PLECONARIL

Product Name: PLECONARIL
CAS No.: 153168-05-9
Chemical Name: PLECONARIL
Synonyms: Picovir;VP 63843;Rimiducid;WIN 63843;PLECONARIL;Pleconarilis;Pleconaril-d4;PLECONARIL USP/EP/BP;Pleconaril VP-63843 Win-63843;3-[3,5-DiMethyl-4-[3-(3-Methyl-5-isoxazolyl)propoxy]phenyl]-5-(trifluoroMethyl)-
CBNumber: CB8840318
Molecular Formula: C18H18F3N3O3
Formula Weight: 381.35
MOL File: 153168-05-9.mol

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PLECONARIL Property

Melting point:: 61-62°
Boiling point:: 481.2±55.0 °C(Predicted)
Density: 1.271
storage temp.: room temp
solubility: DMSO: ≥10mg/mL (warmed)
pka: -1.33±0.10(Predicted)
form: powder
color: white to beige

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Safety

Hazard Codes: T
Risk Statements: 25
Safety Statements: 45
RIDADR: UN 2811 6.1 / PGIII
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H413May cause long lasting harmful effects to aquatic life

Precautionary statements

P273Avoid release to the environment.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0307
Product name: Pleconaril
Purity: ≥98% (HPLC)
Packaging: 10mg
Price: $215
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0307
Product name: Pleconaril
Purity: ≥98% (HPLC)
Packaging: 50mg
Price: $316
Updated: 2024/03/01

Cayman Chemical

Product number: 28461
Product name: Pleconaril
Packaging: 10mg
Price: $121
Updated: 2024/03/01

Cayman Chemical

Product number: 28461
Product name: Pleconaril
Packaging: 100mg
Price: $662
Updated: 2024/03/01

Cayman Chemical

Product number: 28461
Product name: Pleconaril
Packaging: 25mg
Price: $241
Updated: 2024/03/01

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PLECONARIL Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

Pleconaril has been used as a control or reference compound to assess the antiviral activities of the benzothiophene and other heteroaromatic derivatives against hRV-B14, hRV-A21 and hRV-A71.

Uses

Picornavirus replication inhibitor. Antiviral.

General Description

Pleconaril is a drug, that has antiviral activity.

Pharmaceutical Applications

An oxadiazole active against most enteroviruses and rhinoviruses. It binds to the hydrophobic pocket of the virus capsid protein VP1, inducing conformational changes that lead to altered receptor binding and viral uncoating. Concerns over safety and efficacy have constrained development of the drug.

Biochem/physiol Actions

Pleconaril is an effective drug against enteroviral infections. It can be used to treat chronic meningoencephalitis caused by echo virus 6.This can block viral replication by blocking the viral uncoating process and viral attachment to host cell receptors.

PLECONARIL Preparation Products And Raw materials

Raw materials

Preparation Products

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PLECONARIL Suppliers

Canada 1 China 81 Europe 2 Germany 1 India 1 United States 15 Global 101

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View Lastest Price from PLECONARIL manufacturers

Dideu Industries Group Limited

Product: PLECONARIL 153168-05-9
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons Min
Release date: 2021-07-15

Career Henan Chemical Co

Product: PLECONARIL 153168-05-9
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: kg/T
Release date: 2019-12-18

153168-05-9, PLECONARILRelated Search:

3-METHYL-5-ISOXAZOLEPROPANOL PLECONARIL

PLECONARIL

WIN 63843

3-[3,5-Dimethyl-4-[3-(3-methyl-5-isoxazolyl)propoxy]phenyl]-5-(trifluoromethyl)-1,2,4-oxadiazole

Picovir

3-[3,5-DiMethyl-4-[3-(3-Methyl-5-isoxazolyl)propoxy]phenyl]-5-(trifluoroMethyl)-

1,2,4-Oxadiazole,3-[3,5-diMethyl-4-[3-(3-Methyl-5-isoxazolyl)propoxy]phenyl]-5-(trifluoroMethyl)-

VP 63843

3-(3,5-dimethyl-4-(3-(3-methylisoxazol-5-yl)propoxy)phenyl)-5-(trifluoromethyl)-1,2,4-oxadiazole

Rimiducid

Pleconarilis

3-{3,5-dimethyl-4-[3-(3-methyl-1,2-oxazol-5-yl)propoxy]phenyl}-5-(trifluoromethyl)-1,2,4-oxadiazole

Pleconaril-d4

PLECONARIL USP/EP/BP

Pleconaril VP-63843 Win-63843

153168-05-9

Anti-virals

Heterocycles

Inhibitors

Intermediates & Fine Chemicals

Pharmaceuticals

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