ChemicalBook > CAS DataBase List > PLECONARIL
PLECONARIL
- Product Name
- PLECONARIL
- CAS No.
- 153168-05-9
- Chemical Name
- PLECONARIL
- Synonyms
- Picovir;VP 63843;Rimiducid;WIN 63843;PLECONARIL;Pleconarilis;Pleconaril-d4;PLECONARIL USP/EP/BP;Pleconaril VP-63843 Win-63843;3-[3,5-DiMethyl-4-[3-(3-Methyl-5-isoxazolyl)propoxy]phenyl]-5-(trifluoroMethyl)-
- CBNumber
- CB8840318
- Molecular Formula
- C18H18F3N3O3
- Formula Weight
- 381.35
- MOL File
- 153168-05-9.mol
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PLECONARIL Property
- Melting point:
- 61-62°
- Boiling point:
- 481.2±55.0 °C(Predicted)
- Density
- 1.271
- storage temp.
- room temp
- solubility
- DMSO: ≥10mg/mL (warmed)
- pka
- -1.33±0.10(Predicted)
- form
- powder
- color
- white to beige
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- SML0307
- Product name
- Pleconaril
- Purity
- ≥98% (HPLC)
- Packaging
- 10mg
- Price
- $215
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- SML0307
- Product name
- Pleconaril
- Purity
- ≥98% (HPLC)
- Packaging
- 50mg
- Price
- $316
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 28461
- Product name
- Pleconaril
- Packaging
- 10mg
- Price
- $121
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 28461
- Product name
- Pleconaril
- Packaging
- 100mg
- Price
- $662
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 28461
- Product name
- Pleconaril
- Packaging
- 25mg
- Price
- $241
- Updated
- 2024/03/01
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PLECONARIL Chemical Properties,Usage,Production
Chemical Properties
Off-White Solid
Uses
Pleconaril has been used as a control or reference compound to assess the antiviral activities of the benzothiophene and other heteroaromatic derivatives against hRV-B14, hRV-A21 and hRV-A71.
Uses
Picornavirus replication inhibitor. Antiviral.
General Description
Pleconaril is a drug, that has antiviral activity.
Pharmaceutical Applications
An oxadiazole active against most enteroviruses and rhinoviruses. It binds to the hydrophobic pocket of the virus capsid protein VP1, inducing conformational changes that lead to altered receptor binding and viral uncoating. Concerns over safety and efficacy have constrained development of the drug.
Biochem/physiol Actions
Pleconaril is an effective drug against enteroviral infections. It can be used to treat chronic meningoencephalitis caused by echo virus 6.This can block viral replication by blocking the viral uncoating process and viral attachment to host cell receptors.
PLECONARIL Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from PLECONARIL manufacturers
Dideu Industries Group Limited
- Product
- PLECONARIL 153168-05-9
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-07-15
Career Henan Chemical Co
- Product
- PLECONARIL 153168-05-9
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- kg/T
- Release date
- 2019-12-18