Sodium hydroxymethanesulphinate
- Product Name
- Sodium hydroxymethanesulphinate
- CAS No.
- 149-44-0
- Chemical Name
- Sodium hydroxymethanesulphinate
- Synonyms
- RONGALITE;SODIUM FORMALDEHYDE SULFOXYLATE;SODIUM HYDROXYMETHANESULFINATE;RONGALITE C;SODIUM FORMALDEHYDESULFOXALATE;Natriumhydroxymethansulfinat;Sodiumbisulfoxylateformaldehyde;Sodium hydroxymethanesulfinate hydrate;HYDROXYMETHANESULFINIC ACID SODIUM SALT;aldanil
- CBNumber
- CB8773339
- Molecular Formula
- CH3NaO3S
- Formula Weight
- 118.09
- MOL File
- 149-44-0.mol
Sodium hydroxymethanesulphinate Property
- Melting point:
- ~120 °C (dec.)
- Density
- 1.744[at 20℃]
- vapor pressure
- 0.003Pa at 20℃
- Flash point:
- >100℃
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- H2O: 50 mg/mL, clear, colorless
- form
- Solid
- color
- White to Off-White
- PH
- 9.5-10.5
- Water Solubility
- soluble H2O, alcohol [HAW93]
- Merck
- 14,8620
- Stability:
- Stable. Incompatible with strong oxidizing agents.
- LogP
- -3.4 at 22℃
- EPA Substance Registry System
- Sodium sulfoxylate formaldehyde (anhydrous) (149-44-0)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-68-31
- Safety Statements
- 26-36-36/37
- WGK Germany
- 1
- RTECS
- PB0380000
- TSCA
- Yes
- HS Code
- 2930909899
- Hazardous Substances Data
- 149-44-0(Hazardous Substances Data)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H341Suspected of causing genetic defects
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- R0053
- Product name
- Sodium Hydroxymethanesulfinate Dihydrate
- Purity
- >97.0%(T)
- Packaging
- 500g
- Price
- $28
- Updated
- 2022/04/27
- Product number
- A15731
- Product name
- Hydroxymethanesulfinic acid sodium salt hydrate, tech 85%, cont. up to 5% sodium sulfite (dry wt.)
- Packaging
- 500g
- Price
- $30.65
- Updated
- 2024/03/01
- Product number
- A15731
- Product name
- Hydroxymethanesulfinic acid sodium salt hydrate, tech 85%, cont. up to 5% sodium sulfite (dry wt.)
- Packaging
- 2500g
- Price
- $118.65
- Updated
- 2024/03/01
- Product number
- S634953
- Product name
- Sodium hydroxymethanesulfinate hydrate
- Packaging
- 10g
- Price
- $135
- Updated
- 2021/12/16
- Product number
- 279673
- Product name
- Sodium hydroxymethanesulfinate hydrate
- Packaging
- 250g
- Price
- $319
- Updated
- 2021/12/16
Sodium hydroxymethanesulphinate Chemical Properties,Usage,Production
Chemical Properties
white solid; used as stripping and discharge agent for textiles [HAW93]
Chemical Properties
When freshly prepared, sodium formaldehyde sulfoxylate occurs as white, odorless crystals, which quickly develop a characteristic garlic odor on standing.
Uses
Pharmaceutic aid (preservative).
Uses
Sodium Hydroxymethanesulfinate Hydrate is the hydrated version of Sodium Hydroxymethanesulfinate (S634950), which is an organic reductant that is stable in alkaline enviroments but readily decomposes in acidic medium to produce a number of products, one of them being sulfur dioxide. Sodium hydroxymethanesulfinate is also used in conjunction with substituted anilines (e.g. p-Anisidine [A673505]) to synthesize anilinomethanesulfonates.
Production Methods
Sodium formaldehyde sulfoxylate is manufactured from sodium dithionate and formaldehyde in water.
Flammability and Explosibility
Non flammable
Pharmaceutical Applications
Sodium formaldehyde sulfoxylate is a water-soluble antioxidant and is generally used as the dihydrate. It is used in the formulation of injection products at a level of up to 0.1% w/v in the final preparation administered to the patient.
Safety
The toxicological properties of sodium formaldehyde sulfoxylate
have not been fully investigated. However, it is used in the
formulation of injection products at a level to 0.1% w/v in the
final preparation administered to the patient.
Sodium formaldehyde sulfoxylate is moderately toxic by
ingestion, and when heated to decomposition it emits toxic fumes
of sulfur dioxide and sodium oxide.
LD50 (mouse, oral): 4 g/kg
LD50 (rat, IP): >2 g/kg
LD50 (rat, oral): >2 g/kg
storage
Store in well-closed, light-resistant containers at controlled room temperature (15–30℃).
Purification Methods
It crystallises from H2O as the dihydrate and decomposes at higher temperatures. Store it in a closed container in a cool place. It is insoluble in EtOH and Et2O and is a good reducing agent. [X-ray structure: Tuter J Chem Soc 3064 1955.] Note that this compound {HOCH2SO2Na} should not be confused with formaldehyde sodium bisulfite adduct {HOCH2SO3Na} from which it is prepared by reduction with Zn. [Beilstein 1 IV 3052.]
Incompatibilities
Sodium formaldehyde sulfoxylate is incompatible with strong oxidizing agents; it is decomposed by dilute acid.
Regulatory Status
Included in the FDA Inactive Ingredients Database (parenteral products up to 0.1% via the IM, IV, and SC routes). Included in the Canadian List of Acceptable Non-medicinal Ingredients.
Sodium hydroxymethanesulphinate Preparation Products And Raw materials
Raw materials
Preparation Products
Sodium hydroxymethanesulphinate Suppliers
- Tel
- --
- Fax
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- ccc@merckgroup.com
- Country
- Germany
- ProdList
- 2008
- Advantage
- 58
- Tel
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- Fax
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- info@burmester-pharma.de
- Country
- Germany
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- Tel
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- info@abcr.de
- Country
- Germany
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- Tel
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- Fax
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- sales@chemos-group.com
- Country
- Germany
- ProdList
- 6350
- Advantage
- 71
View Lastest Price from Sodium hydroxymethanesulphinate manufacturers
- Product
- Sodium hydroxymethanesulphinate 149-44-0
- Price
- US $70.00/kg
- Min. Order
- 1kg
- Purity
- 99
- Supply Ability
- 5000
- Release date
- 2024-05-29
- Product
- Sodium hydroxymethanesulphinate 149-44-0
- Price
- US $6.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 2000KG/Month
- Release date
- 2024-08-05
- Product
- Sodium hydroxymethanesulphinate 149-44-0
- Price
- US $6.00/kg
- Min. Order
- 1kg
- Purity
- More than 99%
- Supply Ability
- 2000KG/Month
- Release date
- 2024-05-27