ChemicalBook > CAS DataBase List > Sodium hydroxymethanesulphinate

Sodium hydroxymethanesulphinate

Product Name
Sodium hydroxymethanesulphinate
CAS No.
149-44-0
Chemical Name
Sodium hydroxymethanesulphinate
Synonyms
RONGALITE;SODIUM FORMALDEHYDE SULFOXYLATE;SODIUM HYDROXYMETHANESULFINATE;RONGALITE C;SODIUM FORMALDEHYDESULFOXALATE;Natriumhydroxymethansulfinat;Sodiumbisulfoxylateformaldehyde;Sodium hydroxymethanesulfinate hydrate;HYDROXYMETHANESULFINIC ACID SODIUM SALT;aldanil
CBNumber
CB8773339
Molecular Formula
CH3NaO3S
Formula Weight
118.09
MOL File
149-44-0.mol
More
Less

Sodium hydroxymethanesulphinate Property

Melting point:
~120 °C (dec.)
Density 
1.744[at 20℃]
vapor pressure 
0.003Pa at 20℃
Flash point:
>100℃
storage temp. 
Inert atmosphere,Room Temperature
solubility 
H2O: 50 mg/mL, clear, colorless
form 
Solid
color 
White to Off-White
PH
9.5-10.5
Odor
Mild garlic odor
Water Solubility 
soluble H2O, alcohol [HAW93]
Merck 
14,8620
Stability:
Stable. Incompatible with strong oxidizing agents.
LogP
-3.4 at 22℃
EPA Substance Registry System
Sodium sulfoxylate formaldehyde (anhydrous) (149-44-0)
More
Less

Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-68-31
Safety Statements 
26-36-36/37
WGK Germany 
1
RTECS 
PB0380000
TSCA 
Yes
HS Code 
2930909899
Hazardous Substances Data
149-44-0(Hazardous Substances Data)
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H341Suspected of causing genetic defects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

More
Less

N-Bromosuccinimide Price

TCI Chemical
Product number
R0053
Product name
Sodium Hydroxymethanesulfinate Dihydrate
Purity
>97.0%(T)
Packaging
500g
Price
$28
Updated
2022/04/27
Alfa Aesar
Product number
A15731
Product name
Hydroxymethanesulfinic acid sodium salt hydrate, tech 85%, cont. up to 5% sodium sulfite (dry wt.)
Packaging
500g
Price
$30.65
Updated
2024/03/01
Alfa Aesar
Product number
A15731
Product name
Hydroxymethanesulfinic acid sodium salt hydrate, tech 85%, cont. up to 5% sodium sulfite (dry wt.)
Packaging
2500g
Price
$118.65
Updated
2024/03/01
TRC
Product number
S634953
Product name
Sodium hydroxymethanesulfinate hydrate
Packaging
10g
Price
$135
Updated
2021/12/16
Usbiological
Product number
279673
Product name
Sodium hydroxymethanesulfinate hydrate
Packaging
250g
Price
$319
Updated
2021/12/16
More
Less

Sodium hydroxymethanesulphinate Chemical Properties,Usage,Production

Chemical Properties

white solid; used as stripping and discharge agent for textiles [HAW93]

Chemical Properties

When freshly prepared, sodium formaldehyde sulfoxylate occurs as white, odorless crystals, which quickly develop a characteristic garlic odor on standing.

Uses

Pharmaceutic aid (preservative).

Uses

Sodium Hydroxymethanesulfinate Hydrate is the hydrated version of Sodium Hydroxymethanesulfinate (S634950), which is an organic reductant that is stable in alkaline enviroments but readily decomposes in acidic medium to produce a number of products, one of them being sulfur dioxide. Sodium hydroxymethanesulfinate is also used in conjunction with substituted anilines (e.g. p-Anisidine [A673505]) to synthesize anilinomethanesulfonates.

Production Methods

Sodium formaldehyde sulfoxylate is manufactured from sodium dithionate and formaldehyde in water.

Flammability and Explosibility

Non flammable

Pharmaceutical Applications

Sodium formaldehyde sulfoxylate is a water-soluble antioxidant and is generally used as the dihydrate. It is used in the formulation of injection products at a level of up to 0.1% w/v in the final preparation administered to the patient.

