BIS(2,2,2-TRIFLUOROETHYL) ETHER
- Product Name
- BIS(2,2,2-TRIFLUOROETHYL) ETHER
- CAS No.
- 333-36-8
- Chemical Name
- BIS(2,2,2-TRIFLUOROETHYL) ETHER
- Synonyms
- HFE;SF6539;SKL232;Idoklon;skf6539;Flurotyl;Indiklon;Indoklon;SKF 6539;SK&F-6539
- CBNumber
- CB8723208
- Molecular Formula
- C4H4F6O
- Formula Weight
- 182.06
- MOL File
- 333-36-8.mol
BIS(2,2,2-TRIFLUOROETHYL) ETHER Property
- Melting point:
- 25°C
- Boiling point:
- 62-63 °C (lit.)
- Density
- 1.404 g/mL at 25 °C (lit.)
- refractive index
- n20/D 1.300(lit.)
- Flash point:
- 35 °F
- storage temp.
- Flammables area
- solubility
- DMSO : ≥ 125 mg/mL (686.59 mM)
- form
- clear liquid
- color
- Colorless to Almost colorless
- Specific Gravity
- 1.41
- Merck
- 14,4201
- BRN
- 1811927
- CAS DataBase Reference
- 333-36-8(CAS DataBase Reference)
- EPA Substance Registry System
- HFE-356mff2 (333-36-8)
Safety
- Hazard Codes
- F,Xi,T
- Risk Statements
- 11-36/37/38
- Safety Statements
- 16-26-36
- RIDADR
- UN 3271 3/PG 2
- WGK Germany
- 3
- RTECS
- KN3675000
- Hazard Note
- Flammable/Toxic/Convulsant
- HazardClass
- 3.1
- PackingGroup
- II
- HS Code
- 29091990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 287571
- Product name
- Bis(2,2,2-trifluoroethyl) ether
- Purity
- 98%
- Packaging
- 5g
- Price
- $113
- Updated
- 2024/03/01
- Product number
- B1293
- Product name
- Bis(2,2,2-trifluoroethyl) Ether
- Purity
- >99.0%(GC)
- Packaging
- 1g
- Price
- $59
- Updated
- 2024/03/01
- Product number
- B1293
- Product name
- Bis(2,2,2-trifluoroethyl) Ether
- Purity
- >99.0%(GC)
- Packaging
- 5g
- Price
- $163
- Updated
- 2024/03/01
- Product number
- B585665
- Product name
- Bis(2,2,2-trifluoroethyl) Ether
- Packaging
- 500mg
- Price
- $70
- Updated
- 2021/12/16
- Product number
- B585665
- Product name
- Bis(2,2,2-trifluoroethyl) Ether
- Packaging
- 1g
- Price
- $120
- Updated
- 2021/12/16
BIS(2,2,2-TRIFLUOROETHYL) ETHER Chemical Properties,Usage,Production
Chemical Properties
clear colorless liquid
Originator
Indoklon ,Ohio Medical, US ,1964
Uses
Bis(2,2,2-trifluoroethyl) ether was used to diminish self-discharge of Li-S cells having both low- and high-sulfur-loading sulfur cathodes.
Uses
Bis(2,2,2-trifluoroethyl) Ether is Prophylactic and/or therapeutic agent for Alzheimer''s disease.
Uses
5HT agonist
Definition
ChEBI: Flurotyl is an ether.
Manufacturing Process
23 parts of sodium metal were placed in 300 parts of dry dioxane in a reactor equipped with an agitator and reflux condenser. The dioxane was heated to reflux while stirring.150 parts of 2,2,2-trifluoroethanol were added very slowly in the period of about 1 hour, or until the sodium was all reacted, to form sodium 2,2,2-trifluoroethylate. 250 parts of 2,2,2-trifluoroethyl ptoluenesulfonate prepared by reacting 2,2,2-trifluoroethanol with p
Flurothyl toluenesulfonyl chloride were placed in another reactor and heated to about 160° to 185°C. The solution of sodium 2,2,2-trifluoroethylate in dioxane was added very slowly over a period of about 1? hours. Bis(2,2,2-trifluoroethyl) ether formed continuously and distilled from the reactor with the dioxane into a cooled receiving vessel. The condensed effluent from the reactor was fractionally distilled, yielding 46.5 parts of products boiling at 55° to 73°C.
The crude product was washed successively with concentrated HCl, 62% H2SO4,concentrated H2SO4 and 5% NaOH solution. It was dehydrated over a drying agent and then refractionated in a still. 20 parts of bis(2,2,2trifluoroethyl) ether were recovered (BP 62.5° to 63.5°C).
brand name
Indoklon (Ohmeda).
Therapeutic Function
Central stimulant, Convulsant
BIS(2,2,2-TRIFLUOROETHYL) ETHER Preparation Products And Raw materials
Raw materials
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View Lastest Price from BIS(2,2,2-TRIFLUOROETHYL) ETHER manufacturers
- Product
- Fluorothyl 333-36-8
- Price
- US $30.00-0.90/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-26
- Product
- BIS(2,2,2-TRIFLUOROETHYL) ETHER 333-36-8
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-08