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3-Nitro-L-tyrosine

Product Name
3-Nitro-L-tyrosine
CAS No.
621-44-3
Chemical Name
3-Nitro-L-tyrosine
Synonyms
3-NITRO-TYROSINE;NITROTYROSINE;H-TYR(3-NO2)-OH;Tyr(3'-NO2);Z-D-Dap(Boc);H-TYR(M-NO2)-OH;m-Nitro-L-Tyr-OH;H-3-NITRO-TYR-OH;H-M-NITRO-TYR-OH;M-NITRO-L-TYROSINE
CBNumber
CB8703176
Molecular Formula
C9H10N2O5
Formula Weight
226.19
MOL File
621-44-3.mol
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3-Nitro-L-tyrosine Property

Melting point:
233-235 °C (dec.) (lit.)
alpha 
4 º (c=1, 1N HCl)
Boiling point:
367.79°C (rough estimate)
Density 
1.4160 (rough estimate)
refractive index 
1.5373 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
Aqueous Acid (Slightly), Water
pka
2.17±0.20(Predicted)
form 
crystalline
color 
yellow to green
Water Solubility 
insoluble
BRN 
2813157
CAS DataBase Reference
621-44-3(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
24/25-37/39-26-36
WGK Germany 
3
HS Code 
29225090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
N7389
Product name
3-Nitro-L-tyrosine
Purity
crystalline
Packaging
5g
Price
$125
Updated
2024/03/01
Sigma-Aldrich
Product number
N7389
Product name
3-Nitro-L-tyrosine
Purity
crystalline
Packaging
10g
Price
$236
Updated
2024/03/01
TCI Chemical
Product number
N0905
Product name
3-Nitro-L-tyrosine
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$183
Updated
2024/03/01
TCI Chemical
Product number
N0905
Product name
3-Nitro-L-tyrosine
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$656
Updated
2024/03/01
Alfa Aesar
Product number
A11018
Product name
3-Nitro-L-tyrosine, 98%
Packaging
5g
Price
$44.8
Updated
2023/06/20
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3-Nitro-L-tyrosine Chemical Properties,Usage,Production

Description

Nitrotyrosine is formed by peroxynitrite-mediated nitration of protein tyrosine residues. Its presence on proteins can be used as a marker for peroxynitrite formation in vivo. Both free and protein-bound nitrotyrosine are commonly found in mammalian tissues and are increased in pathological conditions. The basal levels of free nitrotyrosine in human plasma is approximately 3 nM as determined by gas chromatography/mass spectrometry.

Chemical Properties

ochre-yellow to yellow-green powder

Uses

A marker for peroxynitrite. Oxidant and cytotoxic agent.

Uses

3-Nitro-L-tyrosine is used as an indicator of the formation of peroxynitrite by NO-dependent oxidative damage.

Definition

ChEBI: 3-nitro-L-tyrosine is a 3-nitrotyrosine comprising L-tyrosine having a nitro group at the 3-position on the phenyl ring. It is a L-tyrosine derivative, a non-proteinogenic L-alpha-amino acid and a 3-nitrotyrosine. It is an enantiomer of a 3-nitro-D-tyrosine.

Biochem/physiol Actions

Oxidant and cytotoxic agent.

3-Nitro-L-tyrosine Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Nitro-L-tyrosine Suppliers

Wuxi maimo topp biotechnology co., LTD
Tel
13771048682
Email
alice@mimotopes.cn
Country
China
ProdList
5835
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
GL Biochem (Shanghai) Ltd
Tel
21-61263452 13641803416
Fax
86-21-61263399
Email
ymbetter@glbiochem.com
Country
China
ProdList
9981
Advantage
64
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18738
Advantage
57

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