4-Methylumbelliferyl-beta-D-glucopyranoside

Product Name: 4-Methylumbelliferyl-beta-D-glucopyranoside
CAS No.: 18997-57-4
Chemical Name: 4-Methylumbelliferyl-beta-D-glucopyranoside
Synonyms: MUD;MUG;MU-Glu;MUGGAL;MU-GAL;7-(B2;4-MU-GLU;GLC1-B-4MU;MUGLUCOSIDE;4-MU-β-Gluc
CBNumber: CB8853266
Molecular Formula: C16H18O8
Formula Weight: 338.31
MOL File: 18997-57-4.mol

More

Less

4-Methylumbelliferyl-beta-D-glucopyranoside Property

Melting point:: 258-263 °C (dec.)
Boiling point:: 394.46°C (rough estimate)
Density: 1.522
refractive index: 1.4430 (estimate)
storage temp.: Sealed in dry,Store in freezer, under -20°C
solubility: DMF: 5 mg/ml; DMSO: 50 mg/ml
pka: 12.73±0.70(Predicted)
form: Powder
color: White to off-white
Water Solubility: Soluble in DMF or water
λmax: 320nm(Buffer)(lit.)
BRN: 94672
CAS DataBase Reference: 18997-57-4(CAS DataBase Reference)

More

Less

Safety

Hazard Codes: T+
Risk Statements: 26/27/28
Safety Statements: 22-24/25
WGK Germany: 3
F: 3-10-21
HS Code: 29389090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: M3633
Product name: 4-Methylumbelliferyl β-D-glucopyranoside
Purity: β-glucosidase substrate
Packaging: 1g
Price: $485
Updated: 2024/03/01

Sigma-Aldrich

Product number: M3633
Product name: 4-Methylumbelliferyl β-D-glucopyranoside
Purity: β-glucosidase substrate
Packaging: 5g
Price: $1870
Updated: 2024/03/01

TCI Chemical

Product number: M3022
Product name: 4-Methylumbelliferyl β-D-Glucopyranoside
Purity: >98.0%(HPLC)
Packaging: 250mg
Price: $26
Updated: 2024/03/01

TCI Chemical

Product number: M3022
Product name: 4-Methylumbelliferyl β-D-Glucopyranoside
Purity: >98.0%(HPLC)
Packaging: 1g
Price: $73
Updated: 2024/03/01

Alfa Aesar

Product number: J66630
Product name: 4-Methylumbelliferyl beta-D-glucopyranoside, 99%
Packaging: 1g
Price: $135
Updated: 2024/03/01

More

Less

4-Methylumbelliferyl-beta-D-glucopyranoside Chemical Properties,Usage,Production

Description

4-Methylumbelliferyl-β-D-Glucopyranoside (4-MUG) is a fluorogenic substrate of β-glucosidase and β-glucocerebrosidase (also known as glucosylceramidase). In addition to its use in characterizing novel β-glucosidases, 4-MUG is used in assays to evaluate deficiency in β- glucocerebrosidase activity related to Gaucher disease. Hydrolysis of 4-MUG releases the fluorescent product 4-MU, which has an emission maximum at 445-454 nm. The excitation maximum for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively.

Chemical Properties

White Powder

Uses

A fluorogenic substrate in the assay of ?-glucosidase. Fluorescence: max. Abs. 316nm; max. Em. 372nm; e x 10-3: 15

Uses

A fluorogenic substrate in the assay of ?-glucosidase.Fluorescence: max. Abs. 316nm; max. Em. 372nm; e x 10-3: 15

Uses

4-Methylumbelliferyl β-D-glucopyranoside has been used as substrate:

in glucosylceramidase β enzyme activity assay in lysosome-enriched fractions from primary hippocampal neurons
in β-glucosidase assay during yeast fermentation
to assay glucocerebrosidase 1 (GBA1)-related glucosidase activity in macrophage cell line (RAW)

Definition

ChEBI: A beta-D-glucoside having a 4-methylumbelliferyl substituent at the anomeric position.

Biochem/physiol Actions

4-Methylumbelliferyl β-D-glucopyranoside is a synthetic enzymatic substrate for glycosidase. It has been used as substrate for the β- glucosidase from enterococci.

Purification Methods

4-Methylumbellifer-7-yl--Dglucopyranoside crystallises as the half hydrate from hot H2O. [Constantzas & Kocourek Collect Czech Chem Commun 24 1099 1959, De Re et al. Ann Chim (Rome) 4 9 2089 1959, Courtin-Duchateau & Veyrière Carbohydr Research 65 23, 29 1978, Beilstein 18 III/IV 5152, 8 IV 433, 18/7 V 616.]