Safety

The toxicological properties of sodium formaldehyde sulfoxylate have not been fully investigated. However, it is used in the formulation of injection products at a level to 0.1% w/v in the final preparation administered to the patient.
Sodium formaldehyde sulfoxylate is moderately toxic by ingestion, and when heated to decomposition it emits toxic fumes of sulfur dioxide and sodium oxide.
LD50 (mouse, oral): 4 g/kg
LD50 (rat, IP): >2 g/kg
LD50 (rat, oral): >2 g/kg

storage

Store in well-closed, light-resistant containers at controlled room temperature (15–30℃).

Purification Methods

It crystallises from H2O as the dihydrate and decomposes at higher temperatures. Store it in a closed container in a cool place. It is insoluble in EtOH and Et2O and is a good reducing agent. [X-ray structure: Tuter J Chem Soc 3064 1955.] Note that this compound {HOCH2SO2Na} should not be confused with formaldehyde sodium bisulfite adduct {HOCH2SO3Na} from which it is prepared by reduction with Zn. [Beilstein 1 IV 3052.]

Incompatibilities

Sodium formaldehyde sulfoxylate is incompatible with strong oxidizing agents; it is decomposed by dilute acid.

Regulatory Status

Included in the FDA Inactive Ingredients Database (parenteral products up to 0.1% via the IM, IV, and SC routes). Included in the Canadian List of Acceptable Non-medicinal Ingredients.

Sodium hydroxymethanesulphinate Preparation Products And Raw materials

Raw materials

ZINC ZINC HYDROSULFITE Sulfur dioxide Formaldehyde Zinc hydroxide Sodium hydroxide

