ChemicalBook > CAS DataBase List > 2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile

2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile

Product Name
2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile
CAS No.
58632-95-4
Chemical Name
2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile
Synonyms
BOC-ON;2-(BOC-OXYIMINO)-2-PHENYLACETONITRILE;Boc-On99%;Boc-ON, 98+%;BOC-ON, 99% 5GR;BOC-ON, 99% 25GR;2-(tert-Butoxycarbon;LABOTEST-BB LT00159655;2-(Boc-oxyimino)-2-phenylacetonitrile 99%;tert-butyl alpha-cyanobenzylaminyl carbonate
CBNumber
CB8741235
Molecular Formula
C13H14N2O3
Formula Weight
246.26
MOL File
58632-95-4.mol
More
Less

2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile Property

Melting point:
85-88 °C (lit.)
Boiling point:
389.26°C (rough estimate)
Density 
1.1855 (rough estimate)
refractive index 
1.6450 (estimate)
storage temp. 
-20°C
solubility 
Soluble in water or 1% acetic acid
form 
Fine Crystalline Powder
color 
White to slightly beige
Water Solubility 
insoluble
Sensitive 
Moisture Sensitive
BRN 
2217296
CAS DataBase Reference
58632-95-4(CAS DataBase Reference)
EPA Substance Registry System
Benzeneacetonitrile, .alpha.-[[[(1,1-dimethylethoxy)carbonyl]oxy]imino]- (58632-95-4)
More
Less

Safety

Hazard Codes 
Xn,Xi
Risk Statements 
36/37/38-20/21/22
Safety Statements 
22-24/25-36/37/39-26-36
RIDADR 
3276
WGK Germany 
3
RTECS 
DA0513600
F 
10-21
TSCA 
Yes
HazardClass 
6.1
PackingGroup 
III
HS Code 
29280090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
193372
Product name
2-(Boc-oxyimino)-2-phenylacetonitrile
Purity
99%
Packaging
5g
Price
$27.18
Updated
2024/03/01
Sigma-Aldrich
Product number
193372
Product name
2-(Boc-oxyimino)-2-phenylacetonitrile
Purity
99%
Packaging
25g
Price
$48.5
Updated
2024/03/01
TCI Chemical
Product number
B0988
Product name
2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile
Purity
>98.0%(N)
Packaging
5g
Price
$25
Updated
2024/03/01
TCI Chemical
Product number
B0988
Product name
2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile
Purity
>98.0%(N)
Packaging
25g
Price
$73
Updated
2024/03/01
Alfa Aesar
Product number
A18906
Product name
Boc-ON, 98+%
Packaging
5g
Price
$33.65
Updated
2024/03/01
More
Less

2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile Chemical Properties,Usage,Production

Chemical Properties

White to off-white microcrystalline powder

Uses

Widely used for protection of amino groups in peptide synthesis and multi-step organic synthesis of small molecules.

Synthesis Reference(s)

Organic Syntheses, Coll. Vol. 6, p. 199, 1988
Tetrahedron Letters, 16, p. 4393, 1975 DOI: 10.1016/S0040-4039(00)91133-X

Purification Methods

Triturate the solid with 90% aqueous MeOH, filter, wash with 90% aqueous MeOH and dry it in a vacuum. Recrystallise it from MeOH (needles or plates), but use warm MeOH and cool to crystallise; do not boil as it decomposes slowly. IR has max 1785 (C=O) cm-1 and NMR (CDCl3) usually shows two tert-butyl singlets for syn and anti isomers. Store it in a brown bottle (fridge). It evolves CO2 at room temperature (stoppered bottle can explode!), but can be stored over silica gel which may extend its useful life to more than a year. [Itoh et al. Org Synth 59 95 1980.]