4-Methylumbelliferyl-beta-D-glucopyranoside Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

4-Methylumbelliferyl-beta-D-glucopyranoside Suppliers

Americas 1 Austria 1 Belgium 1 Canada 1 China 164 Europe 3 France 1 Germany 6 India 11 Italy 1 Japan 4 Poland 1 Switzerland 4 United Kingdom 16 United States 36 Global 251

TCI AMERICA

Tel: 800-4238616
Fax: +1-888-520-1075 / +1-503-283-1987
Email: sales@tciamerica.com
Country: Americas
ProdList: 23653
Advantage: 75

More

Less

View Lastest Price from 4-Methylumbelliferyl-beta-D-glucopyranoside manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 4-Methylumbelliferyl-beta-D-glucopyranoside 18997-57-4
Price: US $0.00/G
Min. Order: 10G
Purity: 98%min
Supply Ability: 30kg/month
Release date: 2023-02-15

Zhuozhou Wenxi import and Export Co., Ltd

Product: 4-Methylumbelliferyl-beta-D-glucopyranoside 18997-57-4
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-27

Career Henan Chemical Co

Product: 4-Methylumbelliferyl-beta-D-glucopyranoside 18997-57-4
Price: US $1.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 100KG
Release date: 2018-12-18

18997-57-4, 4-Methylumbelliferyl-beta-D-glucopyranosideRelated Search:

4-METHYLUMBELLIFERYL-BETA-D-GLUCO-PYRANOSIDE FOR FLUORESCENCE 99+%

4-METHYLUMBELLIFERYL BETA-D-GLUCOSIDE CRYSTALLINE

4-METHYLUMBELLIFERYL-b-D-GLUCOPYRANOSIDE extrapure

4-methylumberiferryl-beta-D-glucopyranoside

4-Methylumbelliferryl-β-D-glucoside

7-(β-D-Glucopyranosyloxy)-4-methyl-2H-1-benzopyran-2-one

7-(β-D-Glucopyranosyloxy)-4-methylcoumarin

4-Methylumbelliferyl-beta-D-glucopyranoside,99%

4-Methylumbellifery-β-D-glucopyranoside

4-Methylumbelliferyl β-D-glucopyranoside ,98%

MU-Glu

3-MethyluMbelliferyl β-D-glucopyranoside

4-MethyluMbelliferyl-beta-D-glucopyranoside, 99% 500MG

4-MethyluMbelliferyl Glucopyranoside

4-Methylumbelliferyl β-D-glucopyranosid

4-Methylumbelliferyl-beta-D-glucoside *CAS 18997-57-4*

4-Methylumbelliferyl β-D-glucopyranoside,MUD

4-Methyl-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxyMethyl)tetrahydro-2H-pyran-2-yl)oxy)-2H-chroMen-2-one

4-methyl-7-[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-2-oxanyl]oxy]-1-benzopyran-2-one

4-methylumbelliferylglucoside

7-(beta-d-glucopyranosyloxy)-4-methyl-2h-1-benzopyran-2-on

MUD

MUGGAL

MUGLUCOSIDE

MUG

MU-GAL

MUGALACTOSIDE

METHYLUMBELLIFERYL-B-D-GALACTOPYRANOSIDE, 4-

METHYLUMBELLIFERYL-B-D-GLUCOPYRANOSIDE, 4-

GLC1-B-4MU

4-METHYLUMBELLIFERYL BETA-D-GLUCOSIDE

4-METHYLUMBELLIFERYL B-D-GALACTOPYRANOSIDE

4-METHYLUMBELLIFERYL-B-D-GALACTOSIDE

4-MU-BETA-D-GLC

4-MU-BETA-D-GAL

7-HYDROXY-4-METHYLCUMARIN-BETA-D-GALACTOPYRANOSID

7-HYDROXY-4-METHYLCUMARIN-BETA-D-GLUCOPYRANOSID

4-METHYLUMBELLIFERYL-B-D-GLUCOPYRANOSIDE

4-METHYLUMBELLIFERYL-B-D-GLUCOSIDE

4'-METHYLUMBELLIFERYL-BETA-D-GLUCOPYRANOSIDE

4-METHYLUMBELLIFERYL-BETA-D-GLUCOPYRANOSIDE

3-Methylumbelliferyl

7-(beta-D-glucopyranosyloxy)-4-methyl-2H-1-benzopyran-2-one

4-METHYLUMBELLIFERYL-SS-D-GLUCOPYRANOSIDE

2H-1-Benzopyran-2-one, 7-(β-D-glucopyranosyloxy)-4-methyl-

4-Methylumbelliferyl β-D-glucopyranoside

4-Methylumbelliferyl-beta-D-glucopyranoside USP/EP/BP

4-Methylumbelliferyl β-D-Glucoside

7-(B2

-D-glucopyranosyloxy)-4-methyl-2H-1-benzopyran-2-one

4-Methylumbellifery-β-D-glucopyranoside

4-Methylumbelliferyl-β-D- Glucopyranoside extrapure

2H-1-Benzopyran-2-one,7-(b-D-glucopyranosyloxy)-4-methyl-

4-MU-GLU

4-MU-β-Gluc

fluorogenic,substrate,4 Methylumbelliferyl β D Glucopyranoside,Inhibitor,chromogenic,4MethylumbelliferylβDGlucopyranoside,inhibit,4-methylumbelliferyl,fluorescent

2H-1-Benzopyran-2-one, 7-(β-D-glucopyranosyloxy)-4-methyl-

4-Methylumbelliferone- β- D-glucoside