ChemicalBook > CAS DataBase List > Vanillyl alcohol

Vanillyl alcohol

Product Name
Vanillyl alcohol
CAS No.
498-00-0
Chemical Name
Vanillyl alcohol
Synonyms
4-HYDROXY-3-METHOXYBENZYL ALCOHOL;Vanillin alcohol;Vanillinol;VANILLYL ALCOHOL(RG);4-Hydroxy-3-Methoxybenze-neMenthanol;4-HYDROXY-3-METHOXYBENZYL ALCOHOL (VANILLYL ALCOHOL);NSC 3993;vanillol;Vanillyl;FEMA 3737
CBNumber
CB8709532
Molecular Formula
C8H10O3
Formula Weight
154.16
MOL File
498-00-0.mol
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Vanillyl alcohol Property

Melting point:
110-117 °C (lit.)
Boiling point:
237.52°C (rough estimate)
Density 
1.1690 (rough estimate)
refractive index 
1.4620 (estimate)
FEMA 
3737 | VANILLYL ALCOHOL
storage temp. 
Inert atmosphere,Room Temperature
solubility 
soluble in Methanol
form 
Fine Crystalline Powder
pka
9.75±0.18(Predicted)
color 
Off-white to beige
Odor
at 100.00 %. sweet creamy vanilla caramellic coconut graham cracker tonka milky powdery
Odor Type
creamy
Water Solubility 
Soluble in 95% ethanol (5 %), water, and oils.
JECFA Number
886
BRN 
1910044
Stability:
Stable. Incompatible with strong oxidizing agents, strong acids.
LogP
0.42
CAS DataBase Reference
498-00-0(CAS DataBase Reference)
NIST Chemistry Reference
4-Hydroxy-3-methoxybenzyl alcohol(498-00-0)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
Hazard Note 
Irritant
HS Code 
29095090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
W373702
Product name
Vanillyl alcohol
Purity
≥98%, FG
Packaging
100g
Price
$115
Updated
2024/03/01
Sigma-Aldrich
Product number
W373702
Product name
Vanillyl alcohol
Purity
≥98%, FG
Packaging
1kg
Price
$386
Updated
2024/03/01
Sigma-Aldrich
Product number
175536
Product name
4-Hydroxy-3-methoxybenzyl alcohol
Purity
98%
Packaging
50g
Price
$66.8
Updated
2024/03/01
Sigma-Aldrich
Product number
175536
Product name
4-Hydroxy-3-methoxybenzyl alcohol
Purity
98%
Packaging
250g
Price
$145
Updated
2024/03/01
TCI Chemical
Product number
V0018
Product name
Vanillyl Alcohol
Purity
>98.0%(GC)
Packaging
25g
Price
$63
Updated
2024/03/01
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Vanillyl alcohol Chemical Properties,Usage,Production

Description

4-hydroxy-3-methoxybenzyl alcohol (also known as vanillyl alcohol) is often used as a deodorant component that is active in preventing the formation of body odor. It can also be used as a flavoring agent. Recent studies have also demonstrated that it has certain pharmacological effects. For example, it has been confirmed that it has certain neuro-protective effects through suppressing the oxidative stress and anti-apoptotic activity in toxin-induced dopaminergic MN9D cells, making it a potential candidate for the treatment of neurodegenerative diseases such as Parkinson’s disease.

Chemical Properties

Vanillyl alcohol is a lignin derived aromatic diol. It has a mild, sweet, balsamic, vanilla-like odor.  It has a potential for the production of renewable epoxy thermosets. A bio-based bisphenolic analogue, bisguaiacol, was synthesized via the electrophilic aromatic condensation of vanillyl alcohol and guaiacol. From this, the diglycidyl ether of bisguaiacol was prepared. Further, three single aromatic diglycidyl ethers were synthesized from vanillyl alcohol, gastrodigenin, and hydroquinone. 

Chemical Properties

crystalline white to off-white powder

Uses

Used as a flavoring agent. Other possible uses, vanilla, coconut, cream and other dairy nuances, coumarin.

Definition

ChEBI: Vanillyl alcohol is a monomethoxybenzene that is 2-methoxyphenol substituted by a hydroxymethyl group at position 4. It has a role as a plant metabolite. It is a member of guaiacols and a member of benzyl alcohols.

Taste threshold values

Sweet, creamy and milky with a slightly powdery mouthfeel.

General Description

Vanillyl alcohol belongs to the phenolic group of compounds which are widely used as oxidants in food products.

