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PAGOCLONE

Product Name
PAGOCLONE
CAS No.
133737-32-3
Chemical Name
PAGOCLONE
Synonyms
Ip 456;CI-1043;RP 59037;AGOCLONE;Rp 62955;(+)-Pagoclone;(+)-RP-59037; IP-456; RP-62955; CI-1043;2-(7-Chloro-1,8-naphthyridin-2-yl)-3-(5-Methyl-2-oxohexyl)isoindolin-1-one;2-(7-Chloro-1,8-naphthyridin-2-yl)-3-(5-methyl-2-oxohexyl)-1-isoindolinone;2-(7-chloro-1,8-naphthyridin-2-yl)-3-(5-methyl-2-oxohexyl)-3H-isoindol-1-one
CBNumber
CB8839954
Molecular Formula
C23H22ClN3O2
Formula Weight
407.89
MOL File
133737-32-3.mol
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PAGOCLONE Property

Boiling point:
582.1±50.0 °C(Predicted)
Density 
1.273±0.06 g/cm3(Predicted)
pka
1.62±0.30(Predicted)
form 
Solid
color 
White to off-white
InChI
InChI=1S/C23H22ClN3O2/c1-14(2)7-10-16(28)13-19-17-5-3-4-6-18(17)23(29)27(19)21-12-9-15-8-11-20(24)25-22(15)26-21/h3-6,8-9,11-12,14,19H,7,10,13H2,1-2H3
InChIKey
HIUPRQPBWVEQJJ-UHFFFAOYSA-N
SMILES
C1(=O)C2=C(C=CC=C2)C(CC(=O)CCC(C)C)N1C1=CC=C2C(=N1)N=C(Cl)C=C2
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
BP177437
Product name
Pagoclone NEW
Packaging
25mg
Price
$198.75
Updated
2021/12/16
Biosynth Carbosynth
Product number
BP177437
Product name
Pagoclone NEW
Packaging
50mg
Price
$265
Updated
2021/12/16
Biosynth Carbosynth
Product number
BP177437
Product name
Pagoclone NEW
Packaging
100mg
Price
$360
Updated
2021/12/16
Biosynth Carbosynth
Product number
BP177437
Product name
Pagoclone NEW
Packaging
250mg
Price
$475
Updated
2021/12/16
Biosynth Carbosynth
Product number
BP177437
Product name
Pagoclone NEW
Packaging
500mg
Price
$650
Updated
2021/12/16
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PAGOCLONE Chemical Properties,Usage,Production

Description

Pagoclone is a drug that belongs to the class of cyclopyrrolones. It binds to the benzodiazepine binding site on GABAA receptors and acts as a negative allosteric modulator, thereby enhancing the inhibitory effects of GABA and reducing neuronal excitability.

Uses

Anti-anxiety agent.

Application

Pagoclone has been shown to have anti-inflammatory properties in an animal model of inflammatory bowel disease and may be useful for the treatment of this condition.

brand name

Bextra (Interneuron).

PAGOCLONE Preparation Products And Raw materials

Raw materials

Preparation Products

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PAGOCLONE Suppliers

BOC Sciences
Tel
+1-631-485-4226
Fax
1-631-614-7828
Email
inquiry@bocsci.com
Country
United States
ProdList
19553
Advantage
58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38632
Advantage
58
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
Waterstone Technology, LLC
Tel
--
Fax
--
Email
sales@waterstonetech.com
Country
United States
ProdList
6786
Advantage
30
AlliChem, LLC
Tel
--
Fax
--
Email
sales@allichemllc.com
Country
United States
ProdList
6516
Advantage
60
2A PharmaChem USA
Tel
--
Fax
--
Email
sales@2apharmachem.com
Country
United States
ProdList
6137
Advantage
39
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6718
Advantage
47
ChemPacific Corporation
Tel
--
Fax
--
Email
sales@chempacific.com
Country
United States
ProdList
6891
Advantage
51
Synergetica, Inc.
Tel
--
Fax
--
Email
lee.dewitt@synergeticainc.com
Country
United States
ProdList
100
Advantage
51
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View Lastest Price from PAGOCLONE manufacturers

Dorne Chemical Technology co. LTD
Product
Pagoclone 133737-32-3
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
100kg
Release date
2024-03-26
airuikechemical co., ltd.
Product
PAGOCLONE 133737-32-3
Price
US $0.00-0.00/Kg
Min. Order
1Kg
Purity
99.9%
Supply Ability
20 tons
Release date
2024-04-07
Shandong Hanjiang Chemical Co., Ltd
Product
PAGOCLONE 133737-32-3
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10T
Release date
2024-01-25

133737-32-3, PAGOCLONERelated Search:


  • 2-(7-Chloro-1,8-naphthyridin-2-yl)-3-(5-methyl-2-oxohexyl)-1-isoindolinone
  • RP 59037
  • Ip 456
  • Rp 62955
  • 2-(7-Chloro-1,8-naphthyridin-2-yl)-3-(5-Methyl-2-oxohexyl)isoindolin-1-one
  • (+)-RP-59037; IP-456; RP-62955; CI-1043
  • CI-1043
  • AGOCLONE
  • inhibit,GABA Receptor,γ-Aminobutyric acid Receptor,Gamma-aminobutyric acid Receptor,IP 456,RP 62955,RP62955,Pagoclone,Inhibitor
  • (+)-Pagoclone
  • 2-(7-chloro-1,8-naphthyridin-2-yl)-3-(5-methyl-2-oxohexyl)-3H-isoindol-1-one
  • 133737-32-3
  • C23H22ClN3O2