REVERSIN 121

Product Name: REVERSIN 121
CAS No.: 174630-04-7
Chemical Name: REVERSIN 121
Synonyms: REVERSIN 121;BOC-ASP(OBZL)-LYS(Z)-OTBU;L-Lysine, N-[(1,1-dimethylethoxy)carbonyl]-L-α-aspartyl-N6-[(phenylmethoxy)carbonyl]-, 2-(1,1-dimethylethyl) 1-(phenylmethyl) ester
CBNumber: CB8699257
Molecular Formula: C34H47N3O9
Formula Weight: 641.75
MOL File: Mol file

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REVERSIN 121 Property

Boiling point:: 786.8±60.0 °C(Predicted)
Density: 1.163±0.06 g/cm3(Predicted)
storage temp.: −20°C
solubility: DMSO or ethanol: soluble
form: powder
pka: 10.75±0.46(Predicted)
color: white

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: R1276
Product name: Reversin 121
Purity: ≥97% (HPLC), powder
Packaging: 3mg
Price: $583
Updated: 2024/03/01

Cayman Chemical

Product number: 18603
Product name: Reversin 121
Purity: ≥98%
Packaging: 500μg
Price: $34
Updated: 2024/03/01

Cayman Chemical

Product number: 18603
Product name: Reversin 121
Purity: ≥98%
Packaging: 1mg
Price: $59
Updated: 2024/03/01

Cayman Chemical

Product number: 18603
Product name: Reversin 121
Purity: ≥98%
Packaging: 5mg
Price: $198
Updated: 2024/03/01

American Custom Chemicals Corporation

Product number: PEP0004566
Product name: REVERSIN 121
Purity: 95.00%
Packaging: 3MG
Price: $874.34
Updated: 2021/12/16

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REVERSIN 121 Chemical Properties,Usage,Production

Description

Reversin 121 is a hydrophobic peptide chemosensitizer that can reverse P-glycoprotein-mediated multidrug resistance. It binds to the P-glycoprotein multidrug transporter (MDR1) with a K_d value of 77 nM. Reversin 121 modulates P-glycoprotein ATPase activity in Sf9 insect cell membranes expressing human MDR1, plasma membrane vesicles from multidrug-resistant cells, and reconstituted proteoliposomes as well as in a variety of MDR1-expressing intact tumor cells.

Uses

Reversin 121 has been used to determine the activity of P-glycoprotein in human retinal pigment epithelium.

General Description

Reversin 121 is an analog of reversin and a dipeptide derivative.

Biochem/physiol Actions

Peptide chemosensitizer, inhibitor of P-glycoprotein.

REVERSIN 121 Preparation Products And Raw materials

Raw materials

Preparation Products

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REVERSIN 121 Suppliers

China 22 Switzerland 2 United Kingdom 3 United States 5 Global 32

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
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Shanghai EFE Biological Technology Co., Ltd.

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Hangzhou Peptidego Biotech Co.,Ltd.

Tel: 0571-87213919
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Shanghai Hongye Biotechnology Co. Ltd

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ChemeGen(Shanghai) Biotechnology Co.,Ltd.

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MedBioPharmaceutical Technology Inc

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TargetMol Chemicals Inc.

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Hangzhou Sinoda Pharmaceutical Technology Co. LTD

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Aladdin Scientific

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174630-04-7, REVERSIN 121Related Search:

REVERSIN 121

BOC-ASP(OBZL)-LYS(Z)-OTBU

L-Lysine, N-[(1,1-dimethylethoxy)carbonyl]-L-α-aspartyl-N6-[(phenylmethoxy)carbonyl]-, 2-(1,1-dimethylethyl) 1-(phenylmethyl) ester

174630-04-7

C34H47N3O9

Enzymes, Inhibitors, and Substrates

Enzyme Inhibitors

Enzyme Inhibitors by Enzyme

P-Glycoprotein

P to Q

Biochemicals and Reagents

BioChemical