2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

tert-Butyl 2-(methylamino)ethylcarbamate
More
Less

2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile Suppliers

Americas 1 Belgium 3 China 199 Europe 3 France 1 Germany 8 India 9 Japan 6 Russia 1 Slovakia 1 Switzerland 3 United Kingdom 16 United States 48 Global 299
HBCChem, Inc.
Tel
+1-510-219-6317
Fax
+1-650-486-1361
Email
sales@hbcchem.com
Country
United States
ProdList
10648
Advantage
60
Alfa Chemistry
Tel
1-516-6625404
Fax
1-516-927-0118
Email
support@alfa-chemistry.com
Country
United States
ProdList
9171
Advantage
60
BOC Sciences
Tel
16314854226; +16314854226
Email
inquiry@bocsci.com
Country
United States
ProdList
19741
Advantage
58
Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63687
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
Synthonix Inc
Tel
--
Fax
--
Email
info@synthonix.com
Country
United States
ProdList
6872
Advantage
58
ApexBio Technology
Tel
--
Fax
--
Email
sales@apexbt.com
Country
United States
ProdList
6251
Advantage
58
TCI America, Inc. (Tokyo Chemical Industry Co., Ltd.)
Tel
--
Fax
--
Email
.Crew@tcichemicals.com
Country
United States
ProdList
3164
Advantage
58
MP Biomedicals, LLC. (Division of Valiant FC Co., Ltd.)
Tel
--
Fax
--
Email
serv@mpbio.com
Country
United States
ProdList
1854
Advantage
58
MilliporeSigma (Sigma-Aldrich Corp.)
Tel
--
Fax
--
Email
@sial.com
Country
United States
ProdList
5414
Advantage
58
Fluorochem Ltd.
Tel
--
Fax
--
Email
enquiries@fluorochem.co.uk
Country
United States
ProdList
4583
Advantage
58
Alichem Inc.
Tel
--
Fax
--
Email
sales@alichem.com
Country
United States
ProdList
6167
Advantage
58
Advanced Synthesis S.A.
Tel
--
Fax
--
Country
United States
ProdList
249
Advantage
58
Chem-Impex International, Inc. (CII)
Tel
--
Fax
--
Email
Customer@chemimpex.com
Country
United States
ProdList
893
Advantage
58
Oakwood Products, Inc.
Tel
--
Fax
--
Email
sales@oakwoodchemical.com
Country
United States
ProdList
6193
Advantage
74
AAPPTEC
Tel
--
Fax
--
Email
info@aapptec.com
Country
United States
ProdList
533
Advantage
0
Chiral Management
Tel
--
Fax
--
Email
sales@chiralmanagement.com
Country
United States
ProdList
1332
Advantage
30
VWR International, LLC.
Tel
--
Fax
--
Email
@sargentwelch.com
Country
United States
ProdList
6262
Advantage
58
United States Biological
Tel
--
Fax
--
Email
chemicals@usbio.net
Country
United States
ProdList
6214
Advantage
80
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
TCI America
Tel
--
Fax
--
Email
sales@tciamerica.com
Country
United States
ProdList
6909
Advantage
75
Frontier Scientific, Inc.
Tel
--
Fax
--
Email
sales@frontiersci.com
Country
United States
ProdList
6222
Advantage
86
CarboMer, Inc.
Tel
--
Fax
--
Email
sales@carbomer.com
Country
United States
ProdList
4026
Advantage
67
Anisyn, Inc.
Tel
--
Fax
--
Email
sales@anisyn.com
Country
United States
ProdList
863
Advantage
0
AAT Pharmaceutical, LLC
Tel
--
Fax
--
Email
sales@aatpharm.com
Country
United States
ProdList
209
Advantage
60
Santa Cruz Biotechnology, Inc.
Tel
--
Fax
--
Email
scbt@scbt.com
Country
United States
ProdList
3597
Advantage
60
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6962
Advantage
56
Chem-Impex International, Inc.
Tel
--
Fax
--
Country
United States
ProdList
6730
Advantage
64
Ivy Fine Chemicals
Tel
--
Fax
--
Email
sales@ivychem.com
Country
United States
ProdList
6493
Advantage
58
AK Scientific, Inc.
Tel
--
Fax
--
Email
sales@aksci.com
Country
United States
ProdList
6347
Advantage
65
Alfa Aesar
Tel
--
Fax
--
Email
tech@alfa.com
Country
United States
ProdList
6814
Advantage
81
Waterstone Technology, LLC
Tel
--
Fax
--
Email
sales@waterstonetech.com
Country
United States
ProdList
6786
Advantage
30
Jupiter Bioscience Limited
Tel
--
Fax
--
Email
vksaipriya@jupiterbioscience.com
Country
United States
ProdList
247
Advantage
68
HONEST JOY HOLDINGS LIMITED
Tel
--
Fax
--
Email
sales@honestjoy.cn
Country
United States
ProdList
6675
Advantage
54
2A PharmaChem USA
Tel
--
Fax
--
Email
sales@2apharmachem.com
Country
United States
ProdList
6137
Advantage
39
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6718
Advantage
47
APAC Pharmaceutical, LLC
Tel
--
Fax
--
Email
sales@apacpharma.com
Country
United States
ProdList
6322
Advantage
38
www.vwrsp.com
Tel
--
Fax
--
Email
B2B@VWR.com
Country
United States
ProdList
622
Advantage
86
Wintersun Chemical
Tel
--
Fax
--
Email
purchasing@wintersunchem.com
Country
United States
ProdList
776
Advantage
68
Advance Scientific & Chemical
Tel
--
Fax
--
Email
sales@advance-scientific.com
Country
United States
ProdList
6419
Advantage
71
Beta Pharma, Inc.
Tel
--
Fax
--
Email
sales@betapharma.com
Country
United States
ProdList
6226
Advantage
60
BOSCHE SCIENTIFIC, LLC
Tel
--
Fax
--
Email
Sales@BoscheSci.com
Country
United States
ProdList
6477
Advantage
55
Atlantic SciTech Group, Inc.
Tel
--
Fax
--
Email
sales@astginc.com
Country
United States
ProdList
2308
Advantage
43
AB Chem Technologies, LLC
Tel
--
Fax
--
Email
sales@abchemtech.com
Country
United States
ProdList
1101
Advantage
46
HW Sands Corp.
Tel
--
Fax
--
Email
customerservice@hwsands.com
Country
United States
ProdList
674
Advantage
60
Spectrum Chemicals & Laboratory Products
Tel
--
Fax
--
Email
sales@spectrumchemical.com
Country
United States
ProdList
6699
Advantage
77
MP Biomedicals, Inc.
Tel
--
Fax
--
Country
United States
ProdList
6561
Advantage
81
More
Less

