ChemicalBook > CAS DataBase List > 3,5-DIMETHYLISOXAZOLE-4-CARBOXYLIC ACID

3,5-DIMETHYLISOXAZOLE-4-CARBOXYLIC ACID

Product Name
3,5-DIMETHYLISOXAZOLE-4-CARBOXYLIC ACID
CAS No.
2510-36-3
Chemical Name
3,5-DIMETHYLISOXAZOLE-4-CARBOXYLIC ACID
Synonyms
AKOS PAO-1555;BUTTPARK 27\08-43;RARECHEM AL BO 0995;TIMTEC-BB SBB004158;3,5-dimethyl-4-isoxazolecarboxylate;diMethyl-1,2-oxazole-4-carboxylic acid;3,5-DIMETHYLISOXASOLE-4-CARBOXYLIC ACID;3,5-DIMETHYLISOXAZOLE-4-CARBOXYLIC ACID;3,5-DIMETHYL-4-ISOXAZOLECARBOXYLIC ACID;4-Isoxazolecarboxylic acid, 3,5-dimethyl-
CBNumber
CB8710204
Molecular Formula
C6H7NO3
Formula Weight
141.12
MOL File
2510-36-3.mol
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3,5-DIMETHYLISOXAZOLE-4-CARBOXYLIC ACID Property

Melting point:
141-145 °C(lit.)
Boiling point:
258.14°C (rough estimate)
Density 
1.3710 (rough estimate)
refractive index 
1.4890 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
soluble in Methanol
form 
powder to crystal
pka
2.53±0.32(Predicted)
color 
White to Almost white
BRN 
115819
CAS DataBase Reference
2510-36-3(CAS DataBase Reference)
NIST Chemistry Reference
3,5-Dimethylisoxazole-4-carboxylic acid(2510-36-3)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
20/21/22
Safety Statements 
24/25-36-22
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29349990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
637653
Product name
3,5-Dimethylisoxazole-4-carboxylic acid
Purity
98%
Packaging
5g
Price
$104
Updated
2022/05/15
TCI Chemical
Product number
D4603
Product name
3,5-Dimethylisoxazole-4-carboxylic Acid
Purity
>98.0%(HPLC)(T)
Packaging
1g
Price
$59
Updated
2025/07/31
TCI Chemical
Product number
D4603
Product name
3,5-Dimethylisoxazole-4-carboxylic Acid
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$205
Updated
2025/07/31
Biosynth Carbosynth
Product number
FD112178
Product name
3,5-Dimethylisoxazole-4-carboxylic acid
Packaging
250g
Price
$875
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
JK103771
Product name
3,5-Dimethylisoxazole-4-carboxylic Acid
Purity
98%
Packaging
5g
Price
$108
Updated
2021/12/16
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3,5-DIMETHYLISOXAZOLE-4-CARBOXYLIC ACID Chemical Properties,Usage,Production

Chemical Properties

light beige powder

Synthesis

17147-42-1

2510-36-3

General procedure for the synthesis of 3,5-dimethylisoxazole-4-carboxylic acid from ethyl 3,5-dimethylisoxazole-4-carboxylate: to a mixture of ethyl 3,5-dimethyl-4-isoxazolecarboxylate (2.4 g, 14 mmol) in a solution of tetrahydrofuran (THF, 8 mL) and methanol (MeOH, 8 mL), an aqueous solution of 5 N sodium hydroxide (NaOH) (8.5 mL ). The reaction mixture was stirred at room temperature for 8 hours. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure, followed by acidification with 6 N aqueous hydrochloric acid (HCl) to pH = 2. The precipitated white solid product was filtered, washed with water, and dried to afford 3,5-dimethylisoxazole-4-carboxylic acid (2.1 g, 94.0% yield). The structure of the product was confirmed by 1H NMR (300 MHz, CDCl3): δ 2.72 (s, 3H), 2.49 (s, 3H).

References

[1] Bioorganic and Medicinal Chemistry Letters, 2018, vol. 28, # 17, p. 2879 - 2884
[2] Justus Liebigs Annalen der Chemie, 1893, vol. 277, p. 174
[3] Journal of the American Chemical Society, 1967, vol. 89, p. 5461 - 5462

3,5-DIMETHYLISOXAZOLE-4-CARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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3,5-DIMETHYLISOXAZOLE-4-CARBOXYLIC ACID Suppliers

J & K SCIENTIFIC LTD.
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18210857532; 18210857532
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86-10-82849933
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jkinfo@jkchemical.com
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China
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Meryer (Shanghai) Chemical Technology Co., Ltd.
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4006356688 18621169109
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86-21-61259102
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China
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400-0066400 13621662912
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New Energy Chemicals
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Sales-CN@TCIchemicals.com
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Jia Xing Isenchem Co.,Ltd
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View Lastest Price from 3,5-DIMETHYLISOXAZOLE-4-CARBOXYLIC ACID manufacturers

Career Henan Chemical Co
Product
3,5-DIMETHYLISOXAZOLE-4-CARBOXYLIC ACID 2510-36-3
Price
US $1.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
100KG
Release date
2018-12-22
Career Henan Chemical Co
Product
3,5-DIMETHYLISOXAZOLE-4-CARBOXYLIC ACID 2510-36-3
Price
US $8.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10tons
Release date
2018-12-23

2510-36-3, 3,5-DIMETHYLISOXAZOLE-4-CARBOXYLIC ACIDRelated Search:


  • AKOS PAO-1555
  • BUTTPARK 27\08-43
  • 3,5-DIMETHYLISOXAZOLE-4-CARBOXYLIC ACID, PURISS, 98%
  • 3,5-Dimethylisoxazole-4-carboxylic acid ,98%
  • 3,5- two Methylisoxazole-4- carboxylic acid
  • 3,5-Dimethylisoxazole-4-carboxylicacid,99%
  • diMethyl-1,2-oxazole-4-carboxylic acid
  • 3,5-DIMETHYL-4-ISOXAZOLECARBOXYLIC ACID
  • 3,5-DIMETHYLISOXAZOLE-4-CARBOXYLIC ACID
  • 3,5-DIMETHYLISOXASOLE-4-CARBOXYLIC ACID
  • 4-Isoxazolecarboxylic acid, 3,5-dimethyl-
  • RARECHEM AL BO 0995
  • TIMTEC-BB SBB004158
  • 3,5-dimethyl-4-isoxazolecarboxylate
  • 2510-36-3
  • C6H7NO3
  • C6H6NO3
  • Carboxylic acid
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  • Chemical Synthesis
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  • Oxazole&Isoxazole
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