Preparation Products

More
Less

Sodium hydroxymethanesulphinate Suppliers

Australia 1 Canada 2 China 198 Czech Republic 1 Europe 3 France 2 Germany 4 India 36 Italy 3 Japan 7 Russia 1 Slovakia 1 South Korea 2 Spain 1 Switzerland 1 Turkey 2 United Kingdom 9 United States 33 Global 307
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12443
Advantage
60
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18738
Advantage
57
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11707
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14435
Advantage
57
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11707
Advantage
57
Spectrum Chemical Manufacturing Corp.
Tel
021-021-021-67601398-809-809-809 15221380277
Fax
021-57711696
Email
marketing_china@spectrumchemical.com
Country
China
ProdList
9658
Advantage
60
Wuhan Fortuna Chemical Co., Ltd
Tel
027-59207852 13308628970
Fax
QQ3130921841
Email
buy@fortunachem.com
Country
China
ProdList
2859
Advantage
58
Chengdu Ai Keda Chemical Technology Co., Ltd.
Tel
4008-755-333 18080918076
Fax
028-86757656
Email
800078821@qq.com
Country
China
ProdList
9718
Advantage
55
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9865
Advantage
52
Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611
Fax
+86 21 50676805
Country
China
ProdList
9891
Advantage
58
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22514
Advantage
55
Zouping Mingxing Chemical Co.,Ltd.
Tel
86-13605431940 13605431940
Fax
0086-0543-2240079
Email
zpmxchemical@126.com
Country
China
ProdList
1482
Advantage
62
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9978
Advantage
55
Huainan Kedi Chemical Factory
Tel
0554-2106669
Fax
0554-2666215
Email
sales1@kedichem.com
Country
China
ProdList
4924
Advantage
55
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15178
Advantage
58
Shanghai YuLue Chemical Co., Ltd.
Tel
021-60345187 13671753212
Fax
021-34702061
Email
lzz841106@aliyun.com
Country
China
ProdList
10274
Advantage
55
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939 15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
16166
Advantage
55
Hangzhou J&H Chemical Co., Ltd.
Tel
0571-+86-571-87396432
Fax
0571-87396431
Email
sales@jhechem.com
Country
China
ProdList
11662
Advantage
59
Chengdu RunZeBenTu Chemical Co., Ltd
Tel
13096311329 028-88469284 616445927
Fax
028-88469284
Email
616445927@qq.com
Country
China
ProdList
2874
Advantage
50
Credit Asia Chemical Co., Ltd.
Tel
+86 (21) 61124340
Fax
+86 (21) 6129-4103
Country
China
ProdList
9756
Advantage
58
Hubei Jusheng Technology Co.,Ltd
Tel
027-59599241 18871490274
Fax
027-59599241
Email
1400878000@qq.com
Country
China
ProdList
9958
Advantage
58
Chizhou Kailong Import and Export Trade Co., Ltd.
Tel
Fax
-
Email
xg01_gj@163.com
Country
China
ProdList
9484
Advantage
50
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
Quzhou Rundong Chemical (Technology) Co.
Tel
0570-8789886 18892685668
Fax
0570-8789985
Email
info@rundongchemical.com
Country
China
ProdList
3967
Advantage
60
Chengdu RunZeBenTu Chemical Co., Ltd
Tel
028-88469284 18000562381
Email
rzbtsj@163.com
Country
China
ProdList
9951
Advantage
56
Codow Chemical Co.,Ltd.
Tel
18620099427
Fax
+86-20-62619665
Email
amy@howeipharm.com
Country
China
ProdList
17687
Advantage
55
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
27313
Advantage
60
Shanghai QianYan Bio-technology Co., Ltd
Tel
02781293128
Email
orders@biochemsafebuy.com
Country
China
ProdList
9923
Advantage
55
Shandong Xiya Chemical Co., Ltd.
Tel
4009903999 13395398332
Fax
0539-6365991
Email
sales@xiyashiji.com
Country
China
ProdList
20806
Advantage
60
Grader reagent
Tel
18221735425
Email
sales@xinpingchem.com
Country
China
ProdList
9942
Advantage
58
Guangdong wengjiang Chemical Reagent Co., Ltd.
Tel
0751-2886750 13927877953
Fax
0751-2886750
Email
3005811397@qq.com
Country
China
ProdList
13320
Advantage
58
Taian Jiaye Biotechnology Co.Ltd
Tel
13127280945
Email
285424065@qq.com
Country
China
ProdList
9976
Advantage
55
klamar reagent
Tel
4001650900
Fax
021-64897811
Email
sales-wang@klamar-reagent.com
Country
China
ProdList
1986
Advantage
55
Greenherbs Science and Technology Development Co., Ltd.
Tel
010-61136123
Fax
+86 (10) 8857-9127
Email
pub02@greenherbs.com.cn
Country
China
ProdList
4049
Advantage
58
JinJin Le Chemical Co., Ltd
Tel
10106090
Email
jjlchem2@163.com
Country
China
ProdList
9981
Advantage
58
Shandong Ono Chemical Co., Ltd.
Tel
0539-6362799 20）
Fax
0539-6362799（To 20）
Country
China
ProdList
9998
Advantage
58
Hangzhou Molcore Biopharmatech Co.,Ltd
Tel
400-711-5280 86-571-81025280
Fax
86-571-85806285
Email
sales@molcore.com
Country
China
ProdList
9967
Advantage
58
9ding chemical ( Shanghai) Limited
Tel
021-021-52271985 17721149837
Fax
+86 (21) 52271987
Email
sales@9dingchem.com
Country
China
ProdList
19800
Advantage
60
Shanghai BaiShun Biological Technology Co., Ltd
Tel
021-37581181
Fax
021-57456066
Email
sales@chem-mall.com
Country
China
ProdList
10330
Advantage
58
Aikon International Limited
Tel
025-66113011 13155353615
Fax
(7)02557626880
Email
qzhang@aikonchem.com
Country
China
ProdList
15394
Advantage
58
Rhawn Reagent
Tel
400-400-1332688 18019345275
Fax
400-133-2688
Email
amy@rhawn.cn
Country
China
ProdList
15497
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 18016230971
Fax
021-58955996
Email
malulu@leyan.com
Country
China
ProdList
25004
Advantage
58
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400-6387771-6037 18920794737
Email
sales@heowns.com
Country
China
ProdList
23083
Advantage
60
More
Less

View Lastest Price from Sodium hydroxymethanesulphinate manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Sodium hydroxymethanesulphinate 149-44-0
Price
US $70.00/kg
Min. Order
1kg
Purity
99
Supply Ability
5000
Release date
2024-05-29
HebeiShuoshengImportandExportco.,Ltd
Product
Sodium hydroxymethanesulphinate 149-44-0
Price
US $6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000KG/Month
Release date
2024-08-05
Hebei Saisier Technology Co., LTD
Product
Sodium hydroxymethanesulphinate 149-44-0
Price
US $6.00/KG
Min. Order
1KG
Purity
More than 99%
Supply Ability
2000KG/Month
Release date
2024-04-22

149-44-0, Sodium hydroxymethanesulphinateRelated Search:

