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PLECONARIL

Product Name
PLECONARIL
CAS No.
153168-05-9
Chemical Name
PLECONARIL
Synonyms
Picovir;VP 63843;Rimiducid;WIN 63843;PLECONARIL;Pleconarilis;Pleconaril-d4;PLECONARIL USP/EP/BP;Pleconaril VP-63843 Win-63843;3-[3,5-DiMethyl-4-[3-(3-Methyl-5-isoxazolyl)propoxy]phenyl]-5-(trifluoroMethyl)-
CBNumber
CB8840318
Molecular Formula
C18H18F3N3O3
Formula Weight
381.35
MOL File
153168-05-9.mol
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PLECONARIL Property

Melting point:
61-62°
Boiling point:
481.2±55.0 °C(Predicted)
Density 
1.271
storage temp. 
room temp
solubility 
DMSO: ≥10mg/mL (warmed)
pka
-1.33±0.10(Predicted)
form 
powder
color 
white to beige
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Safety

Hazard Codes 
T
Risk Statements 
25
Safety Statements 
45
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H413May cause long lasting harmful effects to aquatic life

Precautionary statements

P273Avoid release to the environment.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0307
Product name
Pleconaril
Purity
≥98% (HPLC)
Packaging
10mg
Price
$215
Updated
2024/03/01
Sigma-Aldrich
Product number
SML0307
Product name
Pleconaril
Purity
≥98% (HPLC)
Packaging
50mg
Price
$316
Updated
2024/03/01
Cayman Chemical
Product number
28461
Product name
Pleconaril
Packaging
10mg
Price
$121
Updated
2024/03/01
Cayman Chemical
Product number
28461
Product name
Pleconaril
Packaging
100mg
Price
$662
Updated
2024/03/01
Cayman Chemical
Product number
28461
Product name
Pleconaril
Packaging
25mg
Price
$241
Updated
2024/03/01
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PLECONARIL Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

Pleconaril has been used as a control or reference compound to assess the antiviral activities of the benzothiophene and other heteroaromatic derivatives against hRV-B14, hRV-A21 and hRV-A71.

Uses

Picornavirus replication inhibitor. Antiviral.

General Description

Pleconaril is a drug, that has antiviral activity.

Pharmaceutical Applications

An oxadiazole active against most enteroviruses and rhinoviruses. It binds to the hydrophobic pocket of the virus capsid protein VP1, inducing conformational changes that lead to altered receptor binding and viral uncoating. Concerns over safety and efficacy have constrained development of the drug.

Biochem/physiol Actions

Pleconaril is an effective drug against enteroviral infections. It can be used to treat chronic meningoencephalitis caused by echo virus 6.This can block viral replication by blocking the viral uncoating process and viral attachment to host cell receptors.

PLECONARIL Preparation Products And Raw materials

Raw materials

Preparation Products

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PLECONARIL Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
LGM Pharma
Tel
1-(800)-881-8210
Fax
615-250-9817
Email
inquiries@lgmpharma.com
Country
United States
ProdList
2123
Advantage
70
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4861
Advantage
58
Shanghai Hekang Biotechnology Co., Ltd.
Tel
18939837085
Fax
2880152141(QQ)
Email
youchemicals@gmail.com
Country
China
ProdList
1830
Advantage
55
Porse Fine Chemical Co.,LTD
Tel
20-66003216 18666003216
Fax
+86-20-28069063
Email
info@porsefinechemical.com
Country
China
ProdList
2319
Advantage
62
Hangzhou J&H Chemical Co., Ltd.
Tel
0571-+86-571-87396432
Fax
0571-87396431
Email
sales@jhechem.com
Country
China
ProdList
11487
Advantage
59
Chizhou Kailong Import and Export Trade Co., Ltd.
Tel
Fax
-
Email
xg01_gj@163.com
Country
China
ProdList
9484
Advantage
50
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
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View Lastest Price from PLECONARIL manufacturers

Dideu Industries Group Limited
Product
PLECONARIL 153168-05-9
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons Min
Release date
2021-07-15
Career Henan Chemical Co
Product
PLECONARIL 153168-05-9
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
kg/T
Release date
2019-12-18

153168-05-9, PLECONARILRelated Search:


  • PLECONARIL
  • WIN 63843
  • 3-[3,5-Dimethyl-4-[3-(3-methyl-5-isoxazolyl)propoxy]phenyl]-5-(trifluoromethyl)-1,2,4-oxadiazole
  • Picovir
  • 3-[3,5-DiMethyl-4-[3-(3-Methyl-5-isoxazolyl)propoxy]phenyl]-5-(trifluoroMethyl)-
  • 1,2,4-Oxadiazole,3-[3,5-diMethyl-4-[3-(3-Methyl-5-isoxazolyl)propoxy]phenyl]-5-(trifluoroMethyl)-
  • VP 63843
  • 3-(3,5-dimethyl-4-(3-(3-methylisoxazol-5-yl)propoxy)phenyl)-5-(trifluoromethyl)-1,2,4-oxadiazole
  • Rimiducid
  • Pleconarilis
  • 3-{3,5-dimethyl-4-[3-(3-methyl-1,2-oxazol-5-yl)propoxy]phenyl}-5-(trifluoromethyl)-1,2,4-oxadiazole
  • Pleconaril-d4
  • PLECONARIL USP/EP/BP
  • Pleconaril VP-63843 Win-63843
  • 153168-05-9
  • Anti-virals
  • Heterocycles
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • API