ChemicalBook > CAS DataBase List > KETOCONAZOLE INTERMEDIATE

KETOCONAZOLE INTERMEDIATE

Product Name
KETOCONAZOLE INTERMEDIATE
CAS No.
61397-58-8
Chemical Name
KETOCONAZOLE INTERMEDIATE
Synonyms
Cis lmidazole Alcohol;Ketoconazole Impurity 8;Ketoconazole Impurity 21;KETOCONAZOLE INTERMEDIATE;Ketoconazole Hydroxymethyl Impurity;rac-Ketoconazole Hydroxymethyl Impurity;Ketoconazole Impurity 13 (and enantiomer);CIS-2-(2,4-DICHLOROPHENYL)-2- (1H-IMIDAZOL-1-YLMETHYL)-1,3;Ketoconazole Impurity 8 (rac-Ketoconazole Hydroxymethyl Impurity);cis-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolane-4-methanol
CBNumber
CB8848703
Molecular Formula
C14H14Cl2N2O3
Formula Weight
329.18
MOL File
61397-58-8.mol
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KETOCONAZOLE INTERMEDIATE Property

Melting point:
99-101 °C
Boiling point:
529.1±50.0 °C(Predicted)
Density 
1.48±0.1 g/cm3(Predicted)
storage temp. 
Refrigerator
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
14.20±0.10(Predicted)
color 
White
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
D435930
Product name
cis-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolane-4-methanol
Packaging
250mg
Price
$185
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
56880
Product name
cis-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolane-4-methanol
Packaging
250mg
Price
$650
Updated
2021/12/16
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KETOCONAZOLE INTERMEDIATE Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

cis-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolane-4-methanol is a Ketoconazole (K186000) fragment that may have modulatory activity on the large conductance calcium-activated potassium channel (BKCa).

KETOCONAZOLE INTERMEDIATE Preparation Products And Raw materials

Raw materials

Preparation Products

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61397-58-8, KETOCONAZOLE INTERMEDIATERelated Search:

Ketoconazole cis-[2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl-4-methylbenzenesulphonate 2,3-Dehydro Ketoconazole rac-trans-Ketoconazole Ketoconazole Impurity 4 Ketoconazole Impurity 15 2,2,2-trideuterio-1-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]ethanone Ketoconazole Impurity 1 KetoconazoleN-Oxide Ketoconazole Impurity 9 (Ketoconazole Hydroxymethyl Impurity) Ketoconazole Impurity 6 Ketoconazole Impurity 3 cis-1-[4-[[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine Ketoconazole Impurity 2 2-(2,4-DICHLOROPHENYL)-2-(1H-IMIDAZOL-1-YL METHYL)-1,3-DIOXOLANE-4-METHANOL 4-(1-Acetylpiperazin-4-yl)phenol Ketoconazole Impurity 11 2',4'-Dichloroacetophenone

  • KETOCONAZOLE INTERMEDIATE
  • cis-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolane-4-methanol
  • [(R)-2-(2,4-DICHLORO-PHENYL)-2-IMIDAZOL-1-YLMETHYL-[1,3]DIOXOLAN-4-YL]-METHANOL
  • CIS-2-(2,4-DICHLOROPHENYL)-2- (1H-IMIDAZOL-1-YLMETHYL)-1,3
  • rel-2α*-(1H-Imidazole-1-ylmethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolane-4α*-methanol
  • (2R,4S)-rel-2-(2,4-dichlorophenyl)-2-(1H-iMidazol-1-ylMethyl)-1,3-dioxolane-4-Methanol
  • rac-Ketoconazole Hydroxymethyl Impurity
  • Ketoconazole Impurity 8
  • Ketoconazole Impurity 8 (rac-Ketoconazole Hydroxymethyl Impurity)
  • Ketoconazole Hydroxymethyl Impurity
  • 1,3-Dioxolane-4-Methanol, 2-(2,4-dichlorophenyl)-2-(1H-iMidazol-1-ylMethyl)-, cis-
  • 1,3-Dioxolane-4-methanol, 2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-, (2R,4S)-rel-
  • ((2R,4S)-2-((1H-imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methanol
  • Ketoconazole Impurity 21
  • Ketoconazole Impurity 13 (and enantiomer)
  • Cis lmidazole Alcohol
  • 61397-58-8
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