View Lastest Price from 2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile 58632-95-4
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2022-09-26
Zhuozhou Wenxi import and Export Co., Ltd
Product
2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile 58632-95-4
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile 58632-95-4
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-08

58632-95-4, 2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrileRelated Search:

4-tert-Butylcatechol tert-Butyllithium N-Carbobenzyloxyglycine 4-tert-Butylphenol tert-Butyl methyl ether tert-Butyldimethylsilyl chloride (3-Methoxyphenyl)acetonitrile Diphenylacetonitrile Methyl 4-tert-butylbenzoate tert-Butanol tert-Butyl hydroperoxide Benzeneacetonitrile Carbonyl iron powder Formic acid isopropyl ester Acetaldoxime 2-HYDROXYIMINO-2-PHENYLACETONITRILE FORMOXIME O-methylhydroxylamine

  • alpha-[[[(1,1-dimethylethoxy)carbonyl]oxy]imino]-benzeneacetonitril
  • N-TERT-BUTOXYCARBONYLOXYIMINO-2-PHENYLACETONITRILE
  • 2-(tert-Butoxycarbon
  • Boc-ON 2-(tert-ButoxycarbonyloxyiMino)-2-phenylacetonitrile
  • N-((tert-Butoxycarbonyl)oxy)benziMidoyl cyanide
  • BOC-ON, 99% 25GR
  • BOC-ON, 99% 5GR
  • 2-(<i>tert</i>-Butoxycarbonyloxyimino)-2-phenylacetonitrile
  • 2-(Boc-oxyimino)-2-phenylacetonitrile 99%
  • 2-tert-Butyloxycarbonyloxyimino-2-phenyl acetonitrile≥ 99% (HPLC)
  • 2-(tert-BOC-Oxyimino)-2-phenylacetonitrile for synthesis
  • carbonic acid tert-butyl [(E)-[cyano(phenyl)methylidene]amino] ester
  • LABOTEST-BB LT00159655
  • 2-(BOC-OXYIMINO)-2-PHENYLACETONITRILE
  • 2-(TERT-BUTOXYCARBONYLOXYIMINO)-2-PHENYLACETONITRILE
  • 2-(T-BUTOXYCARBONYLOXYIMINO)-2-PHENYLACETONITRILE
  • 2-T-BUTYLOXYCARBONYLOXYIMINO-2-PHENYL ACETONITRILE
  • 2-(Boc-oxyimino)-2-phenylacetonitrile~2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile
  • BOC-ON (2-t-butoxycarbonyloxyimino)-2-phenylacetonitirle)
  • N-T-butoxycarbonyloxyimino-2-*phenylacetonitrile
  • tert-butyl alpha-cyanobenzylaminyl carbonate
  • BOC-ON (N-TERT-BUTOXYCARBONYLOXYIMINO-2- PHENYLACETONITRILE)
  • 2-tert-Butyloxycarbonyloxyimino-2-phenyl acetonitrile
  • Boc-ON, 98+%
  • 2-Butoxycarbonyloximino-2-phenylacetonitrile
  • [(CYANO-PHENYL-METHYLIDENE)AMINO] TERT-BUTYL CARBONATE
  • Boc-On99%
  • BOC-ON
  • Boc-ON 2-t-Butyloxycarbonyloxyimino-2-phenyl acetonitrile
  • Benzeneacetonitrile, alpha-[[[(1,1-dimethylethoxy)carbonyl]oxy]imino]-
  • tert-Butyl [(cyano-phenylmethylidene)amino] carbonate
  • 2-(t-Butyloxycarbonyl imino)-2-phenylacetonitrile
  • Carbonic acid, (cyanophenylmethylene)azanyl 1,1-dimethylethyl ester
  • 2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile &gt
  • 2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile USP/EP/BP
  • tert-butyl [(E)-[cyano(phenyl)methylidene]amino] carbonate
  • 58632-95-4
  • CH33COCOONCC6H5CN
  • Protecting and Derivatizing Reagents
  • Synthetic Reagents
  • Others
  • Protection and Derivatization
  • Peptide Synthesis
  • Protective Reagents (Peptide Synthesis)
  • Protection & Derivatization Reagents (for Synthesis)
  • Biochemistry
  • Peptide Synthesis
  • Protection & Derivatization Reagents (for Synthesis)
  • Protective Reagents (Peptide Synthesis)
  • Synthetic Organic Chemistry
  • Boc-Amino acid series
  • Pharmaceutical Raw Materials