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N-DESMETHYLCITALOPRAM HYDROCHLORIDE

Product Name
N-DESMETHYLCITALOPRAM HYDROCHLORIDE
CAS No.
144025-14-9
Chemical Name
N-DESMETHYLCITALOPRAM HYDROCHLORIDE
Synonyms
DEMETHYLCITALOPRAM;S-Desmethylcitalopram;N-Desmethyl Citalopram;rac Demethyl Citalopram;CitalopraM EP IMpurity D;N-Desmethyl Escitalopram;Escitalopram N-Desmethyl;N-Desmethylcitalopram HCl;(S)-(+)-N-Demethylcitalopram;EsCitalopram N-Desmethyl HCl
CBNumber
CB8773223
Molecular Formula
C19H19FN2O
Formula Weight
310.37
MOL File
144025-14-9.mol
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N-DESMETHYLCITALOPRAM HYDROCHLORIDE Property

Melting point:
60-65°C
Boiling point:
429.4±45.0 °C(Predicted)
Density 
1.20±0.1 g/cm3(Predicted)
Flash point:
9℃
storage temp. 
Hygroscopic, -20°C Freezer, Under Inert Atmosphere
pka
10.50±0.10(Predicted)
Stability:
Hygroscopic
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Safety

Hazard Codes 
F,T
Risk Statements 
11-23/24/25-39/23/24/25
Safety Statements 
16-36/37-45
RIDADR 
UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany 
1
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H370Causes damage to organs

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P311Call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D-047
Product name
N-Desmethylcitalopram hydrochloride solution
Purity
1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant?
Packaging
1mL
Price
$191
Updated
2024/03/01
Medical Isotopes, Inc.
Product number
8812
Product name
racDemethylCitalopramHCl
Packaging
1mg
Price
$290
Updated
2021/12/16
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N-DESMETHYLCITALOPRAM HYDROCHLORIDE Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

N-Desmethylcitalopram hydrochloride is a metabolite of Citalopram, an inhibitor of serotonin (5-HT) uptake. Used as an antidepressant.

General Description

N-Desmethylcitalopram is an active metabolite of the SSRI antidepressant drug citalopram. Citalopram, marketed as Celexa? in the US and Canada, is used to treat major depression associated with mood disorders.

N-DESMETHYLCITALOPRAM HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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N-DESMETHYLCITALOPRAM HYDROCHLORIDE Suppliers

Canada 1 China 31 Germany 1 India 10 United States 6 Global 49
Toronto Research Chemicals
Tel
--
Fax
--
Email
info@trc-canada.com
Country
Canada
ProdList
6038
Advantage
71

144025-14-9, N-DESMETHYLCITALOPRAM HYDROCHLORIDERelated Search:

CitalopraM DiMethylaMinobutanone 5-BroModescyano CitalopraM 5-chloro-1-(3-diMethylaMinopropyl)-1-(4-fluorophenyl)-phthalan Citalopram (R)-Desmethyl Citalopram Hydrochloride (S)-(+)-N-Demethylcitalopram Hydrochloride (S)-(+)-CITALOPRAM-D4 OXALATE Escitalopram S-(+)-N-TRIFLUOROACETODESMETHYLCITALOPRAM S-(+)-N-TRIFLUOROACETODIDEMETHYLCITALOPRAM N-DESMETHYLCITALOPRAM HYDROCHLORIDE

  • DEMETHYLCITALOPRAM
  • 1-(4-Fluoro-phenyl)-1-(3-methylamino-propyl)-1,3-dihydro-isobenzofuran-5-carbonitril
  • rac Demethyl Citalopram
  • S-Desmethylcitalopram
  • 1-(4-Fluoro-phenyl)-1-(3-methylamino-propyl)-1,3-dihydro-isobenzofuran-5-carbonitrile Hydrochloride
  • Citalopram impurity 4/Citalopram EP Impurity D HCl/(S)-N-Desmethyl Citalopram Hydrochloride
  • racDemethyl Citalopram Hydrochloride
  • 1-(4-Fluoro-phenyl)-1-(3-methylamino-propyl)-1,3-dihydro-isobenzofuran-5-carbonitrile
  • rac Demethyl CitalopramDiscontinued See: D230846
  • (1S)-1-(4-Fluorophenyl)-1,3-dihydro-1-[3-(methylamino)propyl]-5-isobenzofurancarbonitrile
  • (S)-(+)-N-Demethylcitalopram
  • (S)-1-(3-Methylaminopropyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile
  • S-Desmethyl CitalopramDiscontinued See D291571
  • S-Desmethyl CitalopramCL (or it can be made as xylate)
  • N-Desmethylcitalopram HCl
  • (S)-(+)-DesMethyl CitalopraM-d4
  • CitalopraM EP IMpurity D
  • N-Desmethyl Citalopram D4 Hydrochloride (Racemic)
  • N-Desmethylcitalopram hydrochloride solution
  • N-Desmethyl Escitalopram
  • 1-(3-Methylaminopropyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile
  • 1-(4-Fluorophenyl)-1-[3-(Methylamino)Propyl]-1,3-Dihydro-2-Benzofuran-5-Carbonitrile
  • Citalopram N-Desmethyl S-Isomer HCl
  • EsCitalopram N-Desmethyl HCl
  • Citalopram Impurity 6(Citalopram EP Impurity D)
  • Escitalopram N-Desmethyl
  • 5-Isobenzofurancarbonitrile, 1-(4-fluorophenyl)-1,3-dihydro-1-[3-(methylamino)propyl]-, (1S)-
  • Citalopram Impurity 6（EP Impurity D）
  • N-Desmethyl Escitalopram Oxalate
  • Citalopram N-Desmethyl S-Isomer
  • N-Desmethyl Citalopram
  • N-Desmethylcitalopram HCl (1.0 mg/mL) (as free base) in Methanol
  • N-DESMETHYLCITALOPRAM HYDROCHLORIDE
  • ( S )-(+)- N -Demethylcitalopram/(S)-N-Desmethyl Citalopram Hydrochloride
  • 144025-14-9
  • C19H20ClFN2O
  • Chiral Reagents
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
  • Various Metabolites and Impurities