N-DESMETHYLCITALOPRAM HYDROCHLORIDE

Product Name: N-DESMETHYLCITALOPRAM HYDROCHLORIDE
CAS No.: 144025-14-9
Chemical Name: N-DESMETHYLCITALOPRAM HYDROCHLORIDE
Synonyms: DEMETHYLCITALOPRAM;S-Desmethylcitalopram;N-Desmethyl Citalopram;rac Demethyl Citalopram;CitalopraM EP IMpurity D;N-Desmethyl Escitalopram;Escitalopram N-Desmethyl;N-Desmethylcitalopram HCl;(S)-(+)-N-Demethylcitalopram;EsCitalopram N-Desmethyl HCl
CBNumber: CB8773223
Molecular Formula: C19H19FN2O
Formula Weight: 310.37
MOL File: 144025-14-9.mol

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N-DESMETHYLCITALOPRAM HYDROCHLORIDE Property

Melting point:: 60-65°C
Boiling point:: 429.4±45.0 °C(Predicted)
Density: 1.20±0.1 g/cm3(Predicted)
Flash point:: 9℃
storage temp.: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
pka: 10.50±0.10(Predicted)
Stability:: Hygroscopic

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Safety

Hazard Codes: F,T
Risk Statements: 11-23/24/25-39/23/24/25
Safety Statements: 16-36/37-45
RIDADR: UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany: 1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H370Causes damage to organs

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P311Call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: D-047
Product name: N-Desmethylcitalopram hydrochloride solution
Purity: 1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant?
Packaging: 1mL
Price: $191
Updated: 2024/03/01

Medical Isotopes, Inc.

Product number: 8812
Product name: racDemethylCitalopramHCl
Packaging: 1mg
Price: $290
Updated: 2021/12/16

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N-DESMETHYLCITALOPRAM HYDROCHLORIDE Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

N-Desmethylcitalopram hydrochloride is a metabolite of Citalopram, an inhibitor of serotonin (5-HT) uptake. Used as an antidepressant.

General Description

N-Desmethylcitalopram is an active metabolite of the SSRI antidepressant drug citalopram. Citalopram, marketed as Celexa^? in the US and Canada, is used to treat major depression associated with mood disorders.

N-DESMETHYLCITALOPRAM HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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N-DESMETHYLCITALOPRAM HYDROCHLORIDE Suppliers

Canada 1 China 31 Germany 1 India 10 United States 6 Global 49

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

Chemsky (shanghai) International Co.,Ltd

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 15402
Advantage: 60

Artis Chemistry (Shanghai) Co. Ltd.

Tel: 86-21-60936353
Fax: 86-21-60936352
Country: China
ProdList: 335
Advantage: 58

Clearsynth Labs Limited

Tel: +91-22-26355700
Fax: +91-22-26355701
Email: info@clearsynth.com
Country: India
ProdList: 9679
Advantage: 58

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 18070
Advantage: 56

Shanghai Kewel Chemical Co., Ltd.

Tel: 021-64609169 18901607656
Fax: 021-64609160
Email: greensnown@163.com
Country: China
ProdList: 9906
Advantage: 50

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51456
Advantage: 80

Nanjing XiZe Biotechnology CO., Ltd.

Tel: 025-66023220 0086-15250997978
Fax: 025-58362220
Email: 1511893459@qq.com
Country: China
ProdList: 7892
Advantage: 55

Tonichem Pharmaceutical Technology Co., Ltd.

Tel: +86 (0752) 222-7171, +86 15815821171
Fax: +86 (0752) 222-6171
Country: China
ProdList: 1120
Advantage: 58

Shanghai Champ Biopharmaceuticals Co., Ltd.

Tel: 021-61537865 13585780846
Email: sales@champchem.com
Country: China
ProdList: 360
Advantage: 58

144025-14-9, N-DESMETHYLCITALOPRAM HYDROCHLORIDERelated Search:

CitalopraM DiMethylaMinobutanone 5-BroModescyano CitalopraM 5-chloro-1-(3-diMethylaMinopropyl)-1-(4-fluorophenyl)-phthalan Citalopram (R)-Desmethyl Citalopram Hydrochloride (S)-(+)-N-Demethylcitalopram Hydrochloride (S)-(+)-CITALOPRAM-D4 OXALATE Escitalopram S-(+)-N-TRIFLUOROACETODESMETHYLCITALOPRAM S-(+)-N-TRIFLUOROACETODIDEMETHYLCITALOPRAM N-DESMETHYLCITALOPRAM HYDROCHLORIDE

DEMETHYLCITALOPRAM

1-(4-Fluoro-phenyl)-1-(3-methylamino-propyl)-1,3-dihydro-isobenzofuran-5-carbonitril

rac Demethyl Citalopram

S-Desmethylcitalopram

1-(4-Fluoro-phenyl)-1-(3-methylamino-propyl)-1,3-dihydro-isobenzofuran-5-carbonitrile Hydrochloride

Citalopram impurity 4/Citalopram EP Impurity D HCl/(S)-N-Desmethyl Citalopram Hydrochloride

racDemethyl Citalopram Hydrochloride

1-(4-Fluoro-phenyl)-1-(3-methylamino-propyl)-1,3-dihydro-isobenzofuran-5-carbonitrile

rac Demethyl CitalopramDiscontinued See: D230846

(1S)-1-(4-Fluorophenyl)-1,3-dihydro-1-[3-(methylamino)propyl]-5-isobenzofurancarbonitrile

(S)-(+)-N-Demethylcitalopram

(S)-1-(3-Methylaminopropyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile

S-Desmethyl CitalopramDiscontinued See D291571

S-Desmethyl CitalopramCL (or it can be made as xylate)

N-Desmethylcitalopram HCl

(S)-(+)-DesMethyl CitalopraM-d4

CitalopraM EP IMpurity D

N-Desmethyl Citalopram D4 Hydrochloride (Racemic)

N-Desmethylcitalopram hydrochloride solution

N-Desmethyl Escitalopram

1-(3-Methylaminopropyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile

1-(4-Fluorophenyl)-1-[3-(Methylamino)Propyl]-1,3-Dihydro-2-Benzofuran-5-Carbonitrile

Citalopram N-Desmethyl S-Isomer HCl

EsCitalopram N-Desmethyl HCl

Citalopram Impurity 6(Citalopram EP Impurity D)

Escitalopram N-Desmethyl

5-Isobenzofurancarbonitrile, 1-(4-fluorophenyl)-1,3-dihydro-1-[3-(methylamino)propyl]-, (1S)-

Citalopram Impurity 6（EP Impurity D）

N-Desmethyl Escitalopram Oxalate

Citalopram N-Desmethyl S-Isomer

N-Desmethyl Citalopram

N-Desmethylcitalopram HCl (1.0 mg/mL) (as free base) in Methanol

N-DESMETHYLCITALOPRAM HYDROCHLORIDE

( S )-(+)- N -Demethylcitalopram/(S)-N-Desmethyl Citalopram Hydrochloride

144025-14-9

C19H20ClFN2O

Chiral Reagents

Intermediates & Fine Chemicals

Metabolites & Impurities

Pharmaceuticals

Various Metabolites and Impurities