tert-Butyl thiophen-2-ylcarbamate
Structure- Product Name
- tert-Butyl thiophen-2-ylcarbamate
- CAS No.
- 56267-50-6
- Chemical Name
- tert-Butyl thiophen-2-ylcarbamate
- Synonyms
- NSC 263609;AKOS 92405;BUTTPARK 97\57-48;2-(N-Boc-amino)thiophene;TERT-BUTYL 2-THIENYLCARBAMATE;tert-Butyl thien-2-ylcarbamate;2-Aminothiophene, 2-BOC protected;tert-Butyl thiophen-2-ylcarbaMate;TERT-BUTYL N-(2-THIENYL)CARBAMATE;2-Aminothiophene, N-BOC protected
- CBNumber
- CB8784339
- Molecular Formula
- C9H13NO2S
- Formula Weight
- 199.27
- MOL File
- 56267-50-6.mol
tert-Butyl thiophen-2-ylcarbamate Property
- Melting point:
- 151 °C
- Boiling point:
- 238.1±13.0 °C(Predicted)
- Density
- 1.186±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- form
- solid
- pka
- 13.63±0.70(Predicted)
- color
- Pale grey
- InChI
- InChI=1S/C9H13NO2S/c1-9(2,3)12-8(11)10-7-5-4-6-13-7/h4-6H,1-3H3,(H,10,11)
- InChIKey
- QTXXTRMGTVEBIN-UHFFFAOYSA-N
- SMILES
- C(OC(C)(C)C)(=O)NC1SC=CC=1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- T135640
- Product name
- tert-ButylN-(2-Thienyl)carbamate
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- 8H48-1-X1
- Product name
- 2-Aminothiophene, 2-Boc protected
- Packaging
- 1g
- Price
- $40
- Updated
- 2021/12/16
- Product number
- FB144286
- Product name
- tert-Butyl thiophen-2-ylcarbamate
- Packaging
- 100mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- 081321
- Product name
- tert-Butyl thien-2-ylcarbamate
- Purity
- 97%
- Packaging
- 1g
- Price
- $92
- Updated
- 2021/12/16
- Product number
- FB144286
- Product name
- tert-Butyl thiophen-2-ylcarbamate
- Packaging
- 250mg
- Price
- $100
- Updated
- 2021/12/16
tert-Butyl thiophen-2-ylcarbamate Chemical Properties,Usage,Production
Structure
Tert-butyl thiophen-2-ylcarbamate, C9H13NO2S, is a precursor in synthesising diimine ligands suitable for metal complex formation. This compound exhibits intramolecular methyl C7—H···O1 and C8—H···O1 interactions [2.938 (4) and 3.109 (4), respectively] in addition to bulky tert -butyl groups. These two features in tandem allow the packing in the crystal to be nearly perpendicular [the angle between adjacent thiophene rings = 74.83 (7)°]. An intermolecular N1—H···O1i hydrogen bond gives a one-dimensional chain which extends along [0 0 1].
Chemical Properties
White to off-white crystalline powder
Synthesis
To a solution of thiophenecarboxylic acid (0.5 g, 3.90 mmol) in tBuOH (10 ml) was added Et3N (0.571 ml, 4.10 mmol) and DPPA (0.883 ml, 4.10 mmol). The solution was heated at 90 °C for 4 hours. The reaction mixture was cooled to RT, and the solvent was removed from the vacuum. The residue was treated with benzene, and the solution was washed with 5 per cent citric acid and NaHCO3. Solid was filtered off, and the filtrate was washed with brine. The organic layer was dried (MgSO4), concentrated in vacuo and the residue was purified by silica gel column chromatography (EtOAc/hexanes) to obtain tert-butyl thiophen-2-ylcarbamate (0.39 g, 50percent yield). 1H NMR (400 MHz, DMSO-d6): δ 10.4 (brs, 1H), 6.84 (dd, J = 1.6, and 5.2 Hz, 1H), 6.75 (dd, J = 4.0, and 5.6 Hz, 1H), 6.48 (dd, J= 1.6, and 4.0 Hz, 2H), 1.45 (s, 9H); MS (ESI) m/z: 222.0 (M+22+H+).
tert-Butyl thiophen-2-ylcarbamate Preparation Products And Raw materials
Raw materials
Preparation Products
tert-Butyl thiophen-2-ylcarbamate Suppliers
- Tel
- --
- Fax
- --
- sales@chemos-group.com
- Country
- Germany
- ProdList
- 6350
- Advantage
- 71
- Tel
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- Fax
- --
- akos@akosgmbh.de
- Country
- Germany
- ProdList
- 6717
- Advantage
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View Lastest Price from tert-Butyl thiophen-2-ylcarbamate manufacturers
- Product
- TERT-BUTYL N-(2-THIENYL)CARBAMATE 56267-50-6
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 1000KGS
- Release date
- 2019-12-19