ChemicalBook > CAS DataBase List > 7-BROMO-2,4-DIAMINOQUINAZOLINE

7-BROMO-2,4-DIAMINOQUINAZOLINE

Product Name
7-BROMO-2,4-DIAMINOQUINAZOLINE
CAS No.
137553-43-6
Chemical Name
7-BROMO-2,4-DIAMINOQUINAZOLINE
Synonyms
DHFR-IN-3;Aids007525;Aids-007525;DHFR-IN-3, 10 mM in DMSO;2,4-DiaMino-7-broMoquinazoline;7-BROMO-2,4-DIAMINOQUINAZOLINE;7-BROMO-QUINAZOLINE-2,4-DIAMINE;2,4-Quinazolinediamine, 7-bromo-;Inhibitor,inhibit,Parasite,Antifolate,7 Bromo 2,4 diaminoquinazoline,dihydrofolate reductase,DHFR,7Bromo2,4diaminoquinazoline
CBNumber
CB8843399
Molecular Formula
C8H7BrN4
Formula Weight
239.07
MOL File
137553-43-6.mol
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7-BROMO-2,4-DIAMINOQUINAZOLINE Property

Boiling point:
509.4±58.0 °C(Predicted)
Density 
1.828±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
form 
Solid
pka
7.94±0.70(Predicted)
color 
White to off-white
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Safety

HS Code 
2933499090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

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N-Bromosuccinimide Price

TRC
Product number
B129555
Product name
7-Bromoquinazoline-2,4-diamine
Packaging
500mg
Price
$175
Updated
2021/12/16
SynQuest Laboratories
Product number
3H30-9-07
Product name
7-Bromo-2,4-diaminoquinazoline
Purity
95%
Packaging
250mg
Price
$55
Updated
2021/12/16
Matrix Scientific
Product number
072470
Product name
7-Bromo-2,4-diaminoquinazoline
Purity
95+%
Packaging
500mg
Price
$115
Updated
2021/12/16
SynQuest Laboratories
Product number
3H30-9-07
Product name
7-Bromo-2,4-diaminoquinazoline
Purity
95%
Packaging
1g
Price
$124
Updated
2021/12/16
BroadPharm
Product number
BP-11975
Product name
7-bromoquinazoline-2,4-diamine
Packaging
500mg
Price
$155
Updated
2021/12/16
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7-BROMO-2,4-DIAMINOQUINAZOLINE Chemical Properties,Usage,Production

Uses

DHFR-IN-3 is a dihydrofolate reductase (DHFR) inhibitor with the IC50 values of 19 μM and 12 μM in rat liver and P. carinii DHFR, respectively[1].

References

[1] A Rosowsky, et al. Structure-activity and structure-selectivity studies on diaminoquinazolines and other inhibitors of Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase. Antimicrob Agents Chemother. 1995 Jan;39(1):79-86. DOI:10.1128/AAC.39.1.79

7-BROMO-2,4-DIAMINOQUINAZOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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7-BROMO-2,4-DIAMINOQUINAZOLINE Suppliers

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View Lastest Price from 7-BROMO-2,4-DIAMINOQUINAZOLINE manufacturers

Honest Joy Holdings Limited
Product
7-Bromo-2,4-diaminoquinazoline 137553-43-6
Price
US $0.00/KG
Min. Order
1KG
Purity
99.2%
Supply Ability
100 tons
Release date
2022-01-26

137553-43-6, 7-BROMO-2,4-DIAMINOQUINAZOLINERelated Search:


  • 7-BROMO-QUINAZOLINE-2,4-DIAMINE
  • 7-BROMO-2,4-DIAMINOQUINAZOLINE
  • 2,4-Quinazolinediamine, 7-bromo-
  • Aids007525
  • Aids-007525
  • 2,4-DiaMino-7-broMoquinazoline
  • DHFR-IN-3
  • Inhibitor,inhibit,Parasite,Antifolate,7 Bromo 2,4 diaminoquinazoline,dihydrofolate reductase,DHFR,7Bromo2,4diaminoquinazoline
  • DHFR-IN-3, 10 mM in DMSO
  • 137553-43-6