2-Nitro-N-hydroxyethyl aniline

Product Name: 2-Nitro-N-hydroxyethyl aniline
CAS No.: 4926-55-0
Chemical Name: 2-Nitro-N-hydroxyethyl aniline
Synonyms: HC YELLOW 2;hc-yelow 2;HC YELLOW NO 2;JAROCOL YELLOW 2;2-Nitro-N-hydroxyeth;Nitroanilino)Ethanol;Adrenaline Impurity 103;2-(2-Nitroanilino)Ethanol;ethanol, 2-(o-nitroanilino)-;N-Hydroxyethyl-2-nitroaniline
CBNumber: CB8715911
Molecular Formula: C8H10N2O3
Formula Weight: 182.18
MOL File: 4926-55-0.mol

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2-Nitro-N-hydroxyethyl aniline Property

Melting point:: 71-73°C
Boiling point:: 376.6±22.0 °C(Predicted)
Density: 1.352±0.06 g/cm3(Predicted)
vapor pressure: 0Pa at 20℃
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Solid
pka: 14.60±0.10(Predicted)
color: Dark Orange to Red
Water Solubility: 1.85g/L at 20℃
λmax: 441nm(NaOH aq.)(lit.)
InChI: InChI=1S/C8H10N2O3/c11-6-5-9-7-3-1-2-4-8(7)10(12)13/h1-4,9,11H,5-6H2
InChIKey: LFOUYKNCQNVIGI-UHFFFAOYSA-N
SMILES: C(O)CNC1=CC=CC=C1[N+]([O-])=O
LogP: 1.5 at 20℃
CAS DataBase Reference: 4926-55-0(CAS DataBase Reference)
EPA Substance Registry System: Ethanol, 2-[(2-nitrophenyl)amino]- (4926-55-0)

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Safety

Hazard Codes: Xi
Hazard Note: Irritant
HS Code: 2922290090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TCI Chemical

Product number: N1000
Product name: 2-(2-Nitroanilino)ethanol
Purity: >98.0%(GC)
Packaging: 5g
Price: $89
Updated: 2025/07/31

TCI Chemical

Product number: N1000
Product name: 2-(2-Nitroanilino)ethanol
Purity: >98.0%(GC)
Packaging: 25g
Price: $267
Updated: 2025/07/31

TRC

Product number: N525160
Product name: 2-(2-Nitroanilino)ethanol
Packaging: 10g
Price: $60
Updated: 2021/12/16

AK Scientific

Product number: F750
Product name: 2-Nitro-N-(hydroxyethyl)aniline
Packaging: 100g
Price: $67
Updated: 2021/12/16

AK Scientific

Product number: F750
Product name: 2-Nitro-N-(hydroxyethyl)aniline
Packaging: 1kg
Price: $334
Updated: 2021/12/16

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2-Nitro-N-hydroxyethyl aniline Chemical Properties,Usage,Production

Chemical Properties

Orange crystal powder

Uses

2-(2-Nitroanilino)ethanol is used in the preparation of (phenylamino)quinoxalinone derivatives which has been identified as a new class of glycogen phosphorylase inhibitors.

Flammability and Explosibility

Not classified

Synthesis

141-43-5

88-73-3

4926-55-0

In a 1L three-necked flask, 100 g of o-chloronitrobenzene, 450 g of hexane and 10 g of sodium fluoride were added sequentially and the temperature was raised to 80 °C. 60g of ethanolamine was slowly added dropwise, and the reaction temperature was maintained at 80°C for 20 hours. Sampling and analysis were carried out during the reaction, monitored by HPLC, and the reaction was terminated when the content of o-chloronitrobenzene was less than 3%. Upon completion of the reaction, decompression distillation was carried out to remove the solvent and the distillation temperature was controlled at 90 °C. Subsequently, methanol and water were added for crystallization, and after filtration, washing and drying, 103 g of red crystalline powder N-(2-nitrophenyl)ethanolamine was obtained, with a purity of 99.6% by HPLC.

References

[1] Heterocycles, 1999, vol. 51, # 11, p. 2561 - 2573
[2] Journal of the American Chemical Society, 1939, vol. 61, p. 1321,1323,1324
[3] Helvetica Chimica Acta, 1936, vol. 19, p. 1029,1030, 1033
[4] Chemische Berichte, 1947, vol. 80, p. 263,270
[5] Patent: US2434564, 1943,

2-Nitro-N-hydroxyethyl aniline Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Nitro-N-hydroxyethyl aniline Suppliers

Americas 1 Belgium 1 China 171 Europe 3 Germany 3 India 3 Italy 1 Japan 4 Switzerland 1 The Netherlands 1 Ukraine 3 United Kingdom 7 United States 15 Global 214

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Maya High Purity Chemicals

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View Lastest Price from 2-Nitro-N-hydroxyethyl aniline manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 2-Nitro-N-hydroxyethyl aniline 4926-55-0
Price: US $1.00-2.10/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20000KG
Release date: 2024-08-09

Hangzhou ICH Biofarm Co., Ltd

Product: 2-Nitro-N-hydroxyethyl aniline 4926-55-0
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 98.0% GC
Supply Ability: 100kg
Release date: 2023-07-13

LY Global chemicals co.,ltd .

Product: 2-Nitro-N-hydroxyethyl aniline 4926-55-0
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%Min
Supply Ability: 1000kg
Release date: 2023-03-12

4926-55-0, 2-Nitro-N-hydroxyethyl anilineRelated Search:

2-(METHYLSULFONYL)ETHANOL Monoethanolamine Diethanolamine Ethyl acetate ALTRENOGEST Acid Blue 93 Glycine 3-Aminophenol PHOSPHATIDYLETHANOLAMINE Aniline 6-Aminocaproic acid 1-Phenyl-2-nitropropene Tris(hydroxymethyl)aminomethane NITROGEN DIOXIDE 2,4-DINITRO-N-(2-HYDROXYETHYL)ANILINE N-(2,4-DINITROPHENYL)-L-PHENYLALANINE N-(2,4-DINITROPHENYL)-L-SERINE 2-Dimethylaminoethanol

2-[(2-nitrophenyl)amino]-ethano

4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoro-2-iodo-1-undecanol

Ethanol,2-[(2-nitrophenyl)amino]-

N-(2-HYDROXYETHYL)-2-NITROANILINE

2-[(2-NITROPHENYL)AMINO]ETHANOL

2-NITRO-N-(HYDROXYETHYL)ANILINE

2-NITRO-N-(2-HYDROXYETHYL)ANILINE

HC YELLOW NO 2

hc-yelow 2

HC YELLOW 2

JAROCOL YELLOW 2

2-(2-Nitroanilino)Ethanol

N-Hydroxyethyl-2-nitroaniline

2-(2-NitroPhenylamine)Ethanol(HcYellow2)

N-(2-HYDROXYETHYL)-ORTHO-NITROANILINE

N-(2-Nitrophenyl)-ethanolamine

HC Yellow No.2 2-Nitro-N-(Hydroxyethyl)Aniline

2-Nitro-N-hydroxyeth

2-(2-nitrophenyl)aMinoethanol (HC Yellow No. 2)

2-((2-nitrophenyl)amino)ethan-1-ol

2-(2-Nitroanilino)ethanol &gt

2-Nitro-N-Hydroxyethyl Aniline,>98%

TIANFU-CHEM 2-Nitro-N-hydroxyethyl aniline

ethanol, 2-(o-nitroanilino)-

Nitroanilino)Ethanol

Adrenaline Impurity 103

4926-55-0

Electronic Chemicals

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