BIS(2,2,2-TRIFLUOROETHYL) ETHER

Product Name: BIS(2,2,2-TRIFLUOROETHYL) ETHER
CAS No.: 333-36-8
Chemical Name: BIS(2,2,2-TRIFLUOROETHYL) ETHER
Synonyms: HFE;SF6539;SKL232;Idoklon;skf6539;Flurotyl;Indiklon;Indoklon;SKF 6539;SK&F-6539
CBNumber: CB8723208
Molecular Formula: C4H4F6O
Formula Weight: 182.06
MOL File: 333-36-8.mol

More

Less

BIS(2,2,2-TRIFLUOROETHYL) ETHER Property

Melting point:: 25°C
Boiling point:: 62-63 °C (lit.)
Density: 1.404 g/mL at 25 °C (lit.)
refractive index: n20/D 1.300(lit.)
Flash point:: 35 °F
storage temp.: Flammables area
solubility: DMSO : ≥ 125 mg/mL (686.59 mM)
form: clear liquid
color: Colorless to Almost colorless
Specific Gravity: 1.41
Merck: 14,4201
BRN: 1811927
CAS DataBase Reference: 333-36-8(CAS DataBase Reference)
EPA Substance Registry System: HFE-356mff2 (333-36-8)

More

Less

Safety

Hazard Codes: F,Xi,T
Risk Statements: 11-36/37/38
Safety Statements: 16-26-36
RIDADR: UN 3271 3/PG 2
WGK Germany: 3
RTECS: KN3675000
Hazard Note: Flammable/Toxic/Convulsant
HazardClass: 3.1
PackingGroup: II
HS Code: 29091990

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 287571
Product name: Bis(2,2,2-trifluoroethyl) ether
Purity: 98%
Packaging: 5g
Price: $113
Updated: 2024/03/01

TCI Chemical

Product number: B1293
Product name: Bis(2,2,2-trifluoroethyl) Ether
Purity: >99.0%(GC)
Packaging: 1g
Price: $59
Updated: 2024/03/01

TCI Chemical

Product number: B1293
Product name: Bis(2,2,2-trifluoroethyl) Ether
Purity: >99.0%(GC)
Packaging: 5g
Price: $163
Updated: 2024/03/01

TRC

Product number: B585665
Product name: Bis(2,2,2-trifluoroethyl) Ether
Packaging: 500mg
Price: $70
Updated: 2021/12/16

TRC

Product number: B585665
Product name: Bis(2,2,2-trifluoroethyl) Ether
Packaging: 1g
Price: $120
Updated: 2021/12/16

More

Less

BIS(2,2,2-TRIFLUOROETHYL) ETHER Chemical Properties,Usage,Production

Chemical Properties

clear colorless liquid

Originator

Indoklon ,Ohio Medical, US ,1964

Uses

Bis(2,2,2-trifluoroethyl) ether was used to diminish self-discharge of Li-S cells having both low- and high-sulfur-loading sulfur cathodes.

Uses

Bis(2,2,2-trifluoroethyl) Ether is Prophylactic and/or therapeutic agent for Alzheimer''s disease.

Uses

5HT agonist

Definition

ChEBI: Flurotyl is an ether.

Manufacturing Process

23 parts of sodium metal were placed in 300 parts of dry dioxane in a reactor equipped with an agitator and reflux condenser. The dioxane was heated to reflux while stirring.150 parts of 2,2,2-trifluoroethanol were added very slowly in the period of about 1 hour, or until the sodium was all reacted, to form sodium 2,2,2-trifluoroethylate. 250 parts of 2,2,2-trifluoroethyl ptoluenesulfonate prepared by reacting 2,2,2-trifluoroethanol with p Flurothyl toluenesulfonyl chloride were placed in another reactor and heated to about 160° to 185°C. The solution of sodium 2,2,2-trifluoroethylate in dioxane was added very slowly over a period of about 1? hours. Bis(2,2,2-trifluoroethyl) ether formed continuously and distilled from the reactor with the dioxane into a cooled receiving vessel. The condensed effluent from the reactor was fractionally distilled, yielding 46.5 parts of products boiling at 55° to 73°C.
The crude product was washed successively with concentrated HCl, 62% H2SO4,concentrated H2SO4 and 5% NaOH solution. It was dehydrated over a drying agent and then refractionated in a still. 20 parts of bis(2,2,2trifluoroethyl) ether were recovered (BP 62.5° to 63.5°C).

brand name

Indoklon (Ohmeda).

Therapeutic Function

Central stimulant, Convulsant

BIS(2,2,2-TRIFLUOROETHYL) ETHER Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

BIS(2,2,2-TRIFLUOROETHYL) ETHER Suppliers

Americas 1 Belgium 1 China 64 Europe 1 France 1 Germany 2 India 2 Japan 4 Russia 1 Switzerland 2 United Kingdom 11 United States 21 Global 111

TOKYO CHEMICAL INDUSTRY CO., LTD.

