ChemicalBook > CAS DataBase List > PREGNENOLONE SULFATE SODIUM SALT

PREGNENOLONE SULFATE SODIUM SALT

Product Name
PREGNENOLONE SULFATE SODIUM SALT
CAS No.
1852-38-6
Chemical Name
PREGNENOLONE SULFATE SODIUM SALT
Synonyms
Pregnenolone 3-Sulfate;PREGNENOLONE SULFATE SODIUM;Pregnenolone-3-sulfate Sodium;SodiuM Pregnenolone-d4 Sulfate;5-Pregnen-3β-ol-20-one sulfate;Pregnenolone sulphate Na+ salt;PREGNENOLONE SULFATE SODIUM SALT;PREGNENOLONE SULPHATE, SODIUM SALT;Pregnenolone-3-sulfate SodiuM Salt;3-Hydroxypregn-5-en-20-one sulfate
CBNumber
CB8701970
Molecular Formula
C21H31NaO5S
Formula Weight
418.52
MOL File
1852-38-6.mol
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PREGNENOLONE SULFATE SODIUM SALT Property

Melting point:
192 °C(lit.)
storage temp. 
Store at -20°C
solubility 
methanol and water: 1.93 mg/mL
form 
A crystalline solid
color 
White to off-white
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
P162
Product name
Pregnenolone sulfate sodium salt
Packaging
25mg
Price
$16.56
Updated
2024/03/01
Sigma-Aldrich
Product number
P162
Product name
Pregnenolone sulfate sodium salt
Packaging
100mg
Price
$84.7
Updated
2024/03/01
Cayman Chemical
Product number
21004
Product name
Pregnenolone sulfate (sodium salt)
Purity
≥95%
Packaging
50mg
Price
$50
Updated
2024/03/01
Cayman Chemical
Product number
21004
Product name
Pregnenolone sulfate (sodium salt)
Purity
≥95%
Packaging
100mg
Price
$80
Updated
2024/03/01
Cayman Chemical
Product number
21004
Product name
Pregnenolone sulfate (sodium salt)
Purity
≥95%
Packaging
250mg
Price
$163
Updated
2024/03/01
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PREGNENOLONE SULFATE SODIUM SALT Chemical Properties,Usage,Production

Description

Pregnenolone sulfate is a metabolite of the natural steroid hormone pregnenolone . Pregnenolone sulfate modulates NMDA receptor responses to exogenously applied glutamate and stimulates transient receptor potential melastatin 3 (TRPM3).

Uses

Pregnenolone sulfate sodium salt has been used as sigma-1 receptor (σ1R) agonist. It has also been used in the stimulation and as a ligand for transient receptor potential melastatin-3 (TRPM3).

Uses

Pregnenolone Sulfate Sodium Salt, is a metabolite of Pregnenolone (P712200). It is also a neuroactive steroid, a potent and efficacious modulators of the GABAA receptor.

Biochem/physiol Actions

Pregnenolone sulfate is a neurosteroid and a neuromodulator. It is involved in the stimulation of N-methyl-D-aspartate receptor (NMDA), γ-Aminobutyric acid type A (GABAA?) and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA-kainate). It activates transient receptor potential melastatin (TRPM3) which is a calcium-permeable ion channel. It improves schizophrenia and behavioral anomalies by modulating NMDA mediated Ser/Thr kinase - glycogen synthase kinase 3 β (AKT/GSK3β) signaling pathway.

storage

Store at +4°C

PREGNENOLONE SULFATE SODIUM SALT Preparation Products And Raw materials

Raw materials

Preparation Products

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PREGNENOLONE SULFATE SODIUM SALT Suppliers

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1852-38-6, PREGNENOLONE SULFATE SODIUM SALTRelated Search:


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  • 3β-Hydroxy-5-pregnen-20-one 3-sulfate, 3-Hydroxypregn-5-en-20-one sulfate, 5-Pregnen-3β-ol-20-one sulfate
  • SodiuM Pregnenolone-d4 Sulfate
  • Pregnenolone-3-sulfate SodiuM Salt
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  • 5-Pregnen-3β-ol-20-one sulfate
  • Pregnenolone sulphate Na+ salt
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  • C21H31O5SNa
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