DIMETHISTERONE
- Product Name
- DIMETHISTERONE
- CAS No.
- 79-64-1
- Chemical Name
- DIMETHISTERONE
- Synonyms
- Ovin;P 5048;Lutogan;Secrosteron;DIMETHISTERONE;DIMETHISTERONE USP/EP/BP;6α,21-Dimethylethisterone;6α-Methyl-17-(1-propynyl)testosterone;17β-Hydroxy-6α-methyl-17-(1-propynyl)androst-4-en-3-one;Androst-4-en-3-one,17-hydroxy-6-methyl-17-(1-propynyl)-, (6a,17b)-
- CBNumber
- CB8702265
- Molecular Formula
- C23H32O2
- Formula Weight
- 340.5
- MOL File
- 79-64-1.mol
DIMETHISTERONE Property
- Melting point:
- 102°
- alpha
- D20 +10° (c = 1 in chloroform)
- Boiling point:
- 416.28°C (rough estimate)
- Density
- 1.0555 (rough estimate)
- refractive index
- 1.4480 (estimate)
- pka
- 13.03±0.70(Predicted)
- EPA Substance Registry System
- Dimethisterone (79-64-1)
N-Bromosuccinimide Price
- Product number
- D460430
- Product name
- Dimethisterone
- Packaging
- 10mg
- Price
- $150
- Updated
- 2021/12/16
- Product number
- API0002385
- Product name
- DIMETHISTERONE ANHYDROUS
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $496.99
- Updated
- 2021/12/16
DIMETHISTERONE Chemical Properties,Usage,Production
Originator
Oracon,Mead Johnson,US,1965
Uses
Dimethisterone-d3 is the labeled analogue of Dimethisterone (D460430), an oral contraceptive steroid.
Definition
ChEBI: Dimethisterone is a 3-hydroxy steroid. It has a role as an androgen.
Manufacturing Process
A solution of a Grignard reagent, employing 1-propyne (8 grams) was prepared. To this reagent there was added the 3,3 ethylenedioxy derivative (4 grams) of 6-α-methylandrost-4-ene-3,17-dione in tetrahydrofuran (100 ml), and the mixture heated under reflux for 3 hours. After decomposition of the complex with aqueous ammonium chloride, the product was isolated with ether and treated with 90% acetic acid (50 ml) for 30 minutes at 100°C. The product obtained by pouring the mixture into water and extracting with ether was crystallized from aqueous methanol. 17β-Hydroxy-6α-methyl-17α-(prop- 1-ynyl)androst-4-en-3-one formed plates MP 99° to 102°C.
Therapeutic Function
Progestin
DIMETHISTERONE Preparation Products And Raw materials
Raw materials
Preparation Products
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