Methyl Orange Methylprednisolone Sodium lauryl sulfoacetate GLUTARALDEHYDE SODIUM BISULFITE ADDITION COMPOUND CHLOROACETALDEHYDE SODIUM BISULFITE SUCCINALDEHYDE SODIUM BISULFITE Sodium 4-chloro-1-hydroxybutanesulfonate SODIUM 2-HYDROXY-6-METHOXY-1,2,3,4-TETRAHYDRO-NAPHTHALENE-2-SULFONATE Formaldehyde sodium bisulfite ACETALDEHYDE SODIUM BISULFITE GLYOXAL SODIUM BISULFITE Sodium hydroxymethanesulphinate ACETONE SODIUM BISULFITE Sodium dithionite RONGALITE,RONGALITE C,RONGALITE(TM),RONGALITE DIHYDRATE Sodium bisulfate monohydrate Sodium bisulfate M-TOLUALDEHYDE, SODIUM BISULFITE Sodium Hydroxymethanesulfinate

  • Formaldehyde Sodium Sulfoxylate Hydroxymethanesulfinic Acid Sodium Salt Rongalite
  • aldanil
  • discolite
  • formaldehydehydrosulfite
  • formaldehydesodiumbisulfiteadduct
  • formaldehydesulfoxylicacidsodiumsalt
  • formapon
  • formopan
  • hydrolit
  • hydrosulfiteawc
  • hydroxy-methanesulfinicacimonosodiumsalt
  • Methanesulfinicacid,hydroxy-,monosodiumsalt
  • oxymethansulfinsaeurennatrium
  • rongalitc
  • Sodiumbisulfoxylateformaldehyde
  • sodiummethanalsulfoxylate
  • SodiuM hydroxyMethanesulfinate hydrate >=98.0% (RT)
  • Sodium hydroxymethanesulfinate monohydrate
  • Sodium hydroxymethanesulfinate hydrate
  • Synonym Hydroxymethanesulfinic acid sodium salt
  • sodium hydroxymethanesulphinate
  • SFS - POWDER
  • SFS - RICE GRADE
  • Sodium Formaldehyde Sulfoxylate, Chip Grade
  • Sodium Formaldehyde Sulfoxylate, Pea Grade
  • Sodium Formaldehyde Sulfoxylate, Powder Grade
  • Sodium Formaldehyde Sulfoxylate, Rice Grade
  • HydroxyMethanesulfinic acid sodiuM salt hydrate, tech 85%, cont. up to 5% sodiuM sulfite (dry wt.)
  • Hydro AWC
  • SODIUMSULPHOXYLATEFORMALDEHYDE
  • FORMOPON
  • FORMOSUL
  • Natriumhydroxymethansulfinat
  • sodium sulfoxylate formaldehyde：sodium fornaldehyde sulfoxylate
  • Hydroxymethanesulfinic acid sodium salt, RongalitTM, Sodium formaldehyde sulfoxylate hydrate
  • Hydroxymethanesulfinic acid sodium salt hydrate, 95% (dry wt.), cont, up to 5% sodium sulfite
  • Rongalit dihydrate
  • SodiuM HydroxyMethanesulfinate&nbsp
  • Sodium hydroxymethanesulfinate 95%
  • sodium hydroxymethanesulfinate CH3O3S.Na
  • sodiumoxymethanesulfinicacid
  • HYDROXYMETHANESULFINIC ACID SODIUM SALT
  • FORMALDEHYDE SODIUM SULFOXYLATE
  • RONGALITE
  • RONGALITE C
  • SODIUM SULFOXYLATE FORMALDEHYDE
  • SODIUM FORMALDEHYDESULFOXALATE
  • SODIUM FORMALDEHYDE SULFOXYLATE
  • SODIUM HYDROXYMETHANESULFINATE
  • hydroxylmethanefinic acid Na salt
  • Sodium sulfinomethanolate
  • Methanesulfinic acid, 1-hydroxy-, sodium salt (1:1)
  • Sodium Hydroxymethanesulfinate Dihydrate&gt
  • Sodium HydroxymethanesuL
  • Sodium hydroxymethanesulphinate ISO 9001：2015 REACH
  • Sodium hydroxymethanesulphinate，97%
  • Sodium Formaldehyde Sulfoxylate Hydrate (Rongalite) ExiPlus, Multi-Compendial, 98%
  • Sodium Formaldehyde Sulfoxylate Hydrate (Rongalite) pure, 98%