Tel: 03-36680489
Fax: 03-3668-0520
Email: Sales-JP@TCIchemicals.com
Country: Japan
ProdList: 28387
Advantage: 80

Daikin Chemicals Sales, Ltd.

Tel: --
Fax: --
Country: Japan
ProdList: 300
Advantage: 55

Shigematsu & Co., Ltd

Tel: --
Fax: --
Email: info@shigematsu-bio.com
Country: Japan
ProdList: 1066
Advantage: 64

Kanto Chemical Co., Inc.

Tel: --
Fax: --
Email: reag-info@gms.kanto.co.jp
Country: Japan
ProdList: 6756
Advantage: 74

More

Less

View Lastest Price from BIS(2,2,2-TRIFLUOROETHYL) ETHER manufacturers

Henan Fengda Chemical Co., Ltd

Product: Fluorothyl 333-36-8
Price: US $30.00-0.90/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-26

Henan Aochuang Chemical Co.,Ltd.

Product: BIS(2,2,2-TRIFLUOROETHYL) ETHER 333-36-8
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-08

333-36-8, BIS(2,2,2-TRIFLUOROETHYL) ETHERRelated Search:

2,2,2-TRIFLUOROETHYL TRIFLUOROACETATE BIS(2,2,2-TRIFLUOROETHYL) ETHER Trifluoroacetic anhydride 2,2,2-TRIFLUOROETHYL TRICHLOROMETHANESULFONATE 6-METHYL-2,4,6-TRIS(TRIFLUOROMETHYL)TETRAHYDROPYRAN-2,4-DIOL 2-METHYL-2,4,6-TRIS(TRIFLUOROMETHYL)-2H-PYRAN PENTAFLUOROETHYL 2,2,2-TRIFLUOROETHYL ETHER MALEIC ACID BIS(2,2,2-TRIFLUOROETHYL)ETHER MALEIC ACID BIS(2,2,2-TRIFLUOROETHYL)ETHER 1,1,1,3,3,3-Hexafluoroisopropyl trifluoroacetate PERFLUORO-T-BUTYL TRIFLUOROACETATE PERFLUORODIETHYL ETHER 2,2,X-TRIS(TRIFLUOROMETHYL)TRIFLUOROOXETANE 2-METHOXY-5-TETRADECYL-2,6-BIS-TRIFLUOROMETHYL-2,3-DIHYDRO-[1,3]OXAZIN-4-ONE 1-(DIETHOXYPHOSPHORYL)-2,2,2-TRIFLUOROETHYL TRIFLUOROACETATE PERFLUORO[2,5-DIMETHYL-2-(FLUOROCARBONYL)-4-OXO-1,3-DIOXOLANE] 6,7-BIS(DIMETHYLAMINO)-1,3-BIS(TRIFLUOROMETHYL)-1H,3H-BENZO[DE]ISOCHROMENE-1,3-DIOL 2,6-BIS(TRIFLUOROMETHYL)PYRAN-4-ONE

Di(2,2,2-trifluroethyl)ether

Bis(2,2,2-trifluoroethyl) ether 99%

Bis(2,2,2-trifluoroethyl)ether99%

2,2,2-TRIFLUOROETHYL ETHER 99%

2,2,2-Trifluoroethyl ether, Flurothyl

1,1'-Oxybis(2,2,2-trifluoroethane)

2,2,2-Trifluoroethyl ether,99%

1,1,1-Trifluoro-2-(2,2,2-trifluoroethoxy)ethane

2-(2,2,2-Trifluoroethoxy)-1,1,1-trifluoroethane

Bis(trifluoroethyl)ether

Ethane, 1,1'-oxybis[2,2,2-trifluoro-

Ether, bis(2,2,2-trifluoroethyl)

ether,bis(2,2,2-trifluoroethyl)

Fluoroethyl

Fluorothyl

Flurotyl

Hexafluorodiethyl ether

hexafluorodiethylether

HFE

Idoklon

Indiklon

Indoklon

SF6539

SK&F-6539

SKF 6539

skf6539

2,2,2-TRIFLUOROETHYL ETHER

BIS(2,2,2-TRIFLUOROETHYL) ETHER

DI(2,2,2-TRIFLUOROETHYL)ETHER

FLUROTHYL

2-trifluoroethyl) ether

Bis(2,2,2-trifluoroethyl) Ether &gt

2,2,2-Trifluorodiethyl ether

SKL232

inhibit,Fluorothyl,Inhibitor

333-36-8

CF3CH22O

Building Blocks

Oxygen Compounds

Organic Building Blocks

Ethers

IMITREX