3,5-DIMETHYLISOXAZOLE-4-CARBOXYLIC ACID
- Product Name
- 3,5-DIMETHYLISOXAZOLE-4-CARBOXYLIC ACID
- CAS No.
- 2510-36-3
- Chemical Name
- 3,5-DIMETHYLISOXAZOLE-4-CARBOXYLIC ACID
- Synonyms
- AKOS PAO-1555;BUTTPARK 27\08-43;RARECHEM AL BO 0995;TIMTEC-BB SBB004158;3,5-dimethyl-4-isoxazolecarboxylate;diMethyl-1,2-oxazole-4-carboxylic acid;3,5-DIMETHYLISOXASOLE-4-CARBOXYLIC ACID;3,5-DIMETHYLISOXAZOLE-4-CARBOXYLIC ACID;3,5-DIMETHYL-4-ISOXAZOLECARBOXYLIC ACID;4-Isoxazolecarboxylic acid, 3,5-dimethyl-
- CBNumber
- CB8710204
- Molecular Formula
- C6H7NO3
- Formula Weight
- 141.12
- MOL File
- 2510-36-3.mol
3,5-DIMETHYLISOXAZOLE-4-CARBOXYLIC ACID Property
- Melting point:
- 141-145 °C(lit.)
- Boiling point:
- 258.14°C (rough estimate)
- Density
- 1.3710 (rough estimate)
- refractive index
- 1.4890 (estimate)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- soluble in Methanol
- form
- powder to crystal
- pka
- 2.53±0.32(Predicted)
- color
- White to Almost white
- BRN
- 115819
- CAS DataBase Reference
- 2510-36-3(CAS DataBase Reference)
- NIST Chemistry Reference
- 3,5-Dimethylisoxazole-4-carboxylic acid(2510-36-3)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 20/21/22
- Safety Statements
- 24/25-36-22
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 29349990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- 637653
- Product name
- 3,5-Dimethylisoxazole-4-carboxylic acid
- Purity
- 98%
- Packaging
- 5g
- Price
- $104
- Updated
- 2022/05/15
- Product number
- D4603
- Product name
- 3,5-Dimethylisoxazole-4-carboxylic Acid
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 1g
- Price
- $59
- Updated
- 2025/07/31
- Product number
- D4603
- Product name
- 3,5-Dimethylisoxazole-4-carboxylic Acid
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 5g
- Price
- $205
- Updated
- 2025/07/31
- Product number
- FD112178
- Product name
- 3,5-Dimethylisoxazole-4-carboxylic acid
- Packaging
- 250g
- Price
- $875
- Updated
- 2021/12/16
- Product number
- JK103771
- Product name
- 3,5-Dimethylisoxazole-4-carboxylic Acid
- Purity
- 98%
- Packaging
- 5g
- Price
- $108
- Updated
- 2021/12/16
3,5-DIMETHYLISOXAZOLE-4-CARBOXYLIC ACID Chemical Properties,Usage,Production
Chemical Properties
light beige powder
Synthesis
17147-42-1
2510-36-3
General procedure for the synthesis of 3,5-dimethylisoxazole-4-carboxylic acid from ethyl 3,5-dimethylisoxazole-4-carboxylate: to a mixture of ethyl 3,5-dimethyl-4-isoxazolecarboxylate (2.4 g, 14 mmol) in a solution of tetrahydrofuran (THF, 8 mL) and methanol (MeOH, 8 mL), an aqueous solution of 5 N sodium hydroxide (NaOH) (8.5 mL ). The reaction mixture was stirred at room temperature for 8 hours. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure, followed by acidification with 6 N aqueous hydrochloric acid (HCl) to pH = 2. The precipitated white solid product was filtered, washed with water, and dried to afford 3,5-dimethylisoxazole-4-carboxylic acid (2.1 g, 94.0% yield). The structure of the product was confirmed by 1H NMR (300 MHz, CDCl3): δ 2.72 (s, 3H), 2.49 (s, 3H).
References
[1] Bioorganic and Medicinal Chemistry Letters, 2018, vol. 28, # 17, p. 2879 - 2884
[2] Justus Liebigs Annalen der Chemie, 1893, vol. 277, p. 174
[3] Journal of the American Chemical Society, 1967, vol. 89, p. 5461 - 5462
3,5-DIMETHYLISOXAZOLE-4-CARBOXYLIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3,5-DIMETHYLISOXAZOLE-4-CARBOXYLIC ACID manufacturers
- Product
- 3,5-DIMETHYLISOXAZOLE-4-CARBOXYLIC ACID 2510-36-3
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2018-12-22
- Product
- 3,5-DIMETHYLISOXAZOLE-4-CARBOXYLIC ACID 2510-36-3
- Price
- US $8.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10tons
- Release date
- 2018-12-23