Biochem/physiol Actions

Odor at 1.0%: sweet creamy, phenolic, vanilla and coconut-like with slight brown and coumarinic nuances.

Synthesis

Vanillyl alcohol is prepared from Vanillin by hydrogenation in presence of Platinum black.

References

Brune, I, et al. "Under the influence of the active deodorant ingredient 4-hydroxy-3-methoxybenzyl alcohol, the skin bacterium Corynebacterium jeikeium moderately responds with differential gene expression." Journal of Biotechnology 127.1(2006):21-33.
Hsu, Lun Chung, Z. H. Wen, and K. Y. Lee. "Use of vanillyl alcohol for the treatment of Parkinson's disease." (2009).
Kim, I. S., D. K. Choi, and H. J. Jung. "Neuroprotective effects of vanillyl alcohol in Gastrodia elata Blume through suppression of oxidative stress and anti-apoptotic activity in toxin-induced dopaminergic MN9D cells." Molecules 16.7(2011):5349.

Vanillyl alcohol Preparation Products And Raw materials

Raw materials

Preparation Products

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Vanillyl alcohol Suppliers

Wuhan Qiaofeng Chemical Technology Co., Ltd.
Tel
18271818137
Email
2814999308@qq.com
Country
China
ProdList
298
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
Advantage
66
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
8415
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12438
Advantage
60
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
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View Lastest Price from Vanillyl alcohol manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
Vanillyl alcohol 498-00-0
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-25
Hebei Yanxi Chemical Co., Ltd.
Product
Vanillyl alcohol 498-00-0
Price
US $10.00-1.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20 tons
Release date
2023-09-28
Hebei Chuanghai Biotechnology Co,.LTD
Product
4-Hydroxy-3-Methoxybenzyl Alcohol 498-00-0
Price
US $3.00/KG
Min. Order
1KG
Purity
99.%
Supply Ability
50 ton
Release date
2024-08-23

498-00-0, Vanillyl alcoholRelated Search:


  • 3,4-Dihydroxybenzyl alcohol 3-Methyl ester
  • 4-Hydroxy-3-Methoxybenze-neMenthanol
  • Vanillinol
  • α,4-Dihydroxy-3-Methoxytoluene
  • 2-Hydroxy-5-(hydroxymethyl)anisole, 4-Hydroxy-3-methoxybenzyl alcohol, Vanillyl alcohol
  • 4-Hydroxy-3-Methoxybenzyl alcohol, 99% 50GR
  • 3-Methoxy-4-hydroxybenzyl alcohol
  • Vanillic alcohol
  • Vanillin alcohol
  • 4-HYDROXY-3-METHOXYBENZYL ALCOHOL, 98+%
  • 4-HYDROXY-3-METHOXYBENZYL ALCOHOL (VANILLYL ALCOHOL)
  • 4-Hydroxy-3-methoxybenzyl alcohol,99%
  • VANILLYL ALCOHOL(RG)
  • Hydroxy-3-Methoxybenzyl alc
  • 4-Hydroxy-3-Methoxybenzyl alcohol 98%
  • NSC 3993
  • Vanillin Impurity 3
  • 4-HYDROXY-3-METHOXYBENZYL ALCOHOL
  • 4-hydroxy-3-methoxy-benzenemethano
  • 4-hydroxy-3-methoxybenzyl
  • 4-hydroxy-3-methoxybenzylalcohol(vanillicalcohol)
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  • Vanillyl alcohol (4-Hydroxy-3-methoxybenzyl alcohol)
  • Vanillyl
  • FEMA 3737
  • A 4-DIHYDROXY-3-METHOXYTOLUENE
  • CITRONELLOL, D-(SG)
  • HOMOVANILLICALCOHOL
  • 4-HYDROXY-3-METHOXYBENZENEMETHANOL
  • 4-HYDROXYMETHYL-2-METHOXY-PHENOL
  • 4-Hydroxy-3-methoxybenzyl alcohol USP/EP/BP
  • para-vanillyl alcohol
  • 4-Hydroxy-3-Methoxybenzyl Alcohol CAS 498-00-0 C8h10o3
  • TIANFU-CHEM 498-00-0 4-Hydroxy-3-methoxybenzyl alcohol
  • HEXADECYL 2-ETHYLHEXANOATE 59130-69-7
  • Vanillyl alcohol (6CI, 8CI)
  • Vanillyl Alcohol, ≥ 98.0%
  • 498-00-0
  • 4980-00-0
  • HOC6H3CH2OHOCH3
  • HOC6H3OCH3CH2OH
  • CH3OC6H3OHCH2OH
  • ALCOHOL
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