4-chloro-6,7-dimethoxyquinoline
- Product Name
- 4-chloro-6,7-dimethoxyquinoline
- CAS No.
- 35654-56-9
- Chemical Name
- 4-chloro-6,7-dimethoxyquinoline
- Synonyms
- 4-Chloro-6,7-dimethoxyquioline;4-CHLORO-6;7-DIMETHOXYQUINOLINE;oro-6,7-dimethoxyquinoL;Cabozantinib Impurity 71;Cabozantinib Chloro Analog;4-CHLORO-6,7-DIMETHOXYQUINOLINE;6,7-DIMETHOXY-4-CHLOROQUINOLINE;4-Chloro-6,7-dimethoxy-quinolin;Quinoline, 4-chloro-6,7-dimethoxy-
- CBNumber
- CB8725015
- Molecular Formula
- C11H10ClNO2
- Formula Weight
- 223.66
- MOL File
- 35654-56-9.mol
4-chloro-6,7-dimethoxyquinoline Property
- Melting point:
- 132.0 to 136.0 °C
- Boiling point:
- 325.2±37.0 °C(Predicted)
- Density
- 1.265±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 3.95±0.30(Predicted)
- color
- Pale Brown to Light Brown
- InChI
- InChI=1S/C11H10ClNO2/c1-14-10-5-7-8(12)3-4-13-9(7)6-11(10)15-2/h3-6H,1-2H3
- InChIKey
- WRVHQEYBCDPZEU-UHFFFAOYSA-N
- SMILES
- N1C2C(=CC(OC)=C(OC)C=2)C(Cl)=CC=1
- CAS DataBase Reference
- 35654-56-9(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- CDS007782
- Product name
- 4-chloro-6,7-dimethoxyquinoline
- Purity
- AldrichCPR
- Packaging
- 250mg
- Price
- $104
- Updated
- 2024/03/01
- Product number
- C2938
- Product name
- 4-Chloro-6,7-dimethoxyquinoline
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $94
- Updated
- 2024/03/01
- Product number
- C2938
- Product name
- 4-Chloro-6,7-dimethoxyquinoline
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $376
- Updated
- 2024/03/01
- Product number
- C365930
- Product name
- 4-Chloro-6,7-dimethoxyquinoline
- Packaging
- 1g
- Price
- $220
- Updated
- 2021/12/16
- Product number
- CS-D1175
- Product name
- 4-Chloro-6,7-dimethoxyquinoline
- Purity
- 99.65%
- Packaging
- 100g
- Price
- $228
- Updated
- 2021/12/16
4-chloro-6,7-dimethoxyquinoline Chemical Properties,Usage,Production
Chemical Properties
Light brown powder
Uses
4-Chloro-6,7-dimethoxyquinoline, can be used as an intermediate for the synthesis of various pharmaceutical and biologically active compounds. It is used for the preparation of Tivozanib (T447205), and Cabozantinib (C051500), acting as anticancer agents.
Application
4-chloro-6,7-dimethoxy-quinoline can be rich for Buddhist nun with for Wo Zhani medicine as preparing antitumor drug card The key intermediate of thing molecule synthesis.
Synthesis
With 3,4-dimethoxyaniline is raw material, obtains aniline compound through nitrification, iron powder reducing, then with Ethyl chloroformate, in Feldalat NM condition cyclization, prepares 4-hydroxyquinoline compounds, after through three Chlorethoxyfos chloro obtains 4-chloro-6,7-dimethoxy-quinoline.
4-chloro-6,7-dimethoxyquinoline Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-chloro-6,7-dimethoxyquinoline manufacturers
- Product
- 6,7-dimethoxy-4-chloroquinoline 35654-56-9
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1 ton
- Release date
- 2023-12-26
- Product
- 4-Chloro-6,7-dimethoxyquinoline 35654-56-9
- Price
- US $2.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50000tons
- Release date
- 2023-05-24
- Product
- 4-Chloro-6,7-dimethoxyquinoline 35654-56-9
- Price
- US $200.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%, 99.5% Sublimated
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-30