ChemicalBook > CAS DataBase List > 4-(Trifluoromethyl)benzophenone

4-(Trifluoromethyl)benzophenone

Product Name
4-(Trifluoromethyl)benzophenone
CAS No.
728-86-9
Chemical Name
4-(Trifluoromethyl)benzophenone
Synonyms
11β-HSD1-IN-7;Phenyl(4-(trifluoromethyl);P-TRIFLUOROMETHYL BENZOPHENONE;4'-Trifluoromethylbenzophenone;4-(TRIFLUOROMETHYL)BENZOPHENONE;4-(Trifluoromethyl)benzophenone97%;4-(TRIFLUOROMETHYL)BENZOPHENONE 97%;4-(Trifluoromethyl)benzophenone, 98+%;Phenyl[4-(trifluoromethyl)phenyl] ketone;PHENYL[4-(TRIFLUOROMETHYL)PHENYL]METHANONE
CBNumber
CB8765628
Molecular Formula
C14H9F3O
Formula Weight
250.22
MOL File
728-86-9.mol
More
Less

4-(Trifluoromethyl)benzophenone Property

Melting point:
114-116 °C(lit.)
Boiling point:
309.2±42.0 °C(Predicted)
Density 
1.2778 (estimate)
storage temp. 
Sealed in dry,Room Temperature
form 
Crystalline Solid
color 
Off-white to beige
BRN 
1879572
InChI
InChI=1S/C14H9F3O/c15-14(16,17)12-8-6-11(7-9-12)13(18)10-4-2-1-3-5-10/h1-9H
InChIKey
OHTYZZYAMUVKQS-UHFFFAOYSA-N
SMILES
C(C1=CC=CC=C1)(C1=CC=C(C(F)(F)F)C=C1)=O
CAS DataBase Reference
728-86-9(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39-24/25
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29147000
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

TRC
Product number
T797060
Product name
4-(Trifluoromethyl)benzophenone
Packaging
100mg
Price
$60
Updated
2021/12/16
Oakwood
Product number
007595
Product name
4-(Trifluoromethyl)benzophenone
Purity
98%
Packaging
250mg
Price
$10
Updated
2021/12/16
Matrix Scientific
Product number
005393
Product name
4-(Trifluoromethyl)benzophenone
Purity
97%
Packaging
1g
Price
$14
Updated
2021/12/16
SynQuest Laboratories
Product number
2817-3-34
Product name
4-(Trifluoromethyl)benzophenone
Purity
98%
Packaging
2g
Price
$15
Updated
2021/12/16
Oakwood
Product number
007595
Product name
4-(Trifluoromethyl)benzophenone
Purity
98%
Packaging
1g
Price
$15
Updated
2021/12/16
More
Less

4-(Trifluoromethyl)benzophenone Chemical Properties,Usage,Production

Chemical Properties

OFF-WHITE TO BEIGE CRYSTALLINE SOLID

Uses

11β-HSD1-IN-7 (compound c10a) is a 11β HSD1 inhibitor with an IC50 value of 1.9 μM for human 11β HSD1. 11β-HSD1-IN-7 can be used for the research of diabetes and cognitive decline[1].

Synthesis

A solution of diphenylmethanol (1 mmol), NBS (1.3equiv.), KOAc (1.5 equiv.) H2O (1.5 mL), and CH2Cl2 (0.5mL) was magnetically stirred in 25 mL flask at room temperaturefor 10 h. The reaction mixture was added into water(10 mL), and extracted with EtOAc (3 × 10 mL). The combinedEtOAc extracts were dried over anhydrous MgSO4,filtrated, and then the solvent was removed under reducedpressure. The residue was purified by the flash columnchromatography on silica gel with PE or PE/EtOAc as theeluent to obtain the desired product 4-(Trifluoromethyl)benzophenone.

References

[1] Naredo-Gonzalez G, et al. Non-invasive in vivo assessment of 11β-hydroxysteroid dehydrogenase type 1 activity by 19F-Magnetic Resonance Spectroscopy. Sci Rep. 2022 Sep 29;12(1):16268. DOI:10.1038/s41598-022-18740-5

4-(Trifluoromethyl)benzophenone Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

4-(Trifluoromethyl)benzophenone Suppliers

Belgium 1 China 52 France 1 Germany 3 India 4 Japan 1 Slovakia 1 Switzerland 1 The Netherlands 1 United Kingdom 11 United States 15 Global 91
JRD Fluorochemicals Ltd
Tel
--
Fax
--
Email
sales@jrdfluoro.co.uk
Country
United Kingdom
ProdList
2774
Advantage
58
Apollo Scientific Ltd.
Tel
--
Fax
--
Email
sales@apolloscientific.co.uk
Country
United Kingdom
ProdList
6084
Advantage
88
Leancare Ltd.
Tel
--
Fax
--
Email
enquiry@leancare.co.uk
Country
United Kingdom
ProdList
6446
Advantage
42
MOLEKULA Ltd.
Tel
--
Fax
--
Email
kevinbanks@molekula.com
Country
United Kingdom
ProdList
6140
Advantage
66
CARBONE SCIENTIFIC CO.,LTD
Tel
--
Fax
--
Email
sales@carbonesci.com
Country
United Kingdom
ProdList
6666
Advantage
30
ETA SCIENTIFIC Co.,Ltd
Tel
--
Fax
--
Email
sales@etascientific.com
Country
United Kingdom
ProdList
6090
Advantage
34
UK GREEN SCIENTIFIC CO.,LIMITED
Tel
--
Fax
--
Email
sales@gs-chem.com
Country
United Kingdom
ProdList
6098
Advantage
47
Fluorochem Ltd
Tel
--
Fax
--
Email
vernam@fluorochem.co.uk
Country
United Kingdom
ProdList
6375
Advantage
65
VWR International
Tel
--
Fax
--
Email
solutions@vwr.com
Country
United Kingdom
ProdList
6548
Advantage
82
JRD Fluorochemicals Ltd.
Tel
--
Fax
--
Email
sales@jrdfluoro.co.uk
Country
United Kingdom
ProdList
1729
Advantage
38
Fluorochem Ltd.
Tel
--
Fax
--
Email
enquiries@fluorochem.co.uk
Country
United Kingdom
ProdList
6401
Advantage
74
More
Less

