com
Country
China
ProdList
614
Advantage
60
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
Chembest Research Laboratories Limited
Tel
021-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6013
Advantage
61
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2341
Advantage
56
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
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View Lastest Price from Climbazole manufacturers

BLiT (Hefei)Chemical Co.,Ltd
Product
Climbazole 38083-17-9
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100TONS
Release date
2024-03-27
Shandong Juchuang Chemical Co., LTD
Product
Climbazole 38083-17-9
Price
US $23.00-14.00/kg
Min. Order
500kg
Purity
99.9
Supply Ability
200ton
Release date
2024-03-14
airuikechemical co., ltd.
Product
Climbazole 38083-17-9
Price
US $0.00-0.00/Kg
Min. Order
1Kg
Purity
99.9%
Supply Ability
20 tons
Release date
2024-03-13

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