View Lastest Price from 4-(Trifluoromethyl)benzophenone manufacturers

Speranza Chemical Co., Ltd.
Product
4-(Trifluoromethyl)benzophenone 728-86-9
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
100MT/Year
Release date
2024-11-07

728-86-9, 4-(Trifluoromethyl)benzophenoneRelated Search:

2-FLUORO-4-(TRIFLUOROMETHYL)BENZOPHENONE,2-Fluoro-4-(trifluoromethyl)benzophenone97%,2-Fluoro-4-(trifluoromethyl)benzophenone 97% 4-(Trifluoromethyl)benzophenone 3-FLUORO-4-(TRIFLUOROMETHYL)BENZOPHENONE 3,4'-Bis(trifluoromethyl)benzophenone98%,3,4'-BIS(TRIFLUOROMETHYL)BENZOPHENONE,3,4'-DI(TRIFLUOROMETHYL)BENZOPHENONE,3,4'-Bis(trifluoromethyl)benzophenone 98% 2-(TRIFLUOROMETHYL)BENZOPHENONE,2-(Trifluoromethyl)benzophenone98%,2-(TRIFLUOROMETHYL)BENZOPHENONE 99% 4-FLUORO-3-(TRIFLUOROMETHYL)BENZOPHENONE 3-(Trifluoromethyl)benzophenone98%,3-(TRIFLUOROMETHYL)BENZOPHENONE,3-(TRIFLUOROMETHYL)BENZOPHENONE 99% 3,3',5,5'-Tetrakis(trifluoromethyl)benzophenone 97%,3,3',5,5'-TETRAKIS(TRIFLUOROMETHYL)BENZOPHENONE,3,3',5,5'-Tetrakis(trifluoromethyl)benzophenone97% 2-Fluoro-6-(trifluoromethyl)benzophenone97%,2-FLUORO-6-(TRIFLUOROMETHYL)BENZOPHENONE 3,3'-BIS(TRIFLUOROMETHYL)BENZOPHENONE, 9 8%,3,3'-Bis(trifluoromethyl)benzophenone 98%,3,3'-BIS(TRIFLUOROMETHYL)BENZOPHENONE,3,3'-DI(TRIFLUOROMETHYL)BENZOPHENONE 2,2'-DICHLORO-5,5'-BIS-TRIFLUOROMETHYL-BENZOPHENONE 3-FLUORO-5-(TRIFLUOROMETHYL)BENZOPHENONE 2-Chloro-5-(trifluoromethyl)benzophenone 97%,2-Chloro-5-(trifluoromethyl)benzophenone97%,2-CHLORO-5-(TRIFLUOROMETHYL)BENZOPHENONE 2-FLUORO-3-(TRIFLUOROMETHYL)BENZOPHENONE,2-Fluoro-3-(trifluoromethyl)benzophenone 97%,2-Fluoro-3-(trifluoromethyl)benzophenone97% 2-Fluoro-5-(trifluoromethyl)benzophenone 97%,2-FLUORO-5-(TRIFLUOROMETHYL)BENZOPHENONE,2-Fluoro-5-(trifluoromethyl)benzophenone97% 3,5-Bis(trifluoromethyl)benzophenone 97%,3,5-BIS(TRIFLUOROMETHYL)BENZOPHENONE,3,5-DI(TRIFLUOROMETHYL)BENZOPHENONE Benzophenone METHOXYPHENONE

  • 4-(TRIFLUOROMETHYL)BENZOPHENONE
  • 4-(TRIFLUOROMETHYL)BENZOPHENONE 97%
  • 4-(Trifluoromethyl)benzophenone97%
  • 4-(Trifluoromethyl)benzophenone, 98+%
  • Phenyl[4-(trifluoromethyl)phenyl] ketone
  • Phenyl(4-(trifluoromethyl)
  • Methanone, phenyl[4-(trifluoromethyl)phenyl]-
  • PHENYL[4-(TRIFLUOROMETHYL)PHENYL]METHANONE
  • P-TRIFLUOROMETHYL BENZOPHENONE
  • (4-(trifluoromethyl)phenyl)(phenyl)methanone
  • 11β-HSD1-IN-7
  • 4'-Trifluoromethylbenzophenone
  • 728-86-9
  • CF3C6H4COC6H5
  • C14H9F3O
  • Ketones
  • KETONE
  • Building Blocks
  • Carbonyl Compounds
  • C13 to C14
  • Organic Building Blocks